Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTEHFDLANPVTK--VDDIPDYEMYSQTIDSLNKRF-GNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD----EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLYD-NLALYEYVIDLCLSRGGTLF 2YXO Chain:B ((34-220)) VFTDHSPMPPWYDPESRMRLEALPFYLLALERVRERAQDLYVGIGLEADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDHQEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKKFGHRLP--EEALLELAEPALRAVAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLV

General information: TITO was launched using: RESULT: Template: 2YXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 841 -18993 -22.58 -106.11 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -22.58 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.445

(partial model without unconserved sides chains): PDB file : Tito_2YXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YXO-query.scw PDB file : Tito_Scwrl_2YXO.pdb: