Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKMTRRSTMLETYLEKSIFRQVYICEQLHEK-GTIQIREIADQLNVCPLTVTNDLECITDILHQQIISVEKSRSSFTVAFDSSFSRLALTQLIYQRSDFFNVLGHYLSGEH-NWSNIADTTFISLSKVYNLRNELINFFK-QMQYLNAD--GHFEIPEKDYRSLLLT-IIYETNRTELIQLNKSIIQSGQQLIDYVEKHFFSRSYPTVEKQFILLGIAIGLQRSKTNPIYFSQEEKRVA-R---HTPLFQLIQKGLEQLSFSLCHDEDECLYIYFLFNSRNYLCDNFELLQKDLNVVYQNHVADNPLVIELSQKLILSLNISEENQILFDKALLPFIRSLWADIQIFQ--------PDKTYLLNEEQRALYLEVHEILEQWRKQNNLFLR--WNENSIRKLTISLSLLN-E-HKRKSPIEVFIVAPSDFRY-LYYRQQLEDILGEHFSISNIICKQLREIVDDTFFCTQRIILCDSSLYQEGLGSEKTIIYPITFQTIHTVIDQLNKQI 5WAY Chain:B ((1-487)) ----------MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDL--IFH------RIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSS-EPLSQLLELVYKET-SFPMNLSTHRMLKLLLVTNLYRIKFGHFMEV-------LDFLMQAEGIEGVAQSFESE-YNISLDEEVVCQLFVSYFQKMFFIDESLFMKCV--KKDSYVEKSYHLLSDFIDQISVKYQIEIENKDNLIWHLHN--TAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELS--KESLEDSPYDIIISNFIIPPIE----NKRLIYSNNINTVSLIYLLNAMM

General information: TITO was launched using: RESULT: Template: 5WAY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1810 -29713 -16.42 -66.17 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : -16.42 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.369

(partial model without unconserved sides chains): PDB file : Tito_5WAY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WAY-query.scw PDB file : Tito_Scwrl_5WAY.pdb: