Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISKRKHVIIFPILCKKIQGGGSTMIEEYIEKNILRQLFLCGQFYV-NKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDR--YSPRFTEMERRLLLLN-VSYRLGGFNSWELPESFFERADRFIESVTE-NSGRFYDKENKEILSIGFAISFLRQQVCAVTIDSKF-IEEIKKRPIYNYVES---AWENTDFQTYYKKEEFAFILTLFNLCNYGF-HSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMP----EKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILR-LTKEHLTIYIVTNSDVHYL-IYREALEA-VTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK 4R6I Chain:B ((3-473)) ----------------------AMLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFKK-NSMQSLAQKLHLQVGALYPIINQINYDIQSSHLNIKKKPLEISGREQDVRVFMLRLYCNI-PNDYWPFPYINK-QNITDLINKMEKILNVQ-MYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYKTVASITSELQNS-FGVTLHETEISFLALALLLSLGNSIT---NKT--LTS---YKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIKKALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYS--HFDCYEISLLTMHFETQRMLFKNNPKKIYVYTSQGCIHREYISALLEKRYNG-LIKIVRNTI----------DMEIDIIISN------------------EFPTERDFHE-----

General information: TITO was launched using: RESULT: Template: 4R6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1811 -5023 -2.77 -11.74 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : -2.77 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.492

(partial model without unconserved sides chains): PDB file : Tito_4R6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R6I-query.scw PDB file : Tito_Scwrl_4R6I.pdb: