Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYLTLPGD--DYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPGTT-PSYYFVIDPDGYKIEVIRG 4MTS Chain:B ((1-125)) MRILHSMLRVADLEAALEFYTRALDMRLLRRRDYPEGRFTLAFVGYQDERAAAALELTHNWDRDGYTQGDGYGHLAIEVEDAAVTCARARALGYRVTREAGLMQHGRSVIAFLEDPDGYKVELIQ-

General information: TITO was launched using: RESULT: Template: 4MTS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 474 -17595 -37.12 -144.22 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -37.12 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.693

(partial model without unconserved sides chains): PDB file : Tito_4MTS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MTS-query.scw PDB file : Tito_Scwrl_4MTS.pdb: