Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATKKAGGSTKNGRDSNPKMLGVKVYGGQTVTAGNIIVRQRGTEFHAGANVGMGRDHTLFATADGVVKFEVKGQFGRRYVKVETV 5DM6 Chain:T ((2-84)) -AHKKGVGSSKNGRDSNPKYLGVKKFGGEVVKAGNILVRQRGTKFKAGQGVGMGRDHTLFALSDGKVVFINKGKG-ARFISIEAA

General information: TITO was launched using: RESULT: Template: 5DM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain T - contact count / total energy / energy per contact / energy per residue : 282 -31592 -112.03 -380.62 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain T : 0.86 3D Compatibility (PKB) : -112.03 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_5DM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DM6-query.scw PDB file : Tito_Scwrl_5DM6.pdb: