Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQDAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADFTEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMALSVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQSAPITKRNLNRKVTFSLI-SYSLLLFSGFLLLMVLLVIHT-SW-DITVWYHILNTFLFLLPIISFSACITSLVKNSETSGGIKDIFITGSCFI-GGVFVPAEYLPEMVSKIAAFTPTYWFVQNNNLISETL-SYNQ------------------TFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN 5DO7 Chain:C ((438-649)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVAT--MIFSSVC-YWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLRNIQEMPIPFKIISYFTFQKYCSEILVVNEFYGLNFTCGSMCAFTQGIQFIEKTCPGATSRFTMNFLILYSFIPALVILGIVVFKIRDHLI-------

General information: TITO was launched using: RESULT: Template: 5DO7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 621 -88419 -142.38 -491.21 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain C : 0.55 3D Compatibility (PKB) : -142.38 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.283

(partial model without unconserved sides chains): PDB file : Tito_5DO7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DO7-query.scw PDB file : Tito_Scwrl_5DO7.pdb: