Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYYFPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP 1X7V Chain:A ((7-74)) --LTLIATITAAPGHAEALEREL--RALVAPSRAEAGCLQYDLHQDRHDSHLFYMIEQWRDDAALERHQNTE-------------------------

General information: TITO was launched using: RESULT: Template: 1X7V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 217 -20755 -95.65 -305.22 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -95.65 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.762

(partial model without unconserved sides chains): PDB file : Tito_1X7V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X7V-query.scw PDB file : Tito_Scwrl_1X7V.pdb: