Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR 4ADV Chain:O ((1-88)) -SLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTRLIERLGLRR

General information: TITO was launched using: RESULT: Template: 4ADV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain O - contact count / total energy / energy per contact / energy per residue : 233 -29651 -127.26 -336.94 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain O : 0.90 3D Compatibility (PKB) : -127.26 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.676

(partial model without unconserved sides chains): PDB file : Tito_4ADV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ADV-query.scw PDB file : Tito_Scwrl_4ADV.pdb: