Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMFTKLALVSSLAISANAMAMQSMDDAALSAATGQDGINIGIALGTSGISIDKLYLHDNDGLATTTGITGATGTAGALAISDVTLKQTGTGNLLDLAIDTNGASST---NGAFLNVAATVGAVDIHVGSIGVGTSGTVNETTALRGITETAPTEIISGLDLS--LGQITANVQLGSTPQGAMIK--VDSALKGGLTISNLGINDAAGGGSILLDKVMVRGAGNATGDLDVKADISVTGNGLQVKSTSAQDMNVYVGGVHLGTNTKASDGTWGTGAVKAASIGDLEIQGLNVANTTITISGH 1Q5P Chain:A ((20-210)) ----------------------------------------------------------------------GLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALDNSIGVLGVAPSAELYAVKVLGASGSGAISSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNEGAGSIDYPARYANAMAVG-ATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLN--------------------------------------

General information: TITO was launched using: RESULT: Template: 1Q5P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1093 -14072 -12.87 -76.48 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -12.87 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.302

(partial model without unconserved sides chains): PDB file : Tito_1Q5P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q5P-query.scw PDB file : Tito_Scwrl_1Q5P.pdb: