Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIGDKKLNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQILQEQYNLNRTCDDVTITHDNG-------DNTYRAKATLD-NGSAININVEYYPKKDRVYVEIPYTEVLMLN 2I52 Chain:A ((1-121)) -SLYDPAEKYFNCTDIQRAF-FEAGIKLGAIFHQYTGI-PVNSENASMAEEFIERSTMIQPFVENVRISINNVYSYSSLNEKMLHAEVLINYNGKKVLGVLNYDEGLD--YPVMYAKEVL---

General information: TITO was launched using: RESULT: Template: 2I52.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 411 -19924 -48.48 -186.20 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -48.48 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.501

(partial model without unconserved sides chains): PDB file : Tito_2I52.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I52-query.scw PDB file : Tito_Scwrl_2I52.pdb: