Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSIIAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSFLLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQPLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN 5C90 Chain:L ((3-190)) --LIPTV---------AYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLAINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVM-------

General information: TITO was launched using: RESULT: Template: 5C90.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain L - contact count / total energy / energy per contact / energy per residue : 843 -124505 -147.69 -695.56 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain L : 0.95 3D Compatibility (PKB) : -147.69 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.95 QMean score : 0.581

(partial model without unconserved sides chains): PDB file : Tito_5C90.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C90-query.scw PDB file : Tito_Scwrl_5C90.pdb: