Atome 2 Filter

@TOME V2.3
(Nov 2016)

Ref. - - Doc.

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Sequence color : MutatedHelixStrandConserved

Query sequence : O10A2_HUMAN: (2016-01-11 )
MSFSSLPTEIQSLLFLTFLTIYLVTLMGNCLIILVTLADPMLHSPMYFFLRNLSFLEIGFNLVIVPKMLGTLLAQDTTISFLGCATQMYFFFFFGVAECFLLATMAYDRYVAICSPLHYPVIMNQRTRAKLAAASWFPGFPVATVQTTWLFSFPFCGTNKVNHFFCDSPPVLRLVCADTALFEIYAIVGTILVVMIPCLLILCSYTHIAAAILKIPSAKGKNKAFSTCSSHLLVVSLFYISLSLTYFRPKSNNSPEGKKLLSLSYTVMTPMLNPIIYSLRNNEVKNALSRTVSKALALRNCIP

Atome Classification :

	(20 SA)									--------------------------.....--------------....10.....-...20........30........40........50........60...-.....70........--80........90........100.......110.......120.......130........140.-......---------150..-----.....160.......170....----....180.......190.......200.----........210.-------------.---------.....--------------------220------.---........230......-------.240.......----250-.-.--.---..-.-..260.--..--.--.....270....--...280.......290----------------.......300.-------------------------------
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		--------------------------MSFSS--------------LPTEIQSLLFL-TFLTIYLVTLMGNCLIILVTLADPMLHSPMYFFLRNLSFLEIGFNLVI-VPKMLGTLLAQDTTI--SFLGCATQMYFFFFFGVAECFLLATMAYDRYVAICSPLHYPVIMNQRTRAK-LAAASWFPGFPVA-TVQTTW---------LFSFP-----FCGTNKVNHFFCDSPP-VLRLV----CADTALFEIYAIVGTILVVMIPCLL--I----LCSYTHIAAAIL-------------K---------IPSAK--------------------G--------K---NKAFSTCSSHLLVVSLF-------YISLSLTYFRP----KS--N-N--S---PE-G-KKL--L--SL--S--YTVMTPMLNPII--YSLRNNEVKNALSRTV----------------SKALALRNCIP-------------------------------
6	PsiBlast_PDB	92.18	22%	-152	- C3 -	3VG9		?	A:[6-309]	--------------------------------------------------SSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQ-------SQ-----GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVLR-----------------------------------
7	PsiBlast_PDB	91.77	22%	-153	- C3 -	3VGA		AA2AR_HUMAN	A:[6-308]	--------------------------------------------------SSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQ-------SQ-----GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVL------------------------------------
10	PsiBlast_PDB	90.99	22%	-152	- C3 -	4UG2		?	A:[6-309]	--------------------------------------------------SSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLA-IP--FAIAISTGFCA--ACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQ-----GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQL--------------------------------A--------RSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVLR-----------------------------------
11	PsiBlast_PDB	90.85	22%	-151	- C3 -	4UHR		AA2AR_HUMAN	A:[6-313]	--------------------------------------------------SSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLA-IP--FAIAISTGFCA--ACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKA--------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC----H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVLRQQEP-------------------------------
8	PsiBlast_PDB	90.60	22%	-148	- C3 -	2YDO		?	A:[6-313]	--------------------------------------------------SSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLA-IP--FAIAISTGFCA--ACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQ-----GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQLKQMES-------------------------------------TL-QKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVLRQQEP-------------------------------
9	PsiBlast_PDB	88.72	22%	-151	- C3 -	2YDV		?	A:[3-313]	-----------------------------------------------IMGSSVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSAAAADILVGVLA-IP--FAIAISTGFCA--ACHGCLFIACFVLVLTASSIFSLLAIAIDRYIAIRIPLRYNGLVTG-TRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKAHSQ-----GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFLAAR-------------RQLKQMESQ------------------------------------STLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LSHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRSHVLRQQEP-------------------------------
1	PsiBlast_PDB	88.20	21%	-150	- C3 -	3PWH		?	A:[7-305]	---------------------------------------------------SVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAG-IIAICWVLSFAIGLTPMLGWNNCGQP-------------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFAAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LAHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRS---------------------------------------
2	PsiBlast_PDB	87.63	21%	-155	- C3 -	3REY		AA2AR_HUMAN	A:[7-305]	---------------------------------------------------SVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAG-IIAICWVLSFAIGLTPMLGWNNCGQP-------------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFAAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LAHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRS---------------------------------------
3	PsiBlast_PDB	87.57	21%	-154	- C3 -	3RFM		AA2AR_HUMAN	A:[7-305]	---------------------------------------------------SVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAG-IIAICWVLSFAIGLTPMLGWNNCGQP-------------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFAAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LAHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRS---------------------------------------
4	PsiBlast_PDB	87.49	21%	-156	- C3 -	3UZA		AA2AR_HUMAN	A:[7-305]	---------------------------------------------------SVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAG-IIAICWVLSFAIGLTPMLGWNNCGQP-------------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFAAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LAHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRS---------------------------------------
5	PsiBlast_PDB	87.39	21%	-156	- C3 -	3UZC		AA2AR_HUMAN	A:[7-305]	---------------------------------------------------SVYIT-VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLA-IP--FAITISTGFCA--ACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAG-IIAICWVLSFAIGLTPMLGWNNCGQP-------------GCGEGQVACLFEDVVP-MNYMV---------YFNFFA------CVLVPLLL--M----LGVYLRIFAAAR-------------RQLKQMESQPLPGER--------------------A--------RSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCP----DC--S-H--A---PL-W-LMY--L--AI--V--LAHTNSVVNPFI--YAYRIREFRQTF-RKI----------------IRS---------------------------------------
32	HHSearch	79.37	17%	-128	* C3 *	2KS9		NK1R_HUMAN	A:[35-325]	-----------------------------------------------------WAA-AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFN-TVVNFTYAVHNEWYY--GLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRL--SATATKV-VICVIWVLALLLA-FPQGYY---------S-T-------T-E-TMPSRVVCMIEW-PEH-------PNKIYEKVYHICVTVLIYFLPLLV--I----GYAYTVVGITLW-------------A---------SEIPGDSSDRYHEQVS---------A--------K---RKVVKMMIVVVCTFAIC-------WLPFHIFFLLP----YI--N-P--DLYLKKFI-QQV--Y--LA--IMWLAMSSTMYNPII--YCCLNDRFRLGFKHAF----------------RCCPFISAGDY-------------------------------
34	HHSearch	78.87	17%	-127	- C3 -	2Z73		OPSD_TODPA	A:[32-334]	------------------------------------------------AVYYSLGI-FIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIF--GFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFI-MIIFVWLWSVLWA-IGPIFG---------WGA--------YTL-EGVLCNCSFDY-IS---------RDSTTRSNILCMFILGFFGPILI--I----FFCYFNIVMSVS-------------N---------HEKEMAAMAKRLNAKELRKAQAGANA--------E---MRLAKISIVIVSQFLLS-------WSPYAVVALLA----QF--G-PL-E---WV-T-PYAAQL--PV--M--FAKASAIHNPMI--YSVSHPKFREAISQTF----------------PWVLTCCQFDD-------------------------------
41	Fugue	72.49	15%	-122	- C3 -	1F88		OPSD_BOVIN	A:[1-348]	MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYL--------------AEPWQFSMLAA-YMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLHGYFVF--GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMG-VAFTWVMALACAA-PPLVGW---------SRYIPEGMQCSCGID----YYTPHEE-TNNES----FVIYMFVVHFIIPLIVIFFCYGQLV--F------TVKEAAASAT-------------T---------QKAEK--------------------E--------V---TRMVIIMVIAFLICWLP-------YAGVAFYIFTH----QG--S-D--F---GP-I-FMT--I--PA--F--FAKTSAVYNPVI--YIMMNKQFRNCMVTTL----------------CCGKNPSTTVSKTETSQVAPA---------------------
31	HHSearch	72.11	15%	-118	- C3 -	1U19		OPSD_BOVIN	A:[41-328]	---------------------------------------------------SMLAA-YMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLHGYFVF--GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIM-GVAFTWVMALACA-APPLVG---------WSRY--------IP-EGMQCSCGIDY-YTP-------HEETNNESFVIYMFVVHFIIPLIV--I----FFCYGQLVFTVK-------------E---------AAAQQ--------------------QESATTQKAE---KEVTRMVIIMVIAFLIC-------WLPYAGVAFYI----FT--H-Q--G---SD-FGPIF--MTIPA--F--FAKTSAVYNPVI--YIMMNKQFRNCMVTTL----------------CCGKNPLGDDE-------------------------------
29	HHSearch	68.62	16%	-113	- C3 -	2LNL	-	CXCR1_HUMAN	A:[37-323]	------------------------------------------------LNKYVVII-AYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFAL-T-LPIWAASKV-NGWIF--GTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLT-QKRHLVKF-VCLGCWGLSMNLS-LPFFLF---------RQA--------YHP-NNSSPVCYEVL-GND--------TAKWRMVLRILPHTFGFIVPLFV--M----LFCYGFTLRTLF-------------K---------AHM-G--------------------Q--------K---HRAMRVIFAVVLIFLLC-------WLPYNLVLLADTLMRTQVIQESCERR--NN-I-GRA--L--DATEI--LGFLHSCLNPII--YAFIGQNFRHGFLKIL----------------AMHG--------------------------------------
40	Fugue	68.53	16%	-107	- C3 -	1U19		OPSD_BOVIN	A:[4-349]	--------------MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAA-YMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTSLHGYFVF--GPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFR-FGENHAIM-GVAFTWVMALACAAPPLVGW---------SRYIPEGMQCSCGID----YYTPHEE-TNNES----FVIYMFVVHFIIPLIVIFFCYGQLVFTV----KEAAAQQQESAT-------------T---------QKAEK--------------------E--------V---TRMVIIMVIAFLICWLP-------YAGVAFYIFTH----QG--S-D--F---GP-I-FMT--I--PA--F--FAKTSAVYNPVI--YIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA-------------------------------
13	PsiBlast_PDB	68.25	25%	-158	- C3 -	2YCW		ADRB1_MELGA	A:[3-219]	----------------------------AEL--------------LSQQWEAGMSL-LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLV-VP-FGATLVVRGTWLWGSFL-CELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMT-RARAK-V-------------IICTVW---------AISAL-----VSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLI--MIFVALRVYREAKEQIR-------------K---------IDRAS--------------------K--------R---KRVMLMREHKALKTLGI-------IMGVFTLCWLP----FF--L-V--N---IV-N-VFN--R--DL--V--PDWLFVAFNWLG--YANSAMNPIIYCRSPD----------------FRKAFKRLLAF-------------------------------
15	PsiBlast_PDB	67.31	25%	-162	- C3 -	2YCZ		ADRB1_MELGA	A:[9-219]	------------------------------------------------QWEAGMSL-LMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLV-VP-FGATLVVRGTWLWGSFL-CELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMT-RARAK-V-------------IICTVW---------AISAL-----VSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLI--MIFVALRVYREAKEQIR-------------K---------IDRAS--------------------K--------R---KRVMLMREHKALKTLGI-------IMGVFTLCWLP----FF--L-V--N---IV-N-VFN--R--DL--V--PDWLFVAFNWLG--YANSAMNPIIYCRSPD----------------FRKAFKRLLAF-------------------------------
43	Fugue	67.13	15%	-124	- C3 -	4XNV		P2RY1_HUMAN (first)	A:[38-382]	-------------------------SFKCAL--------------TKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTL-PALIFYYFNKTDWIF--GDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPKSL-----GRLKKK-NAICISVLVWLIV-VVAISP---------ILFYS-----GTGVRKNKTITCYDTT-SDEY--------LRSYFIYSMCTTVAMFCVPLVL--I----LGCYGLIVRALIYKMKKYTCTVCGYI---------YNPED--------------------G--------D---PDNGVNPGTDFKDIVCP-------LCGVGKDQFEE----VE--E--------PL-R-RKS--I--YL--V--IIVLTVFAVSYIPFHVMKTMNLRARLDFQT----------------PAMCAFNDRVYATYQVTRGLASLNSCVNPILYFLAGDTFRRR