Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNVRHSFPKNIFRAYDIRGKLS-YLTTDVVRSIAYGLAQQYKQAEQTQLIIGYDARLTSPAYAHLIEEILVEQGLNVTNIGCCSTPMMYYIAREFG-GNGIMVTASHNPKSDNGIKWILRGEPPSPEMIQQVGEFAQT--YVPTHTISLLELSTPQFNSKFCKKYQQAIFNDIQLKRPLKVVLDGLHGSAGHCSKLVLEKMGCEVIALRTTPNGEFPDHAPDPSHAAHLKELRKTIIEQGADIGIALDGDGDRVVLLDEKANILTADRLLSLFAQMCLEQQPDKEIVFDVKCSLMVQRTVERLGGKPKMIRTGSSFLRAYLSQSNGNAIFGGEYAGHYVFNDGRGFGYDDGLYAALRVMEYFTKSSATTISDLFSNYPERCCTEDTYIGTHQSDP-K-HVLQDIEILSHRLGARISKIDGVRLDFDDGFGIIRASNTGEYFTVRFDADNPLRLKEIQQKFIDMLQERYPQIAQELSEA 4MRQ Chain:A ((1-452)) ------LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLA-------SGVGSVE-QVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKE-T-GALLAGEMSGHVFFKE-RWFGFDDGIYSAARLLEILSQD-QRDSEHVFSAFPSDISTPEINI--TVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLP------

General information: TITO was launched using: RESULT: Template: 4MRQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2830 -2532 -0.89 -5.68 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -0.89 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.581

(partial model without unconserved sides chains): PDB file : Tito_4MRQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MRQ-query.scw PDB file : Tito_Scwrl_4MRQ.pdb: