Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEKKMKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGVAAGVVQSFQNC-LRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFLAKRQTRLNDIDLGNKKKIEIVNAFLP--------------------VKHLNVDRVSETISSLERERAEVLVSSMAFGVDNGEPERVVYEAASVKS-------IPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTEDSVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRA---SNGVYFEVGGTTTNIGVI-------KNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGI-IDVGPRSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANVLGLVQEEHFSYGNVP----SARKAIQA-LADYCHTTVEDIAEQIMEKSYAKIEPVILELADKYHLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVA----LAMVRDVVERIIPSPS-----------KEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQ---TSKVTAIATGSTEVKATDLTKEITTEEALELAAE--DMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIID-QKGFIKVQRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQLQLLM-DLEVSTMEPEEEVIVVAGNIKQT 5L9W Chain:B ((8-718)) ------DAINSIDIDVGGTFTDFVLTLDGERHIAKCPT--TPHDLSIGFLNAVEAGGDKVGLSVEELLPR-IDIIRYSTTVALNRLLQRQGPRIGLLTTEGHEDAILIGRGAQWTDGQRVAERRNIAVQNKPLPLIERDLILGVRERIDSSGSVVRPLDEEDVRTKLRMLMDRGARAIVVSLLWSFMNPAHEKRVREIIREEYKEYHIGFVPVVMSHSVVSKIGEYERTMTAVLDAYLQRSMQNDIGATWDKLRAKGYHGAFLMIHNSGGSADIFKTPASR--TFNGGPVAGLMGSAYFANKLGYKNVVAGDVGGTSFDVALVVESSVRNYTFRPVIDKWMVN-----VTMMQTISVGSGGGSIAKVDRSGTRLEVGPRSAG-------------SMPGP------------------VCYDLGGTEPTVTDADVVLGYINPDTYYGGRMPLNKAKAEKAIREKIAQPLGIETIEAAALIRYIVDENMASAIKREVHMRGYHPEDFVLFAFGGAGPTHMAGLKGDIPKAVVFPA-APVFCAMGSSIMDIVHMYEQSRRMVFMEPGTEKFVVDYEHFNQTVDTMIERARQELRSEGLEVDDASFGLELDMLYGGQVNLKRMSSPLLHIRTAEDALKVYQAFETEFSEAFSPLVVNKPGGVFLDNFVLRVTVPTWKPPIPEYPLQGTDPSAAFLGKRKAYWPETK------------HWADTPTYQFELLQ-------AGNVIDGPAIVEAELTTIVVPPRQRLSIDTHGLAILEAIDPA--

General information: TITO was launched using: RESULT: Template: 5L9W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 3559 35821 10.06 55.54 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : 10.06 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.380

(partial model without unconserved sides chains): PDB file : Tito_5L9W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5L9W-query.scw PDB file : Tito_Scwrl_5L9W.pdb: