Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------------MTQEI-----------KKLPVIFLGLFFITVGLNWFLLPHD-----IASAGVGAIGHLVETAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHFFSLISGSLLFSLGVYTLYTVGASNGGITIP-----PIIFHKFFRLPMP-------QGLLLTNSLIVFLNYYVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE--------------------------------------------------- 5IPX Chain:A ((32-322)) HLFNHLFRYHYPSWDQILQELDTLSVATLNPDCHVPALNVEKTLYLAKTIQILVQHRQSEPYLVPAARANLAYSLQQLYKLGNDKIRGVINGMLPLVDAGCIGFERELIKGLPRVLTLQYPHTAPCTEWCLSHF---VGASGRLRSEVRDILT---THNGTCAPSFEWMASVVKKFFLVETVIYEDFQDTDFNVQLNLCFFWTAVVQMYQRCIY---EQKLVHIISTSLTLLKSTARSFFAWYDLYRPNLGSAALVKYTEHLIRALTPDCSDVELGELCSHLHHCKHALFS

General information: TITO was launched using: RESULT: Template: 5IPX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 499 -45824 -91.83 -245.05 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -91.83 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.284

(partial model without unconserved sides chains): PDB file : Tito_5IPX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5IPX-query.scw PDB file : Tito_Scwrl_5IPX.pdb: