@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00603_PA_I34: (2014-09-12 )
MEDFVRQCFNPMIVELAEKTMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRKLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPLRLPNGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPNVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFDDCKDVGDLKQYDSDEPELRSLASWIQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTSEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLIRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEESSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALS
Atome Classification :
(40 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
T
M
K
EYGEDLKIE
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
YS
D
F
H
F
INEQG
E
S
I
I
V
E
LGD
P
N
A
L
L
K
H
R
F
E
I
IEGRDRT
M
A
W
T
V
V
N
S
I
CNTTGAEKPKFL
P
D
L
YDYKE
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
LEKANKIKSEK
T
H
I
H
I
F
S
FTG
E
E
MATKADYTL
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
SRG
L
W
D
S
F
R
Q
SER
G
E
E
T
I
E
E
R
F
E
I
T
G
T
M
R
K
L
A
DQSLPP
N
F
S
S
L
E
N
F
R
A
Y
VDGFEPNG
Y
I
E
G
K
L
S
Q
M
S
K
E
V
N
A
R
I
E
P
F
L
KTTPRPLRLPNGP
P
C
S
Q
R
S
K
F
L
L
M
D
A
L
K
L
SIEDPSHEGEG
I
P
L
Y
D
A
I
K
C
M
R
T
FFGWKEPNVVKPHEKGIN
P
N
Y
L
L
S
W
K
Q
V
L
A
E
L
Q
DIE
N
E
EKIPKTKNM
K
K
T
S
Q
L
K
W
A
LGENMAPEKV
D
F
D
DCK
D
V
G
D
L
K
QYDSD
E
P
E
L
R
S
L
A
S
W
I
Q
N
E
F
N
K
A
CELTDSS
W
I
E
L
D
E
IGE
D
V
A
P
I
E
H
I
A
S
M
R
R
N
Y
F
T
S
E
V
S
H
C
R
A
T
E
Y
I
M
KG
V
Y
I
N
T
A
L
LNASCAAMDD
F
Q
L
I
P
M
I
S
K
CRTKEGRRKT
N
L
Y
G
F
I
IKGRSHLRND
T
D
V
V
N
F
V
S
M
E
F
SLTDPRLEPHKW
E
K
Y
C
V
L
E
I
G
D
M
L
I
R
S
A
I
G
QVSR
P
M
F
L
Y
V
RTNGT
S
K
I
K
M
K
W
G
M
E
M
R
R
C
L
L
Q
S
L
Q
Q
I
E
S
M
I
E
A
E
SSV
K
E
K
D
M
T
K
E
F
F
ENKSETWPIGESPKGV
E
E
S
S
I
G
K
V
C
R
T
L
L
A
K
S
V
F
N
S
L
YASPQLEGFSAES
R
K
L
L
L
I
V
Q
A
L
RDNLEPGTF
D
L
G
G
L
Y
E
A
I
E
E
C
LIND
P
W
V
L
L
N
A
S
W
F
N
S
F
L
T
H
ALS
49
PsiBlast_CBE
62.02
95%
-87
- C10 -
4AVG
1
?
D:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
-
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
61.97
95%
-89
- C10 -
4AVG
1
?
C:
[7-202]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
-
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
-
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
61.90
95%
-84
- C10 -
4AVL
1
?
D:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.88
95%
-82
- C10 -
4M5O
4
?
A:
[38-232]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
61.46
95%
-83
- C10 -
4M5U
1
?
A:
[38-232]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
61.41
95%
-80
- C10 -
4AWG
1
?
B:
[7-200]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
------
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.26
95%
-80
- C10 -
4M4Q
1
?
A:
[38-232]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
61.19
95%
-87
- C10 -
4AVL
1
?
B:
[7-202]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
-----
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
--
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
60.93
95%
-84
- C10 -
4AVL
1
?
C:
[7-202]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
------
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
--
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
60.68
95%
-84
- C10 -
4AVL
1
?
A:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
-----------------
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
-
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
60.48
95%
-82
- C10 -
4AWH
1
?
A:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
60.40
95%
-84
- C10 -
4AWH
1
?
C:
[7-201]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
----
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
60.36
95%
-85
- C10 -
4AWG
1
?
C:
[7-201]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
S
G
D
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.35
94%
-81
- C10 -
3HW3
1
PA_I96A0
A:
[6-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
-------------------------
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
60.24
95%
-80
- C10 -
4AWH
1
?
D:
[7-202]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
D
E
R
G
E
S
I
I
V
E
--------
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
60.24
94%
-74
- C10 -
3HW4
2
PA_I96A0
A:
[6-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
------------------------
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
60.18
95%
-91
- C10 -
4AWF
1
?
A:
[7-204]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
-----
S
I
I
V
E
---
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
---
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
59.94
95%
-79
- C10 -
3HW5
1
PA_I96A0
A:
[6-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
-------------------------
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
59.72
95%
-94
- C10 -
4AWF
1
?
C:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
-----
S
I
I
V
-----
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
---
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
59.49
95%
-92
- C10 -
4AWF
1
?
B:
[7-203]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
H
F
I
-----
S
I
I
V
E
---
P
N
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
---
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
59.35
94%
-79
- C10 -
3HW4
1
PA_I96A0
D:
[6-202]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
-------------------------
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
58.32
86%
-71
- C10 -
4E5J
2
?
C:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
58.24
86%
-76
- C10 -
4AWK
1
?
A:
[7-180]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
---------------------
G
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
K
-
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
58.24
90%
-91
- C10 -
4AWM
2
?
A:
[7-190]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
F
G
-----------------
A
L
L
K
H
R
F
E
I
I
E
G
R
D
R
I
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
I
Y
Y
L
E
K
A
N
K
I
--
E
K
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
S
L
W
D
S
F
R
Q
S
E
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
58.18
86%
-68
- C10 -
4E5G
2
?
B:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
57.97
86%
-67
- C10 -
4E5J
2
?
A:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
57.91
86%
-68
- C10 -
4E5G
1
?
D:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
57.88
86%
-70
- C10 -
4E5G
2
?
C:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
57.87
86%
-68
- C10 -
4E5J
2
?
B:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
57.85
86%
-72
- C10 -
4E5J
2
?
D:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
57.81
86%
-67
- C10 -
4E5I
1
?
A:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
57.81
86%
-65
- C10 -
4E5L
1
?
C:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
57.79
86%
-70
- C10 -
4E5L
1
?
D:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
57.74
86%
-76
- C10 -
4E5I
1
?
B:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
57.72
86%
-66
- C10 -
4E5I
1
?
C:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
57.63
86%
-71
- C10 -
4E5H
1
?
D:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
57.57
86%
-72
- C10 -
4E5I
1
?
D:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
57.54
86%
-69
- C10 -
4E5L
1
?
A:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
57.44
86%
-66
- C10 -
4E5G
2
?
A:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
57.29
86%
-73
- C10 -
4E5L
1
?
B:
[1-178]
M
E
D
F
V
R
Q
C
F
N
P
M
I
V
E
L
A
E
K
A
M
K
E
Y
G
E
D
P
K
I
E
T
N
K
F
A
A
I
C
T
H
L
E
V
C
F
M
Y
S
D
-------
G
G
S
------------
K
H
R
F
E
I
I
E
G
R
D
R
T
M
A
W
T
V
V
N
S
I
C
N
T
T
G
V
E
K
P
K
F
L
P
D
L
Y
D
Y
K
E
N
R
F
I
E
I
G
V
T
R
R
E
V
H
T
Y
Y
L
E
K
A
N
K
I
K
S
E
E
T
H
I
H
I
F
S
F
T
G
E
E
M
A
T
K
A
D
Y
T
L
D
E
E
S
R
A
R
I
K
T
R
L
F
T
I
R
Q
E
M
A
S
R
G
L
W
D
S
F
R
Q
S
E
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------