Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------------------------MKLEQKIIDLLCEIPDNVDYTDVAEDLDLEDISEIRIKQLRELLTNSDIYTISSC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 5TNV Chain:A ((21-326)) MYSAHTWPIAANMLGFGNRAPDGGHIKDAPAGVWAKQLRQVRELGFDHIDPTD--AWVPLAALSDSRIEEFRTVLADEGL-AISSISMTRSSIVDVENGEKNLADAHRLIDLAPSFGATIVNTGFMQALTPEQEKQIWFWLVQGHVDDPALRDLAIERVRELGDHARTNGIQLSLEMYEDTYIGTPDDAVAFIKDVDHDAVGLNPDLGNLVRLHRPMPHPSEMYAKVLPYSNFWHIKNYSRDFDPATGAYSSAPLPLKYGYVNYRQIIRLALELGYTGPFCCEHYGSDSLGVCAENREYILQVLTSALA

General information: TITO was launched using: RESULT: Template: 5TNV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 113 -1624 -14.37 -31.23 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : -14.37 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.782

(partial model without unconserved sides chains): PDB file : Tito_5TNV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5TNV-query.scw PDB file : Tito_Scwrl_5TNV.pdb: