@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00557_MAP11_: (2014-09-11 )
MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF
Atome Classification :
(19 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170....-...180.......190.......200......-.-210.......220.......230.......240.......250.......260.......270.......280.------......290.......300.......310.......320.......330.......340.......350.......360.......370.......380....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAA
V
E
T
R
V
CETDGCSSEAKLQCPT
C
I
K
LGIQGSYF
C
S
Q
E
C
FKGS
W
A
T
H
K
L
L
H
K
KAK
D
E
K
A
K
REVS
S
W
T
V
EGDINTDPWA
G
Y
R
Y
TGKLRPHYPLMPTRPV
P
S
Y
IQRPDYADHPLGM
S
E
S
E
Q
A
LKGT
S
Q
I
K
L
LSSED
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
MIKPGV
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
NCYPSPLNYYNF
P
K
S
C
C
T
S
V
N
E
V
I
CHGIPDR-R-PLQEG
D
I
V
N
V
D
I
T
L
Y
RNGYHGDLN
E
T
F
F
V
G
EVD
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
AVKPG
V
R
Y
R
E
L
G
N
I
I
Q
K
H
AQAN------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
HTAPNVPHYAKNK
A
V
G
V
MKSG
H
V
F
T
I
E
P
M
I
CEGGWQDETWPDG
W
T
A
VTRDGKRSA
Q
F
E
H
T
L
L
V
TDT
G
C
E
I
L
T
R
R
LDSARPHFMSQF
11
PsiBlast_PDB
99.33
100%
-102
- C1 -
2NQ7
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
13
PsiBlast_PDB
99.27
100%
-100
- C1 -
4IKS
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
8
PsiBlast_PDB
99.27
100%
-101
- C1 -
2B3L
3
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
14
PsiBlast_PDB
99.10
100%
-103
- C1 -
4IKT
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
4
PsiBlast_PDB
99.01
100%
-102
- C1 -
4FLK
1
MAP11_HUMAN
A:
[2-305]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
2
PsiBlast_PDB
98.93
100%
-102
- C1 -
4FLI
1
MAP11_HUMAN
A:
[2-305]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
15
PsiBlast_PDB
98.80
100%
-101
- C1 -
4IKU
1
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
5
PsiBlast_PDB
98.78
100%
-102
- C1 -
4FLL
1
MAP11_HUMAN
A:
[2-305]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
3
PsiBlast_PDB
98.78
100%
-102
- C1 -
4FLJ
1
MAP11_HUMAN
A:
[2-305]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
17
PsiBlast_PDB
98.69
100%
-101
- C1 -
4HXX
1
MAP11_HUMAN
A:
[1-304]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
16
PsiBlast_PDB
98.66
100%
-101
- C1 -
2G6P
3
MAP11_HUMAN
A:
[1-304]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
10
PsiBlast_PDB
98.55
100%
-102
- C1 -
2NQ6
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
12
PsiBlast_PDB
98.41
100%
-103
- C1 -
4IKR
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
1
PsiBlast_PDB
98.28
100%
-101
- C1 -
4IU6
1
MAP11_HUMAN
A:
[81-384]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
6
PsiBlast_PDB
98.01
100%
-101
- C1 -
2B3H
2
MAP11_HUMAN
A:
[26-329]
--------------------------------------------------------------------------------
Y
R
Y
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Q
R
P
D
Y
A
D
H
P
L
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
E
D
I
E
G
M
R
L
V
C
R
L
A
R
E
V
L
D
V
A
A
G
M
I
K
P
G
V
T
T
E
E
I
D
H
A
V
H
L
A
C
I
A
-
R
N
C
Y
P
S
P
L
N
Y
Y
N
F
P
K
S
C
C
T
S
V
N
E
V
I
C
H
G
I
P
D
R
-
R
-
P
L
Q
E
G
D
I
V
N
V
D
I
T
L
Y
R
N
G
Y
H
G
D
L
N
E
T
F
F
V
G
E
V
D
D
G
A
R
K
L
V
Q
T
T
Y
E
C
L
M
Q
A
I
D
A
V
K
P
G
V
R
Y
R
E
L
G
N
I
I
Q
K
H
A
Q
A
N
------
G
F
S
V
V
R
S
Y
C
G
H
G
I
H
K
L
F
H
T
A
P
N
V
P
H
Y
A
K
N
K
A
V
G
V
M
K
S
G
H
V
F
T
I
E
P
M
I
C
E
G
G
W
Q
D
E
T
W
P
D
G
W
T
A
V
T
R
D
G
K
R
S
A
Q
F
E
H
T
L
L
V
T
D
T
G
C
E
I
L
T
R
R
L
D
S
A
R
P
H
F
M
S
--
35
HHSearch
75.28
49%
-89
- C1 -
3PKA
1
MAP12_MYCTU
A:
[4-284]
-----------------------------------------------------------------------------------
R
T
A
L
S
P
-
G
V
L
S
P
T
R
P
V
P
N
W
I
A
R
P
E
Y
V
G
K
--
P
A
A
Q
----
E
--
G
S
E
P
W
V
Q
T
P
E
V
I
E
K
M
R
V
A
G
R
I
A
A
G
A
L
A
E
A
G
K
A
V
A
P
G
V
T
T
D
E
L
D
R
I
A
H
E
Y
L
V
D
-
N
G
A
Y
P
S
T
L
G
Y
K
G
F
P
K
S
C
C
T
S
L
N
E
V
I
C
H
G
I
P
D
S
-
T
-
V
I
T
D
G
D
I
V
N
I
D
V
T
A
Y
I
G
G
V
H
G
D
T
N
A
T
F
P
A
G
D
V
A
D
E
H
R
L
L
V
D
R
T
R
E
A
T
M
R
A
I
N
T
V
K
P
G
R
A
L
S
V
I
G
R
V
I
E
S
Y
A
N
R
F
------
G
Y
N
V
V
R
D
F
T
G
H
G
I
G
T
T
F
H
N
G
L
V
V
L
H
Y
D
Q
P
A
V
E
T
I
M
Q
P
G
M
T
F
T
I
E
P
M
I
N
L
G
A
L
D
Y
E
I
W
D
D
G
W
T
V
V
T
K
D
R
K
W
T
A
Q
F
E
H
T
L
L
V
T
D
T
G
V
E
I
L
T
C
-------------
41
HHSearch
70.96
48%
-98
* C1 *
2GG2
1
MAP1_ECOLI
A:
[2-250]
-------------------------------------------------------------------------------------------------------------------------------
I
S
I
K
T
P
E
D
I
E
K
M
R
V
A
G
R
L
A
A
E
V
L
E
M
I
E
P
Y
V
K
P
G
V
S
T
G
E
L
D
R
I
C
N
D
Y
I
V
N
E
Q
H
A
V
S
A
C
L
G
Y
H
G
Y
P
K
S
V
C
I
S
I
N
E
V
V
C
H
G
I
P
D
D
A
K
-
L
L
K
D
G
D
I
V
N
I
D
V
T
V
I
K
D
G
F
H
G
D
T
S
K
M
F
I
V
G
K
P
T
I
M
G
E
R
L
C
R
I
T
Q
E
S
L
Y
L
A
L
R
M
V
K
P
G
I
N
L
R
E
I
G
A
A
I
Q
K
F
V
E
A
E
------
G
F
S
V
V
R
E
Y
C
G
H
G
I
G
R
G
F
H
E
E
P
Q
V
L
H
Y
D
S
R
E
T
N
V
V
L
K
P
G
M
T
F
T
I
E
P
M
V
N
A
G
K
K
E
I
R
T
M
K
D
G
W
T
V
K
T
K
D
R
S
L
S
A
Q
Y
E
H
T
I
V
V
T
D
N
G
C
E
I
L
T
L
R
------------
47
HHSearch
66.70
33%
-93
- C1 -
3TAV
1
?
A:
[32-284]
-------------------------------------------------------------------------------------------------------------------------------
V
E
Q
R
T
P
G
E
L
D
A
M
A
A
A
G
S
I
V
G
A
A
L
V
A
V
R
D
A
A
K
A
G
V
S
T
L
E
L
D
Q
V
A
E
S
V
I
R
E
-
A
G
A
V
P
S
F
L
G
Y
H
G
F
P
A
S
I
C
S
S
V
N
D
Q
V
V
H
G
I
P
S
A
-
T
A
V
L
A
D
G
D
L
V
S
I
D
C
G
A
I
L
D
G
W
H
G
D
S
A
W
T
F
A
V
G
T
V
I
P
S
D
E
A
L
S
E
A
T
R
L
S
M
E
A
G
I
A
A
M
I
P
G
N
R
L
T
D
V
S
H
A
I
E
L
G
T
R
A
A
E
K
Q
F
D
R
A
F
G
I
V
D
G
Y
G
G
H
G
I
G
R
S
M
H
L
D
P
F
L
P
N
E
G
A
P
G
K
G
P
L
L
A
V
G
S
V
L
A
I
E
P
M
L
T
L
G
T
T
Q
T
R
V
L
A
D
D
W
T
V
V
T
T
D
G
S
R
A
A
H
W
E
H
T
V
A
V
T
E
A
G
P
R
I
L
T
M
-------------
44
HHSearch
65.78
34%
-94
- C1 -
3TB5
1
?
A:
[3-248]
--------------------------------------------------------------------------------------------------------------------------------
T
L
K
S
P
R
E
I
E
M
M
D
E
S
G
E
L
L
A
D
V
H
R
H
L
R
T
F
I
K
P
G
I
T
S
W
D
I
E
V
F
V
R
D
F
I
E
S
-
H
G
G
V
A
A
Q
I
G
Y
E
G
Y
K
Y
A
T
C
C
S
I
N
D
E
I
C
H
G
F
P
R
K
-
K
-
V
L
K
D
G
D
L
I
K
V
D
M
C
V
D
L
K
G
A
I
S
D
S
C
W
S
Y
V
V
G
E
S
T
P
E
I
D
R
L
M
E
V
T
K
K
A
L
Y
L
G
I
E
Q
A
Q
V
G
N
R
I
G
D
I
G
H
A
I
Q
T
Y
V
E
G
E
------
G
Y
G
V
V
R
D
F
V
G
H
G
I
G
P
T
I
H
E
S
P
M
I
P
H
Y
G
E
A
G
K
G
L
R
L
K
E
G
M
V
I
T
I
E
P
M
V
N
T
G
T
W
R
M
K
M
D
P
N
G
W
T
A
Y
T
E
D
G
G
L
S
C
Q
Y
E
H
S
L
A
I
T
K
E
G
P
R
I
L
T
S
Q
------------