@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : O2AG2_HUMAN: (2016-01-11 )
MELRNSTLGSGFILVGILNDSGSPELLYATFTILYMLALTSNGLLLLAITIEARLHMPMYLLLGQLSLMDLLFTSVVTPKALADFLRRENTISFGGCALQMFLALTMGSAEDLLLAFMAYDRYVAICHPLKYMTLMSPRVCWIMVATSWILASLIAIGHTMYTMHLPFCVSWEIRHLLCEIPPLLKLACADTSRYELIIYVTGVTFLLLPISAIVASYTLVLFTVLRMPSNEGRKKALVTCSSHLIVVGMFYGAATFMYVLPSSFHSPKQDNIISVFYTIVTPALNPLIYSLRNKEVMRALRRVLGKYILLAHSTL
Atome Classification :
(20 SA)
------------.........10.....----------------.-..20........30........40........50........60........70......-..80........90........100-....-----.....110.......120.......130.......140..-.....150.......160----------.........170.......180.......--------190------.........200.......210.......220...--------..---------..230----.-----------.--------------------..----.....240.......250------.-------........260..-..---.-----..270--........280.......290.......300...---------....310....----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MELRNSTLGS
G
F
I
L
V
G
----------------
I
-LNDSGSP
E
L
L
Y
A
T
F
T
I
L
Y
M
L
A
LTSN
G
L
L
L
L
A
I
T
I
E
A
R
LHM
P
M
Y
L
L
L
G
Q
L
S
L
M
D
L
L
F
T
SVV-
T
P
K
A
L
A
D
F
L
RRENTIS
F
G
G
C
A
L
Q
---
M
F
L
A
-----
L
TMG
S
A
E
D
L
L
L
A
F
M
A
YD
R
Y
V
A
I
CH
P
L
K
Y
M
TLMSP
R
V
C
W
I
M
-
V
A
T
S
W
I
L
A
S
L
I
A
IG
H
T
------------
M
Y
T
M
HL
P
F
CV
S
W
E
I
R
H
L
L
CEIPPL
L
K
L
AC--------A--------DTS
R
Y
E
L
I
I
Y
VT
G
V
T
F
L
L
L
P
I
S
A
I
V
A
S
Y
T
L
V
L
F
T
V
--------
L
R---------MPS------N-----------E--------------------GR----
K
K
A
L
V
TCSS
H
L
I
V
V
G
M
--------
F
-------YG
A
A
T
F
M
Y
VLPSS-FH---S-----PKQD---N
I
I
S
V
F
Y
T
I
V
T
P
A
L
N
P
L
I
Y
S
LR
N
K
E
V
M
R
A
L
R
R
V
L
---------
G
K
Y
I
L
L
AHSTL----------
52
Fugue
86.58
23%
-111
- C3 -
1U19
15
OPSD_BOVIN
A:
[4-349]
MN
G
T
E
G
PNFYVP
F
S
N
K
T
G
V
V
R
S
P
F
E
A
P
Q
----------------
Y
Y
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
-
R
Y
----
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
--------
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
-
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
QQQESA
T
-----------
T
--------------------
Q
K
----
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
--------
L
-------
I
C
W
L
P
Y
A
G
V
A
F
Y
I
-
F
T
---
H
QGSDF
G
P
I
F
---
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
CGKNPLGD
D
E
A
S
T
T
V
S
K
T
E
TSQVAPA---
51
Fugue
85.54
23%
-115
- C3 -
1F88
8
OPSD_BOVIN
A:
[1-348]
---------------
M
N
G
T
E
G
P
N
F
Y
V
P
F
SNKTGVVRSPFEAPQY
Y
-
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
R
-----
Y
I
P
E
G
M
Q
C
S
C
--------
G
I
DYYTPH-
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
KEAAASAT
T
Q
---------
K
A
E
------
K
-----------
E
--------------------
V
T
----
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
--------
Y
-------
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
D
F
---
G
-----
P
I
F
M
---
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
P
S
T
T
V
S
KTETS
Q
V
A
P
A
38
HHSearch
84.49
17%
-131
- C3 -
2KS9
1
NK1R_HUMAN
A:
[35-324]
-------------------------------------------------------
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
---
N
F
F
P
-----
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
-
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
------------
Y
Y
S
T
T
----
E
-
T
M
P
S
R
V
V
C
M
I
E
W
P
E
H
P
N
-------------------
K
I
Y
E
K
V
Y
H
I
C
V
T
V
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
I
T
L
--------
W
A
---------
S
E
I
------
P
GDSSDRYH
E
Q
V
S
--------------------
A
K
----
R
K
V
V
K
M
M
I
V
V
V
C
T
F
A
I
--------
C
-------
W
L
P
F
H
I
F
F
L
L
P
Y
I
-
N
P
---
D
LYL--
K
K
F
I
Q
Q
V
Y
L
A
I
M
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
---------
R
C
C
P
F
I
S
A
G
D
Y
----------
44
HHSearch
84.48
18%
-133
- C3 -
2Z73
5
OPSD_TODPA
A:
[34-332]
----------------------------------------------------
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
---
G
F
I
G
-----
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
-
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
------------
F
G
W
G
A
----
Y
T
L
E
G
V
L
C
N
C
S
F
D
Y
I
S
R
---------------------
D
S
T
T
R
S
N
I
L
C
M
F
I
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
M
S
V
--------
S
N
---------
H
E
K
------
E
-----------
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
----
M
R
L
A
K
I
S
I
V
I
V
S
Q
F
L
L
--------
S
-------
W
S
P
Y
A
V
V
A
L
L
A
Q
F
-
G
P
LEW
V
-----
T
P
Y
A
---
A
Q
L
P
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
---------
P
W
V
L
T
C
C
Q
F
D
D
----------
10
PsiBlast_PDB
83.79
21%
-147
- C3 -
3VG9
8
?
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
CFV
L
V
L
T
Q
S
S
I
F
S
L
L
A
--
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQ-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L
K
Q
M
E
S
Q
P
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
R
---------------
11
PsiBlast_PDB
83.59
21%
-147
- C3 -
3VGA
1
AA2AR_HUMAN
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
S
I
F
S
L
L
A
--
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQ-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L
K
Q
M
E
S
Q
P
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
----------------
14
PsiBlast_PDB
83.36
21%
-147
- C3 -
4UG2
3
?
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--------
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQPK
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L-------------------------------------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
R
---------------
12
PsiBlast_PDB
83.11
21%
-142
- C3 -
2YDO
3
?
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--------
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQPK
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L
K
Q
M
E
S----------------------------------------------T
L
--
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
R
Q
Q
E
P
F
----------
4
PsiBlast_PDB
83.02
21%
-148
- C3 -
3PWH
1
?
A:
[18-305]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQP--------
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
-------------------
6
PsiBlast_PDB
82.63
21%
-147
- C3 -
3RFM
1
AA2AR_HUMAN
A:
[18-305]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQP--------
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
-------------------
5
PsiBlast_PDB
82.46
21%
-150
- C3 -
3REY
1
AA2AR_HUMAN
A:
[18-305]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQP--------
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
-------------------
13
PsiBlast_PDB
82.10
21%
-143
- C3 -
2YDV
6
?
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--------
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQPK
E
G
K
A
H
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L
K
Q
M
ESQ---------------------------------------------S
T
L
-
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
R
Q
Q
E
P
F
----------
7
PsiBlast_PDB
81.99
21%
-149
- C3 -
3UZA
1
AA2AR_HUMAN
A:
[18-305]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQP--------
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
-------------------
8
PsiBlast_PDB
81.56
21%
-148
- C3 -
3UZC
1
AA2AR_HUMAN
A:
[18-305]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQP--------
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
-
S
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
A
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
-------------------
15
PsiBlast_PDB
81.24
21%
-140
- C3 -
4UHR
1
AA2AR_HUMAN
A:
[18-308]
----------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--------
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
--
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
-
I
A
I
C
W
V
L
S
--
F
A
I
G
L
T
PMLGWNNCGQPK
E
G
K
A
---
G
C
G
E
G
Q
V
A
C
L
F
E
D
V
V
P
M
---------------------------
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
--------
R
R
Q
L
K
Q
M
E
S
QP
L
P
G
------
E
-----------
R
--------------------
A
R
S
T
L
-
Q
K
E
V
H
A
A
K
S
L
A
I
I
V
G
L
--------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
C
--
H
---
A
-----
P
L
W
L
---
M
Y
L
A
I
V
L
S
H
T
N
S
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
---------
R
S
H
V
L
R
Q
Q
E
P
F
----------
16
PsiBlast_PDB
80.15
23%
-128
- C3 -
3C9M
1
OPSD_BOVIN
A:
[39-312]
------------------------------------------------------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
--
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
-
R
Y
----
I
P
E
G
M
Q
C
S
C
--------
G
IDYYTPHE
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
-
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
------
Q
-----------
Q
--------------------
Q
E
SATT
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
C
F
---
G
-----
P
I
F
M
---
T
-
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
P
---------------
18
PsiBlast_PDB
77.94
23%
-115
- C3 -
4BEZ
3
OPSD_BOVIN
A:
[42-313]
------------------------------------------------------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
D
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
--
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
-
R
Y
----
I
P
E
G
M
Q
C
S
C
--------
G
IDYYTPHE
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
-
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
------
Q
-----------
Q
--------------------
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
C
F
---
G
-----
P
I
F
M
---
T
-
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
----------------
41
HHSearch
77.17
20%
-121
- C3 -
1U19
14
OPSD_BOVIN
A:
[41-328]
-----------------------------------------------------
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
------------
V
G
W
S
R
---
Y
I
-
P
E
G
M
Q
C
S
C
G
I
D
Y
Y
T
P
H
-------------------
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
------
Q
-----------
Q
QESA
T
T
Q
K
------------
A
E
----
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
--------
C
-------
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
SD-
F
-----
G
P
I
F
---
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
P
L
G
D
D
E
----------
19
PsiBlast_PDB
76.14
23%
-114
- C3 -
4BEY
4
OPSD_BOVIN
A:
[42-313]
------------------------------------------------------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
D
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
--
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
-
R
Y
----
I
P
E
G
M
Q
C
S
C
--------
G
IDYYTPHE
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
-
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
------
Q
-----------
Q
--------------------
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
C
F
---
G
-----
P
I
F
M
---
T
-
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
----------------
9
PsiBlast_PDB
75.59
23%
-112
- C3 -
2X72
5
GNAT1_BOVIN (first)
A:
[42-313]
------------------------------------------------------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
Q
---
G
F
F
A
-----
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
--
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------------
A
P
P
L
V
G
W
S
-
R
Y
----
I
P
E
G
M
Q
C
S
C
--------
G
IDYYTPHE
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
-
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--------
K
E
---------
A
A
A
------
Q
-----------
Q
--------------------
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
T
H
Q
G
S
-
C
F
---
G
-----
P
I
-
F
---
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
---------
C
C
G
K
N
----------------