Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKNILFDGLRSVARIGETAVVAAKAGIKYATDKPSNAKLMRETFESLGSTYIKLGQFIASTPSL-FPREYVEEFQGCLDQTPTLPFSYIQGVLASEFEGRDLSQIFSYIDETPLASASIAQVHAAKLTTGEDVVIKVQKPGVETILYTDLNVVHWAAKLLERAVPKIKFAALSDIVDEIKTRMVREVDFIEEAQNLDDFVEYLNISQNQAATAPKVYHQFSTRRVLTMQRLYGVPLTDFSVVKQYAKDPSQVLITAMNTWFGSLMLCKSFHADLHAGNLMLLE-DGRVGFIDFGIVGQLKPEVWTACIAFMDALQKTDYQAMAENMLKMGMTHNKIDVQVLAQD---LERLFNGVLMADPQQILASNPADLNDIMMDMVAVGERHGIKFPRDFAL-LFKQMLYFDRFMRILAPYTDIYADQRLKMVQNMEPASLLKH 4PED Chain:A ((4-387)) -----------------------------------ANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNND-LGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNML-P--EGLFPEHLIDVLRRELALECDYQREAACARKFRDLLK--GHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLS--QEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGY-EVKVMEDAHLDAILILGEAFAS--DEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYC--------

General information: TITO was launched using: RESULT: Template: 4PED.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2027 -41365 -20.41 -109.43 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -20.41 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.69 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_4PED.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4PED-query.scw PDB file : Tito_Scwrl_4PED.pdb: