Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNFNNCVVLIIITELTLF----TNIYYIHEAQSSLIEDWAIFMAKEGKEMFQNKG 1TDU Chain:A ((51-85)) ------CHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWA---------------

General information: TITO was launched using: RESULT: Template: 1TDU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 65 -7234 -111.28 -233.34 target 2D structure prediction score : 0.00 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -111.28 2D Compatibility (Sec. Struct. Predict.) : 0.00 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.180

(partial model without unconserved sides chains): PDB file : Tito_1TDU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TDU-query.scw PDB file : Tito_Scwrl_1TDU.pdb: