Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLATLYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTRE-DEVIEITTNKGIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDSAIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELTDIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGVYAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS 3LZX Chain:A ((6-329)) -KVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEETHYSKTVIITAGNGAFKPRKLELENAEQYEGKNLHYFVDDLQKFAGRRVAILGGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHSVENLHASKVNVLTPFVPAELIGED-KIEQLVLEEVKGDRKEILEIDDLIVNYGFVSSLGPIKNWGLDIEKNSIVVKSTMETNIEGFFAAGDICTYEGKVNLIASGFGEAPTAVNNAKAYMDPKARVQPLHSTSLF-------

General information: TITO was launched using: RESULT: Template: 3LZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1822 -58462 -32.09 -181.00 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.90 3D Compatibility (PKB) : -32.09 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.574

(partial model without unconserved sides chains): PDB file : Tito_3LZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LZX-query.scw PDB file : Tito_Scwrl_3LZX.pdb: