Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTRRLGQTLFSQPFLGEISMNLTIQEIAQAVG-SEC---SALTKITNVEFDSRKITEGSLFVPLAGTRDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEVVAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMGMDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVPADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVE--GETFTIPLPGSYNVTNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTFKNLP--TKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEELNQKYPQLPVFYL------EKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK 3ZM6 Chain:A ((1-454)) --------------------MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGARDGHDFIETAFENGAAVTLSEKEV----SNHPYILVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMAS-GSLLLAPADPIVEDYLPI-DKKVVRFGQG-AELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQD-QFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLEN--

General information: TITO was launched using: RESULT: Template: 3ZM6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2478 52997 21.39 120.45 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : 21.39 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.535

(partial model without unconserved sides chains): PDB file : Tito_3ZM6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZM6-query.scw PDB file : Tito_Scwrl_3ZM6.pdb: