Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQTNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIERVKETYGRH 3V6I Chain:B ((5-104)) ----LGLIKSLAEKEKQLLERLEAAKKEAEERVKRAEAEAKALLEEAEAKAKALEAQYRERERAETEALLARYRERAEAEAKAVREKAMARLDEAVALVLKEVL------

General information: TITO was launched using: RESULT: Template: 3V6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 8 -738 -92.25 -7.38 target 2D structure prediction score : 0.87 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -92.25 2D Compatibility (Sec. Struct. Predict.) : 0.87 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.746

(partial model without unconserved sides chains): PDB file : Tito_3V6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V6I-query.scw PDB file : Tito_Scwrl_3V6I.pdb: