@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00433_SGK2_H: (2014-09-07 )
MQGLLTSGRKPSGGGRCTGRGGWRGQWCLKPWMGGADPPTPTLSCLLLPVPPELPDHCYRMNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPDTVASSSGASSAFLGFSYAPEDDDILDC
Atome Classification :
(27 SA)
.........10........20........30........40........50........60........70........80........90........100..-.....110.-.---..---...120.......130.-.-.....140.......-150.......160.....-..170.......180.....-..190.......200.......210-.......220.......230........240.......250--.-......260.....-----..---270.......280.......290...---...---..300----........310....---.....320---.........330.......--340.-........350....---...360.......370.......380.......390.......400-.......410.......420.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQGLLTSGRKPSGGGRCTGRGGWRG
Q
W
C
LKPWMGGADPPTP
T
L
S
C
L
L
LPVPPEL
P
D
H
C
Y
RMNSSPAGTPSPQPSRANG
N
I
NLGPSANPNAQPT
D
F
D
F
L
K
V
IGKG-NY
G
K
V
L
L
A
K
-R---KS---DGA
F
Y
A
V
K
V
L
Q
K
K
S
I
L
K
-
K
-
K
E
Q
S
H
I
M
A
E
R
S
V
L
L
K
-NVRH
P
F
L
V
G
L
R
YSFQTP
E
-
K
L
Y
F
V
L
D
Y
VNGG
E
L
F
F
H
L
Q
R
-
E
R
R
F
L
E
P
R
A
R
F
Y
A
A
E
V
A
S
A
I
G
Y
L
H
S
-
L
N
I
I
Y
RDLKPE
N
I
L
L
DCQ-G
H
V
V
L
T
D
F
G
L
CKEGVEPEDTTS--T-FCG
T
P
E
Y
L
A
P
E
V
L
R-----KE---PYDR
A
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
HGL-PP
F
---
Y
S
Q
---
D
V
S
Q
-----
M
Y
E
N
I
L
HQP--LQIP---GGR
T
V
A
-----
A
C
D
L
L
Q
S
L
L
H
K
D
Q
R
Q
RLGS--K--A-
D
F
L
E
IKN
H
V
F
FSPI
N
---
W
D
D
L
Y
H
KRLTPPFNPNVTGPADLKHF
D
P
E
F
T
Q
E
A
V
S
KSIGCTPDTV-ASSSGAS
S
A
F
L
G
F
SYAPEDDDILDC
1
PsiBlast_PDB
81.89
72%
-132
- C1 -
2R5T
1
SGK1_HUMAN
A:
[25-320]
-------------------------------------------------------------------------------
I
N
L
G
P
S
S
N
P
H
A
K
P
S
D
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
-
H
---
K
A
---
E
E
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
---------------
V
L
L
K
-
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
-
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
-
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
-
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
T
S
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
-
P
P
F
---
Y
S
R
---
N
T
A
E
-----
M
Y
D
N
I
L
N
K
P
--
L
Q
L
K
---
P
N
I
T
N
S
-----
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
--
K
--
D
-
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------
32
HHSearch
81.40
50%
-119
- C1 -
4GV1
5
AKT1_HUMAN
A:
[5-337]
-----------------------------------------------------------------------------------------
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
Q
N
--
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
S-
E
-
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
I
T
P
-----
S
M
E
C
V
D
S
E
R
R
P
H
F
P
Q
F
D
Y
S
A
S
-------
7
PsiBlast_PDB
78.47
52%
-121
- C1 -
3E8D
2
AKT2_HUMAN
A:
[6-323]
---------------------------------------------------------------------------------------------
D
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
-
K
-
D
E
V
A
H
T
V
T
E
-
S
R
V
L
Q
-
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
R
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
S
P
E
-----
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
P-
S
-
D
A
K
E
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
Q
S
I
T
------------------------------------
12
PsiBlast_PDB
78.16
52%
-124
- C1 -
3QKM
1
AKT1_HUMAN
A:
[5-309]
----------------------------------------------------------------------------------------
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
-
Q
-
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
--
S
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
------------------------------------
9
PsiBlast_PDB
77.95
52%
-116
- C1 -
3OW4
2
AKT1_HUMAN
A:
[5-309]
----------------------------------------------------------------------------------------
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
-
Q
-
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
--
S
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
------------------------------------
3
PsiBlast_PDB
77.22
72%
-130
- C1 -
3HDN
1
SGK1_HUMAN
A:
[25-316]
-------------------------------------------------------------------------------
I
N
L
G
P
S
S
N
P
H
A
K
P
S
D
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
-
H
---
K
A
---
E
E
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
---------------
V
L
L
K
-
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
-
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
-
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
-
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
T
S
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
-
P
P
F
---
Y
S
R
---
N
T
A
E
-----
M
Y
D
N
I
L
N
K
P
--
L
Q
L
K
---
P
N
I
T
N
S
-----
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
--
K
--
D
-
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
---------------------------------------------------------
2
PsiBlast_PDB
77.01
72%
-127
- C1 -
3HDM
1
SGK1_HUMAN
A:
[25-320]
-------------------------------------------------------------------------------
I
N
L
G
P
S
S
N
P
H
A
K
P
S
D
F
H
F
L
K
V
I
G
K
G
-
S
F
G
K
V
L
L
A
R
-
H
---
K
A
---
E
E
V
F
Y
A
V
K
V
L
Q
K
K
A
I
L
---------------
V
L
L
K
-
N
V
K
H
P
F
L
V
G
L
H
F
S
F
Q
T
A
D
-
K
L
Y
F
V
L
D
Y
I
N
G
G
E
L
F
Y
H
L
Q
R
-
E
R
C
F
L
E
P
R
A
R
F
Y
A
A
E
I
A
S
A
L
G
Y
L
H
S
-
L
N
I
V
Y
R
D
L
K
P
E
N
I
L
L
D
S
Q
-
G
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
H
N
S
T
T
S
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
H
-----
K
Q
---
P
Y
D
R
T
V
D
W
W
C
L
G
A
V
L
Y
E
M
L
Y
G
L
-
P
P
F
---
Y
S
R
---
N
T
A
E
-----
M
Y
D
N
I
L
N
K
P
--
L
Q
L
K
---
P
N
I
T
N
S
-----
A
R
H
L
L
E
G
L
L
Q
K
D
R
T
K
R
L
G
A
--
K
--
D
-
D
F
M
E
I
K
S
H
V
F
F
S
L
I
N
---
W
D
D
L
I
N
K
K
I
T
P
P
F
N
P
N
V
S
G
-----------------------------------------------------
13
PsiBlast_PDB
76.06
52%
-122
- C1 -
4EKL
1
AKT1_HUMAN
A:
[5-309]
----------------------------------------------------------------------------------------
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
-
Q
-
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
--
S
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
------------------------------------
39
HHSearch
75.66
37%
-116
- C1 -
4AW2
3
MRCKA_RAT
A:
[71-407]
-----------------------------------------------------------------------------------------
L
H
R
E
D
F
E
I
L
K
V
I
G
R
G
-
A
F
G
E
V
A
V
V
K
-
L
---
K
N
---
A
D
K
V
F
A
M
K
I
L
N
K
W
E
M
L
K
-
R
-
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
--
G
D
S
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
-
N
L
Y
L
V
M
D
Y
Y
V
G
G
D
L
L
T
L
L
S
K
F
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
-
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
D
M
N
-
G
H
I
R
L
A
D
F
G
S
C
L
K
L
M
E
D
G
T
V
Q
S
--
S
V
A
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
GG
K
G
---
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
-
T
P
F
---
Y
A
E
---
S
L
V
E
-----
T
Y
G
K
I
M
N
H
K
ER
F
Q
F
P
TQV
T
D
V
S
E
N
-----
A
K
D
L
I
R
R
L
I
C
-
S
R
E
H
R
L
G
Q
-----
N
-
G
I
E
D
F
K
K
H
P
F
F
S
G
I
D
---
W
D
N
I
--
R
N
C
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
D
---------------------
S
G
H
H
L
P
F
V
G
F
T
Y
T
S
S
C
------
11
PsiBlast_PDB
74.58
52%
-116
- C1 -
3QKL
2
AKT1_HUMAN
A:
[5-309]
----------------------------------------------------------------------------------------
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
-
Q
-
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
--
S
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
------------------------------------
10
PsiBlast_PDB
74.20
52%
-121
- C1 -
3QKK
2
AKT1_HUMAN
A:
[5-309]
----------------------------------------------------------------------------------------
R
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
A
-
K
-
D
E
V
A
H
T
L
T
E
N
R
V
L
-
Q
-
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
--
S
E
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
D
E
E
F
T
A
Q
M
I
T
------------------------------------
6
PsiBlast_PDB
73.66
52%
-121
- C1 -
3E88
2
AKT2_HUMAN
A:
[6-304]
---------------------------------------------------------------------------------------------
D
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
-
K
-
D
E
V
A
H
T
V
T
E
-
S
R
V
L
Q
-
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
R
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
S
P
E
-----
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
P-
S
-
D
A
K
E
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
Q
S
I
T
------------------------------------
8
PsiBlast_PDB
73.45
52%
-120
- C1 -
3D0E
1
AKT2_HUMAN
A:
[6-304]
---------------------------------------------------------------------------------------------
D
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
-
K
-
D
E
V
A
H
T
V
T
E
-
S
R
V
L
Q
-
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
R
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
S
P
E
-----
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
P-
S
-
D
A
K
E
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
Q
S
I
T
------------------------------------
5
PsiBlast_PDB
73.42
52%
-124
- C1 -
3E87
2
AKT2_HUMAN
A:
[6-304]
---------------------------------------------------------------------------------------------
D
F
D
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
R
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
R
K
E
V
I
I
A
-
K
-
D
E
V
A
H
T
V
T
E
-
S
R
V
L
Q
-
N
T
R
H
P
F
L
T
A
L
K
Y
A
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
T
E
E
R
A
R
F
Y
G
A
E
I
V
S
A
L
E
Y
L
H
S
-
R
D
V
V
Y
R
D
I
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
S
D
G
A
T
M
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
R
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
S
P
E
-----
A
K
S
L
L
A
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
P-
S
-
D
A
K
E
V
M
E
H
R
F
F
L
S
I
N
---
W
Q
D
V
V
Q
K
K
L
L
P
P
F
K
P
Q
V
T
S
E
V
D
T
R
Y
F
D
D
E
F
T
A
Q
S
I
T
------------------------------------
15
PsiBlast_PDB
73.32
45%
-117
- C1 -
4L43
1
KS6B1_HUMAN
A:
[10-343]
---------------------------------------------------------------------------------
R
G
P
E
---
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
N
---
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
-
N
A
K
D
T
A
H
T
K
A
E
R
N
I
L
-
E
-
E
V
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
-
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
-
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
-
G
H
V
K
L
T
D
F
G
L
C
K
E
S
--------------
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
-
P
P
F
---
T
G
E
---
N
R
K
K
-----
T
I
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
-----
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
--
G
P-
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
F
D
S
K
F
T
R
Q
T
P
V
---------------
S
A
N
Q
V
F
L
G
F
A
Y
V
---------
46
HHSearch
73.21
54%
-126
- C1 -
4EJN
3
AKT1_HUMAN
A:
[145-438]
-----------------------------------------------------------------------------------------
V
T
M
N
E
F
E
Y
L
K
L
L
G
K
G
-
T
F
G
K
V
I
L
V
K
-
E
---
K
A
---
T
G
R
Y
Y
A
M
K
I
L
K
K
E
V
I
V
---------------
V
L
Q
--
N
S
R
H
P
F
L
T
A
L
K
Y
S
F
Q
T
H
D
-
R
L
C
F
V
M
E
Y
A
N
G
G
E
L
F
F
H
L
S
R
-
E
R
V
F
S
E
D
R
A
R
F
Y
G
A
E
I
V
S
A
L
D
Y
L
H
S
E
K
N
V
V
Y
R
D
L
K
L
E
N
L
M
L
D
K
D
-
G
H
I
K
I
T
D
F
G
L
C
K
E
G
I
K
-----
K
--
T
-
F
C
G
T
P
E
Y
L
A
P
E
V
L
E
-----
D
N
---
D
Y
G
R
A
V
D
W
W
G
L
G
V
V
M
Y
E
M
M
C
G
R
-
L
P
F
---
Y
N
Q
---
D
H
E
K
-----
L
F
E
L
I
L
M
E
E
--
I
R
F
P
---
R
T
L
G
P
E
-----
A
K
S
L
L
S
G
L
L
K
K
D
P
K
Q
R
L
G
G
--
G
S-
E
-
D
A
K
E
I
M
Q
H
R
F
F
A
G
I
V
---
W
Q
H
V
Y
E
K
K
L
S
P
P
F
K
P
Q
V
T
S
E
T
D
T
R
Y
F
----------------------------------------------
37
HHSearch
73.06
45%
-105
- C1 -
4DC2
2
KPCI_MOUSE
A:
[49-387]
-----------------------------------------------------------------------------------------
L
G
L
Q
D
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
K
K
---
T
D
R
I
Y
A
M
R
V
V
K
K
E
L
V
N
------
I
D
W
V
Q
T
E
K
H
V
F
E
Q
-
A
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
-
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
-
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
R
P
G
D
T
T
S
--
T
-
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
-
S
P
F
---
D
I
V
GSN
T
E
D
Y
-----
L
F
Q
V
I
L
E
K
Q
--
I
R
I
P
---
R
S
L
S
V
K
-----
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
R
L
G
C
--
H
PQ
T
-
G
F
A
D
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
F
G
L
D
N
F
D
S
Q
F
T
N
E
P
V
Q
L
T
----
P
D
D
D
D
I
V
R
K
I
D
Q
S
E
F
E
G
F
E
Y
I
N
P
-------
19
PsiBlast_PDB
72.10
45%
-114
- C1 -
4L46
1
KS6B1_HUMAN
A:
[9-343]
--------------------------------------------------------------------------------
N
R
G
P
E
---
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
N
---
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
-
N
A
K
D
T
A
H
T
K
A
E
R
N
I
L
-
E
-
E
V
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
-
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
-
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
-
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
D
----
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
-
P
P
F
---
T
G
E
---
N
R
K
K
-----
T
I
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
-----
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
--
G
P-
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
---
E
E
D
V
S
Q
F
D
S
K
F
T
R
Q
T
P
V
------------------
Q
V
F
L
G
F
T
Y
V
---------
16
PsiBlast_PDB
71.59
45%
-110
- C1 -
4L44
1
KS6B1_HUMAN
A:
[10-343]
---------------------------------------------------------------------------------
R
G
P
E
---
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
N
---
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
-
N
A
K
D
T
A
H
T
K
A
E
R
N
I
L
-
E
-
E
V
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
-
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
-
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
-
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
-----
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
-
P
P
F
---
T
G
E
---
N
R
K
K
-----
T
I
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
-----
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
--
G
P-
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
S
E
E
D
V
S
Q
-
D
S
K
F
T
R
Q
T
---------------
S
E
S
A
N
Q
V
F
L
G
F
A
Y
V
---------
40
HHSearch
70.54
46%
-117
- C1 -
4L42
1
KS6B1_HUMAN
A:
[14-345]
----------------------------------------------------------------------------------------
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
N
---
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
N
A
-
K
D
T
A
H
T
K
A
E
R
N
I
L
E
E
--
V
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
-
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
-
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
-
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
D
G
T
V
T
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
-
P
P
F
---
T
G
E
---
N
R
K
K
-----
T
I
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
-----
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
--
G
P-
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
----------------------------------------
E
M
F
R
D
F
E
Y
I
A
D
-------
34
HHSearch
66.92
43%
-106
- C1 -
3TXO
1
KPCL_HUMAN
A:
[23-349]
--------------------------------------------------------------------------------------------
D
N
F
E
F
I
R
V
L
G
K
G
-
S
F
G
K
V
M
L
A
R
-
V
---
K
E
---
T
G
D
L
Y
A
V
K
V
L
K
K
D
V
I
L
Q
-
D
-
D
D
V
E
C
T
M
T
E
K
R
I
L
S
L
-
A
R
N
H
P
F
L
T
Q
L
F
C
C
F
Q
T
P
D
-
R
L
F
F
V
M
E
F
V
N
G
G
D
L
M
F
H
I
Q
K
-
S
R
R
F
D
E
A
R
A
R
F
Y
A
A
E
I
I
S
A
L
M
F
L
H
D
-
K
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
H
E
-
G
H
C
K
L
A
D
F
G
M
C
K
E
G
I
C
------------
G
T
P
D
Y
I
A
P
E
I
L
Q
-----
E
M
---
L
Y
G
P
A
V
D
W
W
A
M
G
V
L
L
Y
E
M
L
C
G
H
-
A
P
F
---
E
A
E
---
N
E
D
D
-----
L
F
E
A
I
L
N
D
E
--
V
V
Y
P
---
T
W
L
H
E
D
-----
A
T
G
I
L
K
S
F
M
T
K
N
P
T
M
R
L
G
S
--
L
TQ
G
-
G
E
H
A
I
L
R
H
P
F
F
K
E
I
D
---
W
A
Q
L
N
H
R
Q
I
E
P
P
F
R
P
R
I
K
S
R
E
D
V
S
N
F
D
P
D
F
I
K
E
E
P
V
L
T
P
I
D
E
---
G
-
H
L
P
M
I
N
Q
D
E
F
R
N
F
E
Y
V
S
P
-------
43
HHSearch
64.63
44%
-108
- C1 -
1RDQ
4
KAPCA_MOUSE
E:
[38-338]
-----------------------------------------------------------------------------------------
A
Q
L
D
Q
F
D
R
I
K
T
L
G
T
G
-
S
F
G
R
V
M
L
V
K
-
H
---
K
E
---
S
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
-
L
-
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
--
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
-
N
L
Y
M
V
M
E
Y
V
A
G
G
E
M
F
S
H
L
R
R
-
I
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
-
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
---
K
G
R
T
W
--
T
-
L
C
G
T
P
E
A
L
A
P
E
I
I
L
-----
S
K
---
G
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
-
P
P
F
---
F
A
D
---
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
K
--
V
R
F
P
---
S
H
F
S
S
D
-----
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
N
L-
K
--
N
-
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
---
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
-
Y
E
E
E
E
I
R
V
S
----------------------------------
51
HHSearch
62.36
48%
-118
* C1 *
4L3J
1
KS6B1_HUMAN
A:
[14-303]
----------------------------------------------------------------------------------------
K
I
R
P
E
C
F
E
L
L
R
V
L
G
K
G
-
G
Y
G
K
V
F
Q
V
R
-
K
VTG
A
N
---
T
G
K
I
F
A
M
K
V
L
K
K
A
M
I
V
R
N
A
-
K
D
T
A
H
T
K
A
E
R
N
I
L
E
E
--
V
K
H
P
F
I
V
D
L
I
Y
A
F
Q
T
G
G
-
K
L
Y
L
I
L
E
Y
L
S
G
G
E
L
F
M
Q
L
E
R
-
E
G
I
F
M
E
D
T
A
C
F
Y
L
A
E
I
S
M
A
L
G
H
L
H
Q
-
K
G
I
I
Y
R
D
L
K
P
E
N
I
M
L
N
H
Q
-
G
H
V
K
L
T
D
F
G
L
C
K
E
S
I
H
D
G
T
V
T
H
--
T
-
F
C
G
T
I
E
Y
M
A
P
E
I
L
M
-----
R
S
---
G
H
N
R
A
V
D
W
W
S
L
G
A
L
M
Y
D
M
L
T
G
A
-
P
P
F
---
T
G
E
---
N
R
K
K
-----
T
I
D
K
I
L
K
C
K
--
L
N
L
P
---
P
Y
L
T
Q
E
-----
A
R
D
L
L
K
K
L
L
K
R
N
A
A
S
R
L
G
A
--
G
P-
G
-
D
A
G
E
V
Q
A
H
P
F
F
R
H
I
N
---
W
E
E
L
L
A
R
K
V
E
P
P
F
K
P
L
L
Q
------------------------------------------------------
35
HHSearch
61.82
41%
-107
- C1 -
1XJD
1
A:
[16-335]
-------------------------------------------------------------------------------------------
I
E
D
F
I
L
H
K
M
L
G
K
G
-
S
F
G
K
V
F
L
A
E
-
F
---
K
K
---
T
N
Q
F
F
A
I
K
A
L
K
K
D
V
V
L
M
-
D
-
D
D
V
E
C
T
M
V
E
K
R
V
L
S
L
-
A
W
E
H
P
F
L
T
H
M
F
C
T
F
Q
T
K
E
-
N
L
F
F
V
M
E
Y
L
N
G
G
D
L
M
Y
H
I
Q
S
-
C
H
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
L
G
L
Q
F
L
H
S
-
K
G
I
V
Y
R
D
L
K
L
D
N
I
L
L
D
K
D
-
G
H
I
K
I
A
D
F
G
M
C
K
E
N
M
L
G
D
A
K
T
N
--
T
-
F
C
G
T
P
D
Y
I
A
P
E
I
L
L
-----
G
Q
---
K
Y
N
H
S
V
D
W
W
S
F
G
V
L
L
Y
E
M
L
I
G
Q
-
S
P
F
---
H
G
Q
---
D
E
E
E
-----
L
F
H
S
I
R
M
D
N
--
P
F
Y
P
---
R
W
L
E
K
E
-----
A
K
D
L
L
V
K
L
F
V
R
E
P
E
K
R
L
G
V
--
R
--
G
----
D
I
R
Q
H
P
L
F
R
E
I
N
---
W
E
E
L
E
R
K
E
I
D
P
------------------------------------------
Q
N
M
F
R
N
F
S
F
----------
20
PsiBlast_PDB
59.72
44%
-108
- C1 -
3ZH8
4
KPCI_HUMAN
A:
[6-337]
---------------------------------------------------------------------------------------------
D
F
D
L
L
R
V
I
G
R
G
-
S
Y
A
K
V
L
L
V
R
-
L
---
K
K
---
T
D
R
I
Y
A
M
K
V
V
K
K
E
L
V
N
D
-
D
-
E
D
I
D
W
V
Q
T
E
K
H
V
F
E
Q
-
A
S
N
H
P
F
L
V
G
L
H
S
C
F
Q
T
E
S
-
R
L
F
F
V
I
E
Y
V
N
G
G
D
L
M
F
H
M
Q
R
-
Q
R
K
L
P
E
E
H
A
R
F
Y
S
A
E
I
S
L
A
L
N
Y
L
H
E
-
R
G
I
I
Y
R
D
L
K
L
D
N
V
L
L
D
S
E
-
G
H
I
K
L
T
D
Y
G
M
C
K
E
G
L
R
P
G
D
T
T
S
--
T
-
F
C
G
T
P
N
Y
I
A
P
E
I
L
R
-----
G
E
---
D
Y
G
F
S
V
D
W
W
A
L
G
V
L
M
F
E
M
M
A
G
R
-
S
P
F
DIV----------
N
T
E
D
Y
L
F
Q
V
I
L
E
K
Q
--
I
R
I
P
---
R
S
L
S
V
K
-----
A
A
S
V
L
K
S
F
L
N
K
D
P
K
E
R
L
G
C
HP
Q
--
T
-
G
F
A
D
I
Q
G
H
P
F
F
R
N
V
D
---
W
D
M
M
E
Q
K
Q
V
V
P
P
F
K
P
N
I
S
G
E
-----------------
Q
L
T
P
D
D
D
D
I
-
V
R
K
I
D
-
Q
S
E
F
E
G
F
E
Y
----------
27
Fugue
56.37
39%
-104
- C1 -
1CDK
3
KAPCA_PIG
A:
[8-350]
------------------------------------------
K
G
S
E
Q
E
S
V
K
E
F
L
A
K
A
K
E
D
F
L
K
K
W
E
N
P
A
Q
N
T
A
------
H
-----------
L
D
Q
F
E
R
I
K
T
L
G
T
-G
S
F
G
R
V
M
L
V
K
H
K
---
E
T
---
G
-
N
H
F
A
M
K
I
L
D
K
Q
K
V
V
K
-
L
-
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V--
N
F
P
F
L
V
K
L
E
Y
S
F
K
D
N
-S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
I
-
G
R
F
S
E
P
H
A
R
F
Y
A
A
Q
I
V
L
T
F
E
Y
L
H
S
-
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
-Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
-
K
--
G
--
R
TW
T
-
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
-----
S
-KGY--
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
-Y
P
P
F
---
F
A
D
---
Q
P
I
Q
-----
I
Y
E
K
I
V
S
G
K
--
V
R
F
P
---
S
-----HF
S
S
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
N
L-
K
--
D
-
G
V
N
D
I
K
N
H
K
W
F
A
---TT
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
D
T
S
N
F
D
D
Y
E
E
E
E
I
R
V
S
I
---------
N
E
K
C
G
--
K
E
F
S
E
F
------------
53
HHSearch
47.34
46%
-113
- C1 -
3UBD
1
KS6A3_MOUSE
A:
[19-304]
---------------------------------------------------------------------------------------
E
K
A
D
P
S
Q
F
E
L
L
K
V
L
G
Q
G
-
S
F
G
K
V
F
L
V
K
-
K
---
I
S
GSD
A
R
Q
L
Y
A
M
K
V
L
K
K
A
T
L
-
K
-
V
-
R
D
R
V
------
D
I
L
V
--
E
V
N
H
P
F
I
V
K
L
H
Y
A
F
Q
T
E
G
-
K
L
Y
L
I
L
D
F
L
R
G
G
D
L
F
T
R
L
S
K
-
E
V
M
F
T
E
E
D
V
K
F
Y
L
A
E
L
A
L
A
L
D
H
L
H
S
-
L
G
I
I
Y
R
D
L
K
P
E
N
I
L
L
D
E
E
-
G
H
I
K
L
T
D
F
G
L
S
K
E
-----
K
K
A
Y
--
S
-
F
C
G
T
V
E
Y
M
A
P
E
V
V
N
-----
R
R
---
G
H
T
Q
S
A
D
W
W
S
F
G
V
L
M
F
E
M
L
T
G
T
-
L
P
F
---
Q
G
K
---
D
R
K
E
-----
T
M
T
M
I
L
K
A
K
--
L
G
M
P
---
Q
F
L
S
P
E
-----
A
Q
S
L
L
R
M
L
F
K
R
N
P
A
N
R
L
G
A
--
G
P-
D
-
G
V
E
E
I
K
R
H
S
F
F
S
T
I
D
---
W
N
K
L
Y
R
R
E
I
H
P
P
F
K
P
---------------------------------------------------------