Atome 2 Filter

@TOME V2.3
(Nov 2016)

Ref. - - Doc.

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Sequence color : MutatedHelixStrandConserved

Query sequence : O10K1_HUMAN: (2016-01-11 )
MEQVNKTVVREFVVLGFSSLARLQQLLFVIFLLLYLFTLGTNAIIISTIVLDRALHTPMYFFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFLGCAIQMFSFLFFGSSHSFLLAAMGYDRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTVSLVTTSLVFHLPFHSSNQLHHFFCDISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLILVSYIRIISAILKIPSSVGRYKTFSTCASHLIVVTVHYSCASFIYLRPKTNYTSSQDTLISVSYTILTPLFNPMIYSLRNKEFKSALRRTIGQTFYPLS

Atome Classification :

	(20 SA)									----------------------.........10....---------------....20-.........30--------.........40........50-----.--.......60....-------------....70......-..80.-----.......90........100--....------....110-......-----------------------.120.......130.......140.......150.......160.......-170.......180.........190.-----.--.....200........-.----210---------........220.....---------.-------.-----230----------.--------------------.-----------.---..-...240.......250..--------------.....260.---.-.---.-.----..-270.......--280..--.....290.......300.......310.-------------------
		(Atome)	(Ident)	(Tito)	(Num)		(Ligand)	(Uniprot)		----------------------MEQVNKTVVREFVVL---------------GFSSL--ARLQQLLFVI---------FLLLYLFTLGTNAIIISTIVL-----D--RALHTPMYFFLAI-------------LSCSEICYTFVI-VPKML-----VDLLSQKKTISFLGCAIQM---FSFL------FFGSSHS-FLLAAM-----------------------GYDRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTVSLVTTSLVFHLPFH-SSNQLHHFFCD--ISPVLKLASQHSG-----F--SQLVIF--MLGVFALV-I----PL----------LLILVSYIRIISAILK---------I-------P-----SS-----------V--------------------G-----------R---YK-TFSTCASHLIVVTVHYSC--------------ASFIYLRPK---T-N---Y-T----SS-QDTLISVSYT--ILTPL--FNPMIYSLRNKEFKSALRRTIGQTFYPLS-------------------
1	PsiBlast_PDB	89.73	22%	-148	- C2 -	3PWH		?	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADILVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLAQSSI-FSLLAI-----------------------AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQP---------GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFAAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSAAIIAGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLA--HTNSV--VNPFIYAYRIREFRQTFRKIIRS-------------------------
2	PsiBlast_PDB	89.55	22%	-151	- C2 -	3REY		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADILVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLAQSSI-FSLLAI-----------------------AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQP---------GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFAAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSAAIIAGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLA--HTNSV--VNPFIYAYRIREFRQTFRKIIRS-------------------------
4	PsiBlast_PDB	89.19	22%	-150	- C2 -	3UZA		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADILVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLAQSSI-FSLLAI-----------------------AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQP---------GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFAAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSAAIIAGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLA--HTNSV--VNPFIYAYRIREFRQTFRKIIRS-------------------------
5	PsiBlast_PDB	88.66	22%	-151	- C2 -	3UZC		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADILVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLAQSSI-FSLLAI-----------------------AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQP---------GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFAAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSAAIIAGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLA--HTNSV--VNPFIYAYRIREFRQTFRKIIRS-------------------------
3	PsiBlast_PDB	88.37	22%	-151	- C2 -	3RFM		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADILVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLAQSSI-FSLLAI-----------------------AIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQP---------GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFAAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSAAIIAGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLA--HTNSV--VNPFIYAYRIREFRQTFRKIIRS-------------------------
13	PsiBlast_PDB	86.32	22%	-141	- C2 -	4UHR		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------AAAADILVGVLA-IPFAI-----A--ISTGFCAACHGCLFIA---CFVL------VLTASSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQP-KEGKA---GCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-----H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVLRQQ-------------------
10	PsiBlast_PDB	85.70	22%	-142	- C2 -	2YDO		?	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------AAAADILVGVLA-IPFAI-----A--ISTGFCAACHGCLFIA---CFVL------VLTASSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQP-KEGKAHSQGCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQLKQMES---------------------------------------------------------------TL-QK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVLRQQ-------------------
12	PsiBlast_PDB	85.50	22%	-148	- C2 -	4UG2		?	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------AAAADILVGVLA-IPFAI-----A--ISTGFCAACHGCLFIA---CFVL------VLTASSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQP-KEGKAHSQGCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQL-------------------------------------------------------A-----------RSTLQK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVLR---------------------
9	PsiBlast_PDB	85.16	22%	-147	- C2 -	3VGA		AA2AR_HUMAN	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADIAVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLTQSSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQ--------SQGCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVL----------------------
11	PsiBlast_PDB	84.25	22%	-147	- C2 -	2YDV		?	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------AAAADILVGVLA-IPFAI-----A--ISTGFCAACHGCLFIA---CFVL------VLTASSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQP-KEGKAHSQGCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQLKQMESQ--------------------------------------------------------------STLQK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVLRQQ-------------------
8	PsiBlast_PDB	83.63	22%	-149	- C2 -	3VG9		?	A:[24-303]	-----------------------------------------------------------------------------------------NVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADIAVGVLA-IPFAI-----T--ISTGFCAACHGCLFIA---CFVL------VLTQSSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQ--------SQGCG--EGQVACLFEDVVP-----M--NYMVYF----NFFACVLV----PL----------LLMLGVYLRIFLAARRQLKQMESQPL-------P-----GE-----------R--------------------A-----------RSTLQK-EVHAAKSLAIIVGLFALCWLPLHII-------NCFTFFCPD---C-S---H-A----PL-WLMYLAIVLS--HTNSV--VNPFIYAYRIREFRQTFRKIIRSHVLR---------------------
39	Fugue	82.42	17%	-129	- C2 -	1F88		OPSD_BOVIN	A:[1-348]	-----------MNGTEGPNFYVPFSNKTGVVRSPFEA---------------PQYYLAEPWQFSMLAAY---------MFLLIMLGFPINFLTLYVTVQ-----H--KKLRTPLNYILLN-------------LAVADLFMVFGG-FTTTL-----YTSLHGYFVFGPTGCNLEG---FFAT------LGGEIAL-WSLVVL-----------------------AIERYVVVCKPMS-------NFRFGENHAIMGVAFTWVMALACAAPPLVGW-SRYIPEGMQCS--CGIDYYTPHEETN-----N--ESFVIY--MFVV-HFI-I----PL----------IVIFFCYGQLVFTVKE---------AAASATTQK-----AE-----------K--------------------E-----------V---TR-MVIIMVIAFLICWLPYAG--------------VAFYIFTHQ---G-S---D-F----GP-IFMTIPAFFA--KTSAV--YNPVIYIMMNKQFRNCMVTTLCCGKNPSTTVSKTETSQVAPA------
33	HHSearch	80.06	17%	-152	- C2 -	2Z73		OPSD_TODPA	A:[33-333]	-------------------------------------------------------------VYYSLGIF---------IGICGIIGCGGNGIVIYLFTK-----T--KSLQTPANMFIIN-------------LAFSDFTFSLVNGFPLMT-----ISCFLKKWIFGFAACKVYG---FIGG------IFGFMSI-MTMAMI-----------------------SIDRYNVIGRPMAASKKMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAY----TL-EGVLCNCS--FDYIS-----RDS-----T--TRSNIL--CMFILGFF-G----PI----------LIIFFCYFNIVMSVSN---------H-------E-----KE-----------MAAMAKRLNAKELRKAQAGANA-----------E---MR-LAKISIVIVSQFLLSWSP--------------YAVVALLAQ---F-G---PLE----WV-TPYAAQLPVMFAKASAI--HNPMIYSVSHPKFREAISQTFPWVLTCCQ-------------------
38	Fugue	78.54	17%	-132	- C2 -	1U19		OPSD_BOVIN	A:[4-349]	-----------MNGTEGPNFYVPFSNKTGVVRSPFEA---------------PQYYL--AEPWQFSMLA---------AYMFLLIMLGFPINFLTLYVT-----VQHKKLRTPLNYILLN-------------LAVADLFMVFGG-FTTTL-----YTSLHGYFVFGPTGCNLEG---FFAT------LGGEIAL-WSLVVL-----------------------AIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEG--------MQCS--CGIDYYTPHEETN-----N--ESFVIY--MFVVH-FI-I----PL----------IVIFFCYGQLVFTVKE---------A-------A-----AQ-----------Q--------------------QESATTQKAEKEV---TR-MVIIMVIAFLICWLPYAG--------------VAFYIFTHQ---G-S---D-F----GP-IFMTIPAFFA--KTSAV--YNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA
31	HHSearch	74.34	14%	-148	- C2 -	2KS9		NK1R_HUMAN	A:[34-324]	----------------------------------------------------------------LWAAA---------YTVIVVTSVVGNVVVMWIILA-----H--KRMRTVTNYFLVN-------------LAFAEASMAAFN-TVVNF-----TYAVHNEWYYGLFYCKFHN---FFPI------AAVFASI-YSMTAV-----------------------AFDRYMAIIHPLQPRL--SATATKVVICVIWVLALLLAFPQGYY-STT----E-TMPSRVVCM--IEWPEHP---NKI-----Y--EKVYHI--CVTVLIYF-L----PL----------LVIGYAYTVVGITLWA---------S-------E-----IPGDSSDRYHEQVS--------------------A-----------K---RK-VVKMMIVVVCTFAICWLP--------------FHIFFLLPY---I-N---P-DLYL-KKFIQQVYLAIMWLAMSSTM--YNPIIYCCLNDRFRLGFKHAFRCCPFISA-------------------
27	HHSearch	71.05	15%	-145	* C2 *	1U19		OPSD_BOVIN	A:[41-328]	---------------------------------------------------------------SMLAAY---------MFLLIMLGFPINFLTLYVTVQ-----H--KKLRTPLNYILLN-------------LAVADLFMVFGG-FTTTL-----YTSLHGYFVFGPTGCNLEG---FFAT------LGGEIAL-WSLVVL-----------------------AIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGWSRY----IP-EGMQCSCG--IDYYTP---HEET-----N--NESFVI--YMFVVHFI-I----PL----------IVIFFCYGQLVFTVKE---------A-------A-----AQ-----------QQESATTQK------------A-----------E---KE-VTRMVIIMVIAFLICWLP--------------YAGVAFYIF---THQ---G-S----DF-GPIFMTIPAFFAKTSAV--YNPVIYIMMNKQFRNCMVTTLCCGKNPLG-------------------
30	HHSearch	67.93	14%	-138	- C2 -	2LNL	-	CXCR1_HUMAN	A:[38-323]	-------------------------------------------------------------NKYVVIIA---------YALVFLLSLLGNSLVMLVILY-----S--RVGRSVTDVYLLN-------------LALADLLFAL-T-LPIWA-----ASKV-NGWIFGTFLCKVVS---LLKE------VNFYSGI-LLLACI-----------------------SVDRYLAIVHATRTLT-QKRHLVKFVCLGCWGLSMNLSLPFFLF-RQ-AY--HP-NNSSPVCY--EVLGN---DT-AK-----W--RMVLRI--LPHTFGFI-V----PL----------FVMLFCYGFTLRTLFK---------A-------H------M-----------G--------------------Q-----------K---HR-AMRVIFAVVLIFLLCWLP--------------YNLVLLADTLMRT-QVIQE-SCERRNN-IGRALDATEILGFLHSC--LNPIIYAFIGQNFRHGFLKILAMHG-----------------------
18	PsiBlast_PDB	67.55	23%	-158	- C2 -	3RZE		ENLYS_BPT4 (first)	A:[11-198]	-----------------------------------------------------------------LVVV---------LSTICLVTVGLNLLVLYAVRS-----E--RKLHTVGNLYIVS-------------LSVADLIVGAVV-MPMNI-----LYLLMSKWSLGRPLCLFWL----SMD------YVASTASIFSVFIL-----------------------CIDRYRSVQQPLRY---------LKYRTKTRASATILGAWFLSFLWVIPIL-GWN---H----------RREDKCETD-----F--YDVTWFKVMTAIINFY-L----PT----------LLMLWFYAKIYKAVRQ---------H-------C-----NI-----------F--------------------E-----------M---LR-IDEGLRLKIYKDTEGYYT--------------IGIGHLLTK---S-P---S-L----NA-AKSELDKAIG--RNTNG--VITKDEAEKLFNQDVDAAVRGILRNAKLK-------------------
26	HHSearch	66.35	21%	-179	- C2 -	3EML		ENLYS_BPT4	A:[22-222]	---------------------------------------------------------------SVYITV---------ELAIAVLAILGNVLVCWAVWL-----N--SNLQNVTNYFVVS-------------LAAADIAVGVLA-IPFAI-----TIST--GFCAACHGCLFIA---CFVL------VLTQSSI-FSLLAI-----------------------AIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQ--------SQGCG--EGQ---VACLFED-----VVPMNYMVY--FNFFACVL-V----PL----------LLMLGVYLRIFLAARR---------Q-------L-----NI-----------F--------------------E-----------M---LR-IDEGLRLKIYKDTEGYYT--------------IGIGHLLTK---S-P---S-L----NA-AKSELDKAIG--RNTNG--VITKDEAEKLFNQDVDAAVRGILRNAKLK-------------------
43	Fugue	66.34	18%	-167	- C1 -	4L9P		?	B:[68-519]	VHPGIPALFREPPLIHDLLSTETTELQSETVNKCLPLLKGIHNSQKGPFNKYGIPAL--QRKDHLEYLYDSLEDYPASFVALDASRPWMVYWALAGLCLLGEDVT--RFRERVISTFTAAQNSTGGIGGGHGQMSHVASSYAAVL-SIAMVGGEEAFKLIDRKAMWKWLGKLKQPDGGFTVCEGGEEDVRGAYCA-MVVHALLDLPLALPPEAEARQNGLETFTDGLPEYLSRCQTYEGGISGSPGS--EAHGAYAFCALACLCLLGRPEVVVPRYMNIATLLPWLSARQYAPEGGFSGRTNKLVDGCY--SHWVGN--CWPLVQAA-LDGTQPLAGPKRSSVGNLYSREGLTRYILSCCQ---------C-------KLGGLRDK-----------P--------------------G-----------K---HPDSYHTCYALTGLSTVQYYHYCTDSSVSSKDDFSSAFSWKHDP---N-F---A-S----DG-QGSDIGV-FT--ENDRLVPFHP-IFVIPHKSAEDIRVWFENQSFDL---------------------