Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPAYKAPLHDIRFLMNEVLDYPAHYKTLSNGESADPDTVDMILEGAADYCENVLSPLNQSGDEEGCHFDNGEVKTPKGFKEAYDQFVMGGWQGLSYPEEFGGQGLPMSLNLIKSEMMGTANWSFTMYPGLSSG-CMNTILQFGTDEQKQTYMPKLVEGTWSGTMCLTEPQCGTDLGQVKTKAEPQA-DGTYKISGTKIFISAGEHDLTENIIHIVLARLPDAP----AGTRGISLFIVPKFIPTAEGGVGERNTVSCGSIEHKMGIRASATAVLNFDN---ATGYLIGEVNKGLHAMFTFMNTARIGTAVQGIAHAELSFQGALPYAKERMSMRALSGKKDPDKVADAIIHHADVRRMLLTQKAIAEGGRSMIYYAAQLADKMTDALTRGDQAAFEDYDDKLGFYTPILKGFLTELGLEAANHGMQVYGGHGYIKEWGMEQIVRDARISTLYEGTTGVQALDLIGRKVLLSSKGK--------------VVREYTAEILKFCA---AHAR--NKYLRRFAWDLTKLCAQWNTLTVRIMLAARK-------DRDIVSSASVDFLMFSGYVMMAYFWAQQAVVASEKLEAGNGQETPEFYKAKIKVADFYFDRLLPRAQGHAESMVTTSRTLTSLPAEHFSFDY 2UXW Chain:A ((53-577)) -------------------------------------FLKELVEPVSRFFEEVNDPAKN--DALEMV--------E---ETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGL--AD--IFTVFAKTPVTDPATGAVKEKITAFVVERGFG----------GITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFG------------EKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGAT---------------DFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLF-VALQGCM-DKGKELSGLGSALKNPFG--------------SGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVV------VLS----RASRSLSEG-----HPTAQHEKMLCDTWCIEAAARIREGMAALQSDP---------------

General information: TITO was launched using: RESULT: Template: 2UXW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2416 -42205 -17.47 -89.80 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -17.47 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_2UXW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UXW-query.scw PDB file : Tito_Scwrl_2UXW.pdb: