Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISMKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGYLDSAN----AEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYIKP 2PD2 Chain:A ((1-108)) ---MKVVVQIKDFDKVPQALRSVINLYNDIKDAEIEVVLHQSAIKALLKDSDTRSIIEDLIKKNILIVGCENSIRSQNLSHDQLIPGIKIVTSGVGEIVRKQSEGWIYLAL

General information: TITO was launched using: RESULT: Template: 2PD2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 490 -33560 -68.49 -322.69 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -68.49 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.575

(partial model without unconserved sides chains): PDB file : Tito_2PD2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PD2-query.scw PDB file : Tito_Scwrl_2PD2.pdb: