Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIFNKMKKDKIFILLGLFGTSVYAAEPITSSTDAVIRQQQRDEALQKQIQPTATVQTGLEKQLQS-------KPQL---QFLKSHSEDICFEIKKFILIGDDARRFTFAMRPITQGEHNLVGRCIGVQGLNQALDLIQNSIISHGYVTTRMLLPQQNIASGEIKLQV----IAGKVDQIKFVEGTSKRAHKFNALPVKSGDILNVRDIEQGLENFKRVPTVEADFKIKPSEQKTAPGYSDLELAWQQSKPYRIHLGIDDAG--SDSTGKYQGTATLSLDHLFTANDLFYGSYNHDLGGGDSGKRGTDGYYLSYSIPYHYWLLSTSYSQSNYNQTVAGASESYNYSGESKLIGADLSRVLYRDAKRKTTASVGGWYRESQNYINDVEVEVQRRKTAGWKASLDHSEYLSHATLNGNVTYKRGTGAFNAMYAPEEDFGEAYTRVGIWQANASLQVPFKVGQQNLQYLAEWRMQHSKKPLTPQDRFSIGNRYTVRGYDGEQTLLADNGFLVRNELSGSIPKLPMQWYSGIDYGEVGGTTAHKPNPLVGTSLLGAVIGLRGQVFKSVSYDAFVGAPLKKPEYFKTDDFTTGFSVNWMY 4QL0 Chain:A ((14-487)) -----------------------------------IDDRQRKEQLQRDIE-RALTRPPVELNPQSEAAAPARKPDATSGHTVTVHAVDLDF--------GVEGRLFDPA--PLVQ---DYLNRPLDNEQLFLLVKALSAALYDRGYATSIVTFVPPGVVDGVLKLKVEWGRIKGWLIDGKPLEGTRDRMMVFSAMPGWQDKVLNTFDIDQANYNINNGGKT-GNITIVPADEY---GYSYLDLQLQRRALPRVSLGMDNSGPGTPENGRYKYNASVTANDLLGLNDTL-GLYIGNRYYRDAGHDAERNYDLMYSVPLGRTRLDLQTGYSTYRNLLK--YGQYQSAGNSRSFGLKATRLLYRDTRSQFSVYGGLKLRQNKNYLAGTRLDVSSKHYSDVTVGMQYSTQRGANAYFGDLSFTRGV--------------------SRFNGSLAWTRYMALAGQPIQWASQLGFQYSRQQLLNSYQITVGDEYTVRGYNLRTSQSGDSGVYLSNTLT-----VPVQF-----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4QL0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1697 50673 29.86 118.95 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 29.86 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.212

(partial model without unconserved sides chains): PDB file : Tito_4QL0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QL0-query.scw PDB file : Tito_Scwrl_4QL0.pdb: