@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00072_AHK3_A: (2014-08-20 )
MSLFHVLGFGVKIGHLFWMLCCWFVSWFVDNGIEDKSGLLVGSVGDLEKTKMTTLKKKNKMWFWNKISSSGLKIPSFSYQFLGSVKFNKAWWRKLVVVWVVFWVLVSIWTFWYFSSQAMEKRKETLASMCDERARMLQDQFNVSMNHVQAMSILISTFHHGKIPSAIDQRTFSEYTDRTSFERPLTSGVAYAMRVLHSEREEFERQQGWTIRKMYSLEQNPVHKDDYDLEALEPSPVQEEYAPVIFAQDTVSHVVSLDMLSGKEDRENVLRARSSGKGVLTAPFPLIKTNRLGVILTFAVYKRDLPSNATPKERIEATNGYLGGVFDIESLVENLLQQLASKQTILVNVYDITNHSQPISMYGTNVSADGLERVSPLIFGDPLRKHEMRCRFKQKPPWPVLSMVTSFGILVIALLVAHIIHATVSRIHKVEEDCDKMKQLKKKAEAADVAKSQFLATVSHEIRTPMNGVLGMLHMLMDTELDVTQQDYVRTAQASGKALVSLINEVLDQAKIESGKLELEEVRFDLRGILDDVLSLFSSKSQQKGVELAVYISDRVPDMLIGDPGRFRQILTNLMGNSIKFTEKGHIFVTVHLVDELFESIDGETASSPESTLSGLPVADRQRSWENFKAFSSNGHRSFEPSPPDINLIVSVEDTGVGIPVEAQSRIFTPFMQVGPSISRTHGGTGIGLSISKCLVGLMKGEIGFSSTPKVGSTFTFTAVFSNGMQPAERKNDNNQPIFSEFRGMKAVVVDHRPARAKVSWYHFQRLGIRVEVVPRVEQALHYLKIGTTTVNMILIEQEIWNREADDFIKKLQKDPLFLSPKLILLANSVESSISEALCTGIDPPIVIVKPLRASMLAATLQRGLGIGIREPPQHKGPPALILRNLLLGRKILIVDDNNVNLRVAAGALKKYGADVVCAESGIKAISLLKPPHEFDACFMDIQMPEMDGFEATRRIRDMEEEMNKRIKNGEALIVENGNKTSWHLPVLAMTADVIQATHEECLKCGMDGYVSKPFEAEQLYREVSRFFNSPSDTES
Atome Classification :
(7 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360..-.....-370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
S
L
F
H
V
L
GF
G
V
K
I
G
H
L
F
W
M
L
C
C
W
F
V
S
W
F
V
DNGIEDKS
G
L
L
V
GSVGD
L
E
K
T
K
M
T
T
L
KKKN
K
M
W
F
W
N
KISSSGLKIPS
F
S
Y
Q
F
L
GSVKF
N
K
A
W
W
R
K
L
V
V
V
W
V
V
F
W
V
L
V
S
I
W
T
F
W
Y
F
S
S
Q
A
M
E
K
R
K
E
T
L
A
S
M
C
D
E
R
A
R
M
L
Q
D
Q
FN
V
S
M
N
H
V
Q
A
M
S
I
L
I
S
T
FHHGKI
P
S
A
I
D
Q
R
T
F
S
E
YTDRTSFERPLTS
G
V
A
Y
A
M
R
V
L
H
S
E
R
E
E
F
E
R
QQG
W
T
I
R
K
M
YSLEQNPVHKDDYDLEALEPSPVQEEYA
P
V
I
F
A
Q
D
T
V
S
H
V
V
S
L
DMLSG
K
E
D
R
E
N
V
L
R
ARSSGK
G
V
L
TAPFP
L
I
KTNR
L
G
V
I
L
T
F
A
V
Y
K
RDLPSNA
T
P
K
E
R
I
EATNGYLG
G
V
F
D
I
E
S
L
V
E
N
L
L
Q
Q
L
ASK
Q
T
I
L
V
N
V
Y
DITNHSQ
P
I
S
M
YGT-NVSAD-
G
L
E
R
V
S
P
L
IFGDP
L
R
K
H
E
M
R
CRFKQKPP
W
P
V
L
S
M
V
T
S
F
G
I
L
V
I
A
L
L
V
A
H
I
I
H
A
T
V
S
R
I
H
K
V
E
E
D
C
D
K
M
K
Q
L
K
K
K
A
E
A
A
D
V
A
K
S
Q
F
L
A
T
V
S
H
E
IRT
P
M
N
G
V
L
G
M
L
H
M
L
MDTELDV
T
Q
Q
D
Y
V
R
T
AQAS
G
K
A
L
V
S
L
I
N
E
V
L
D
Q
A
KIESG
K
L
E
L
E
E
V
R
F
D
L
R
G
I
L
D
D
V
L
S
L
F
SS
K
S
QQKG
V
E
L
A
V
Y
ISDRVPDMLIGD
P
G
R
F
R
Q
I
L
T
N
LMGN
S
I
K
FTEKG
H
I
F
V
T
V
H
L
V
D
E
L
F
E
SIDGETASSP
E
S
TLSGLPV
A
D
R
QRSWEN
F
K
A
FSSNGHRSFEPSPP
D
I
N
L
I
V
S
V
EDTGVGIPVEAQS
R
I
F
T
P
F
M
Q
VGPSISRTHGGTGI
G
L
S
I
S
K
C
L
V
G
L
M
KGEIGFSSTPKVGS
T
F
T
F
T
A
V
FSNGMQPAERKNDNNQ
P
I
F
S
E
FRG
M
K
A
V
V
VDHRPAR
A
K
V
S
W
Y
H
F
Q
RL
G
I
R
V
E
V
V
P
R
V
E
Q
A
L
H
Y
L
K
IG
T
T
T
V
N
M
I
L
I
E
Q
E
I
WNR
E
A
D
D
F
I
K
K
L
QKDPLFLS
P
K
L
I
L
L
A
N
S
V
E
S
S
I
S
E
A
L
CTGIDP
P
I
V
I
V
K
P
L
R
A
S
M
L
A
A
T
L
Q
RGLGIGIREPPQHKG
P
P
A
L
I
L
R
N
L
LLG
R
K
I
L
I
V
DDNN
V
N
L
R
V
A
A
G
A
L
K
KYGA
D
V
V
C
AESG
I
K
A
I
SLLKPPHEF
D
A
C
F
M
DIQMPEMD
G
F
E
A
T
R
R
I
R
D
M
E
E
E
M
N
K
RIKNG
E
A
L
I
V
ENGNK
T
S
W
H
L
P
V
L
A
M
T
A
D
V
I
Q
A
T
H
E
E
C
L
K
CGMDGYVSKPF
E
A
E
Q
L
Y
R
E
V
S
R
FFNSPSDTES
6
PsiBlast_PDB
91.04
61%
-69
- C1 -
3T4S
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
Q
D
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
89.71
61%
-68
- C1 -
3T4T
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
Q
D
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
89.57
61%
-71
- C1 -
3T4O
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
Q
D
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
89.42
61%
-69
- C1 -
3T4L
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
--
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.29
61%
-69
- C1 -
3T4J
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
--
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
88.86
61%
-69
- C1 -
3T4Q
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
I
D
Q
E
T
F
A
E
Y
T
A
R
T
A
F
E
R
P
L
L
S
G
V
A
Y
A
E
K
V
V
N
F
E
R
E
M
F
E
R
Q
H
N
W
V
I
K
T
M
---------------
D
R
G
E
P
S
P
V
R
D
E
Y
A
P
V
I
F
S
Q
D
S
V
S
Y
L
E
S
L
D
M
M
S
G
E
E
D
R
E
N
I
L
R
A
R
E
T
G
K
A
V
L
T
S
P
F
R
L
L
E
T
H
H
L
G
V
V
L
T
F
P
V
Y
K
S
S
L
P
E
N
P
T
V
E
E
R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
E
S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
--
E
E
A
D
R
S
L
S
H
E
S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.40
61%
-68
- C1 -
3T4K
1
AHK4_ARATH
A:
[8-268]
------------------------------------------------------------------------------------------------------------------------
R
R
E
E
V
L
V
S
M
C
D
Q
R
A
R
M
L
Q
D
Q
F
S
V
S
V
N
H
V
H
A
L
A
I
L
V
S
T
F
H
Y
H
K
N
P
S
A
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E
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A
R
T
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K
V
V
N
F
E
R
E
M
F
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Q
H
N
W
V
I
K
T
M
---------------
D
R
G
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P
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P
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Y
A
P
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Q
D
S
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N
P
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R
I
A
A
T
A
G
Y
L
G
G
A
F
D
V
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S
L
V
E
N
L
L
G
Q
L
A
G
N
Q
A
I
V
V
H
V
Y
D
I
T
N
A
S
D
P
L
V
M
Y
G
N
Q
D
E
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A
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R
S
L
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S
K
L
D
F
G
D
P
F
R
K
H
K
M
I
C
R
Y
H
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------