Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQSERWWQDSSVTAELFQRPKSFEFIQATRLLRHMPANDAALSWCDHFKFETSFNLNFPATEIESLELVDERVHLTNLIVGLTGIQGTLPYTYTNKIKQAPRQQRAETKEFLSLFNHKLTSQYVESSITYHLPVRYEIENKNDYLDILHALNGYVRSQHQQQDLDEYFAEFSGLMQGQNNTVHALKTMLSCIFKHEITIKEFVQESFKLAGDQLTTLGGSQPSLLGINTFCGETIQQIDGKIEIQIGPLKHQQYLRFLPHQELSLKLKKIVETWCSPTLSIDLRLILDESEIQPVRLTQGQEGGLGQGAFLMSRKPNTHNDETCYSLIGEQI 2LC0 Chain:A ((56-93)) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLAPNEYIITLGVHDFEKLGADPE--LKSTGFARDLADYI---------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2LC0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 43 -7415 -172.43 -195.12 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : -172.43 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.758

(partial model without unconserved sides chains): PDB file : Tito_2LC0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LC0-query.scw PDB file : Tito_Scwrl_2LC0.pdb: