@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00102_PTN1_R: (2014-08-24 )
MEMEKEFEQIDKAGNWAAIYQDIRHEASDFPCRIAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQKEEKEMVFDDTNLKLTLISEDVKSYYTVRQLELENLATQEAREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHVPPPPRPPKRTLEPHNGKCKELFSNHQWVSEESCEDEDILAREESRAPSIAVHSMSSMSQDTEVRKRMVGGGLQSAQASVPTEEELSPTEEEQKAHRPVHWKPFLVNVCMATALATGAYLCYRVCFH
Atome Classification :
(32 SA)
.........10........20........30........40........50........60-.---.----.......70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200..--------.....210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
M
E
K
E
F
E
Q
I
DKAG
N
W
A
A
I
Y
Q
D
I
R
H
EASDFP
C
R
I
A
KLPKNKNRNRYRDVSPFDHS
R
I
K
L
H--Q---E----DNDYI
N
A
S
L
I
K
M
E
E
A
QR
S
Y
I
L
TQGPLP
N
T
C
G
H
F
W
E
M
V
W
E
QKSR
G
V
V
M
L
N
R
I
M
E
KGS
L
K
C
A
Q
YWPQKEEK
E
M
V
FDDTN
L
K
L
T
L
I
S
E
D
V
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
A
T
Q
E
A
R
E
I
L
H
FHYTTWPDFGVPE
S
P
A
S
F
L
N
F
L
F
K
V
RESGSL--------SPEHG
P
I
V
V
H
CSAGIGRSGT
F
C
L
A
D
T
C
L
L
L
MDKRKDPSSV
D
I
K
K
V
L
L
E
M
R
R
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
IEG
A
K
F
IMGD
S
S
V
Q
D
Q
W
K
E
L
S
H
EDLEPPPEHVPPPPRPPKRTLEPHNG
K
C
K
E
L
F
SNHQWVSEESCED
E
D
I
L
A
R
EESRA
P
S
I
A
V
H
S
M
S
SMS
Q
D
T
E
V
R
K
R
M
VGGGL
Q
S
AQASVP
T
E
EELSP
T
E
E
E
Q
KAHRPVH
W
K
P
F
L
V
N
V
C
M
A
T
A
L
A
T
G
A
Y
L
C
Y
R
V
CFH
53
PsiBlast_CBE
99.16
96%
-104
- C3 -
2ZMM
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
98.76
95%
-101
- C3 -
3I80
4
PTN1_HUMAN
A:
[2-299]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
98.71
96%
-101
- C3 -
2QBR
1
PTN1_HUMAN
A:
[2-299]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
98.66
96%
-104
- C3 -
2AZR
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
98.66
96%
-103
- C3 -
2ZN7
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
98.62
95%
-102
- C3 -
1EEN
3
PTN1_HUMAN
A:
[1-299]
M
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
98.46
96%
-101
- C3 -
2H4K
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
98.43
95%
-103
- C3 -
1PXH
3
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
98.41
96%
-104
- C3 -
2HB1
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
98.36
95%
-102
- C3 -
1SUG
5
PTN1_HUMAN
A:
[2-299]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
98.32
96%
-102
- C3 -
2QBP
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
98.30
95%
-101
- C3 -
1EEO
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
98.28
96%
-102
- C3 -
2QBQ
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
98.25
96%
-101
- C3 -
2H4G
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
98.14
96%
-101
- C3 -
2QBS
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
98.14
95%
-100
- C3 -
1AAX
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
98.10
95%
-101
- C3 -
1PTY
2
PTN1_HUMAN
A:
[2-299]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
98.06
96%
-104
- C3 -
2B07
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
97.85
95%
-105
- C3 -
3QKQ
4
PTN1_HUMAN
A:
[2-297]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
F
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
---------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
97.76
95%
-106
- C3 -
3I7Z
4
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
97.44
95%
-99
- C3 -
1PTV
2
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
T
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
D
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
97.40
95%
-99
- C3 -
1L8G
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
T
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
D
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
97.32
95%
-101
- C3 -
1PTU
2
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
T
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
97.31
95%
-101
- C3 -
1BZC
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
D
M
R
K
F
R
M
G
L
I
Q
T
A
E
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
97.29
95%
-105
- C3 -
4I8N
1
PTN1_HUMAN
A:
[36-333]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
L
-------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
97.14
95%
-99
- C3 -
1PTT
2
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
T
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
64
Fugue
96.63
95%
-108
- C3 -
1BZH
1
PTN1_HUMAN
A:
[2-298]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
QE---------
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
D
M
R
K
F
R
M
G
L
I
Q
T
A
E
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
S
S
V
Q
D
Q
W
K
E
L
S
H
E
D
--------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
94.26
95%
-112
- C3 -
3EB1
1
PTN1_HUMAN
A:
[2-284]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
D
----------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
93.61
95%
-108
- C3 -
3D9C
1
PTN1_HUMAN
A:
[2-283]
-
E
M
E
K
E
F
E
Q
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
E
K
G
S
L
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
C
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
I
M
G
-----------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
89.61
95%
-104
- C3 -
3ZMP
1
?
B:
[18-288]
---------
I
D
K
S
G
S
W
A
A
I
Y
Q
D
I
R
H
E
A
S
D
F
P
C
R
V
A
K
L
P
K
N
K
N
R
N
R
Y
R
D
V
S
P
F
D
H
S
R
I
K
L
H
--
Q
---
E
----
D
N
D
Y
I
N
A
S
L
I
K
M
E
E
A
Q
R
S
Y
I
L
T
Q
G
P
L
P
N
T
C
G
H
F
W
E
M
V
W
E
Q
K
S
R
G
V
V
M
L
N
R
V
M
-----
K
C
A
Q
Y
W
P
Q
K
E
E
K
E
M
I
F
E
D
T
N
L
K
L
T
L
I
S
E
D
I
K
S
Y
Y
T
V
R
Q
L
E
L
E
N
L
T
T
Q
E
T
R
E
I
L
H
F
H
Y
T
T
W
P
D
F
G
V
P
E
S
P
A
S
F
L
N
F
L
F
K
V
R
E
S
G
S
L
--------
S
P
E
H
G
P
V
V
V
H
S
S
A
G
I
G
R
S
G
T
F
C
L
A
D
T
C
L
L
L
M
D
K
R
K
D
P
S
S
V
D
I
K
K
V
L
L
E
M
R
K
F
R
M
G
L
I
Q
T
A
D
Q
L
R
F
S
Y
L
A
V
I
E
G
A
K
F
--------------------------------------------------------------------------------------------------------------------------------------------------------
79
HHSearch
72.11
40%
-86
- C3 -
4GE6
1
PTN9_HUMAN
A:
[27-305]
--------------
G
I
Y
E
E
Y
E
D
I
R
R
E
N
P
V
G
T
F
H
C
S
M
S
P
G
N
L
E
K
N
R
Y
G
D
V
P
C
L
D
Q
T
R
V
K
L
T
--
K
---
R
SGHT
Q
T
D
Y
I
N
A
S
F
M
D
G
Y
K
Q
K
N
A
Y
I
G
T
Q
G
P
L
E
N
T
Y
R
D
F
W
L
M
V
W
E
Q
K
V
L
V
I
V
M
T
T
R
F
E
E
G
G
R
R
K
C
G
Q
Y
W
P
L
E
K
D
S
R
I
R
F
G
--
F
L
T
V
T
N
L
G
V
E
N
M
N
H
Y
K
K
T
T
L
E
I
H
N
T
E
E
R
Q
K
R
Q
V
T
H
F
Q
F
L
S
W
P
D
Y
G
V
P
S
S
A
A
S
L
I
D
F
L
R
V
V
R
N
Q
Q
S
L
A
V
S
N
MGAR-
C
P
E
P
P
I
V
V
H
C
S
A
G
I
G
R
T
G
T
F
C
S
L
D
I
C
L
A
Q
L
E
E
L
G
---
T
L
N
V
F
Q
T
V
S
R
M
R
T
Q
R
A
F
S
I
Q
T
P
E
Q
Y
Y
F
C
Y
K
A
I
L
E
F
A
E
K
E
G
M
-----------------------------------------------------------------------------------------------------------------------------------------------------
77
HHSearch
64.18
38%
-85
- C3 -
2P6X
2
PTN22_HUMAN
A:
[42-291]
---------------------------
K
T
Y
P
T
T
V
A
E
K
P
K
N
I
K
K
N
R
Y
K
D
I
L
P
Y
D
Y
S
R
V
E
L
S
--
L
ITD
E
----
D
S
S
Y
I
N
A
N
F
I
K
G
V
Y
G
P
K
A
Y
I
A
T
Q
G
P
L
S
T
T
L
L
D
F
W
R
M
I
W
E
Y
S
V
L
I
I
V
M
A
C
M
E
Y
E
M
G
K
K
K
C
E
R
Y
W
A
E
P
G
E
M
Q
L
E
F
--
G
P
F
S
V
S
C
E
A
E
K
R
K
S
D
Y
I
I
R
T
L
K
V
K
F
--
N
S
E
T
R
T
I
Y
Q
F
H
Y
K
N
W
P
D
H
D
V
P
S
S
I
D
P
I
L
E
L
I
W
D
V
R
C
Y
Q
----------
E
D
D
S
V
P
I
C
I
H
C
S
A
G
C
G
R
T
G
V
I
C
A
I
D
Y
T
W
M
L
L
K
D
G
I
I
P
E
N
F
S
V
F
S
L
I
R
E
M
R
T
Q
R
P
S
L
V
Q
T
Q
E
Q
Y
E
L
V
Y
N
A
V
L
E
L
F
K
---------------------------------------------------------------------------------------------------------------------------------------------------------