Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEGVRDECRRLSGKEAY-AFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTFDLGKACDMFEVNILGMMVLTQKFAIDMAERR--QGHIINIASMAGK--MATAKSTVYSATKFAVLGFSNALRLELK--PLGVAVTTVNPGPIETDF---FDKADPSGSYLEKVGQIVLEPAKLAKMIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK 1XG5 Chain:C ((30-264)) --WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTP-----------------------------------

General information: TITO was launched using: RESULT: Template: 1XG5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1182 -60843 -51.47 -270.41 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.74 3D Compatibility (PKB) : -51.47 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_1XG5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XG5-query.scw PDB file : Tito_Scwrl_1XG5.pdb: