Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHMVTTKKAKVQFNWQDPFLIEQQLSPDERMIHDAAHAYCQERLQPRVLEQFRHETTDPSIFREMGELGLLGPTIPEQYGGAGLNYVSYGLVAREIEYVDSGYRSMASVQSSLVMVPIHEFGTEEQKQKYLPKLATGEYIGCFGLTEPDHGSDPGSMITRAKKVEGGYRLTGAKMWITNSPIADVFVVWAKEVSAEGNVGDICGFILEKGWEGLSAPAIHGKVGLRASITGEIVMDNVFVPEENAFPEIRGLKGPFTCLNSARYGIAWGAMGAAEFCWHTAHQYTMDRKQFGRPLAANQLIQKKLADMQTEIALGLQAALRFGRMKDEGIASVEGTSLIKRNNCGKALDIARMARDMMGGNGISDEFGVARHLVNLEVVNTYEGTHDVHALILGRAQTGIAAFSN 3EOM Chain:A ((4-394)) -----------ATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEP----DPGSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAK--LDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNG-SDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAF--

General information: TITO was launched using: RESULT: Template: 3EOM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2157 -167429 -77.62 -433.75 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.94 3D Compatibility (PKB) : -77.62 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.94 QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_3EOM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EOM-query.scw PDB file : Tito_Scwrl_3EOM.pdb: