Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVVAQQLGQWAEQTALKLLKEQNYEWVASNYHSRRGEVDLIVKRGNELIFVEVKARGQGNYGQACEMVTLSKQKKIIKTAMRFLQRYPSYQD-FYCRFDVICFDFPQKIAKTVQQDFSKFHYDLQWIENAFTLD- 3FOV Chain:A ((25-132)) ---------SAEASAADYLERQGYRILARRFKTRCGEIDLVAQRDALVAFVEVKARAYA--------VTPRQQSRIVAAAEAWLSRHPEH-AMSELRFDAILIAPNTAP---------------RHLPGAFDATP

General information: TITO was launched using: RESULT: Template: 3FOV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 445 -44713 -100.48 -447.13 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -100.48 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.755

(partial model without unconserved sides chains): PDB file : Tito_3FOV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FOV-query.scw PDB file : Tito_Scwrl_3FOV.pdb: