Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDFLSEHLIYRDDDFMVIHKPSDILSVPGKGDLH-DSVLTRLVAIEPRTLLIHRLDRDTSGILVFGLSKRGQSAIARQFQDRQTSKIYEALVAGHLE-GEGTVDIPVVYDPSRPPLHIVDASHNKPALTHWQAIEHFQIQGQPVTRVKLTPITGRSHQLRVHMQYLGHPIVGDTLYATPE-QLLVPRLCLHAKQLSFNHPVTGESLTFNCPVPF 2I82 Chain:A ((14-217)) --------ILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEY---AADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF

General information: TITO was launched using: RESULT: Template: 2I82.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1051 -43451 -41.34 -216.17 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -41.34 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_2I82.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I82-query.scw PDB file : Tito_Scwrl_2I82.pdb: