@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2C3_HUMAN: (2016-01-13 )
MMEIANVSSPEVFVLLGFSTRPSLETVLFIVVLSFYMVSILGNGIIILVSHTDVHLHTPMYFFLANLPFLDMSFTTSIVPQLLANLWGPQKTISYGGCVVQFYISHWLGATECVLLATMSYDRYAAICRPLHYTVIMHPQLCLGLALASWLGGLTTSMVGSTLTMLLPLCGNNCIDHFFCEMPLIMQLACVDTSLNEMEMYLASFVFVVLPLGLILVSYGHIARAVLKIRSAEGRRKAFNTCSSHVAVVSLFYGSIIFMYLQPAKSTSHEQGKFIALFYTVVTPALNPLIYTLRNTEVKSALRHMVLENCCGSAGKLAQI
Atome Classification :
(20 SA)
-------------.........10........20--------------.........30........40........50........60........70.-----......-.80....-....90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190-------...----.....200....---..--.---210.......220---.....---...230..-----------------.....240-----------.......250-----......---...260...---.-----.-----..270...-------.------.....280.......290.......300.....---------..310-........320------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------MMEIANVSSP
E
V
F
V
L
LGFST---------------RP
S
L
E
T
V
L
F
I
V
V
L
S
F
Y
M
V
S
I
LGN
G
I
I
I
L
V
S
HT
D
V
H
LHT
P
M
Y
F
F
L
ANLPFLD
M
-----
S
F
T
T
S
I
-
V
P
Q
L
L
A
N
-LWGPQKTISYG
G
C
V
V
Q
F
Y
I
S
H
WL
G
A
T
E
C
V
L
L
A
TMSY
D
R
Y
A
A
I
CR
P
L
H
Y
T
V
I
M
H
P
Q
L
C
L
G
L
A
L
A
S
W
L
G
G
L
T
T
S
M
V
G
S
T
L
T
M
L
L
P
L
CGN
N
C
I
D
H
F
F
CE
M
P
L
I
M
Q
L
A
C-V-------DT
S
----
L
N
E
M
E
M
Y
L
A
S
F
V
---
F
V
--
V
---
L
P
L
G
L
I
L
V
S
Y
G
H
----
I
A
R
A
V
---
L
K
I
RSAEG-----------------
R
R
K
A
F
N
T
C
-----------
S
S
H
V
A
V
V
S
-------
L
F
Y
G
S
I
---
I
F
M
Y
LQPAK---S-----T-----SHE--Q
G
K
-------
F
------
I
A
L
F
Y
T
V
V
T
P
A
L
N
P
L
I
Y
T
LR
N
T
E
V
K
S
A
L
R
H
M
V
L
---------
E
N
CC--GSAGKLAQI--------------------------
32
HHSearch
85.55
18%
-133
- C5 -
2Z73
5
OPSD_TODPA
A:
[32-334]
--------------------------------------------------
A
V
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
-----
T
F
S
L
V
N
G
F
P
L
M
T
I
S
-
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
T
L
----
E
G
V
L
C
N
C
S
F
D
Y
I
S
-------------
R
D
S
----
T
T
R
S
N
I
L
C
M
F
I
L
---
G
F
--
F
---
G
P
I
L
I
I
F
F
C
Y
F
N
----
I
V
M
S
V
---
S
N
H
E
K
E
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
M
R
L
A
-----------
K
I
S
I
V
I
V
S
-------
Q
F
L
L
S
W
S
P
Y
A
V
V
A
L
L
A
Q
F
---
G
-----
P
LEW--
V
T
P
--
Y
A
A
-------
Q
------
L
P
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
P
---------
W
V
L
T
--
C
C
Q
F
D
D
K
E
T
--------------------------
39
Fugue
85.16
19%
-113
- C5 -
1U19
15
OPSD_BOVIN
A:
[4-349]
----------------
M
N
G
T
E
G
P
N
F
Y
V
P
F
S
N
K
T
GVVRSPFEAPQYYLA
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
-
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
--------
A
P
P
L
V
G
---
W
S
R
Y
I
P
E
G
---
M
Q
C
S
C
-
G
I
DYYTPH
E
E
T
----
N
N
E
S
F
V
I
Y
M
F
V
V
---
H
F
--
I
---
I
P
L
I
V
I
F
F
C
Y
G
Q
----
L
V
F
T
V
---
K
E
A
A
A
Q
Q
Q
ESA
T
-------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
-------
I
A
F
L
I
C
---
W
L
P
Y
A
G
V
A
F
---
Y
-----
I
-----
F
T
H
--
Q
G
S
DFGPIFM
T
------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
CGKNPLGDD
E
A
S
T
--
T
V
S
K
T
E
T
S
Q
VAPA----------------------
38
Fugue
84.59
18%
-118
- C5 -
1F88
8
OPSD_BOVIN
A:
[1-348]
MN
G
T
E
G
PNFYVPF
S
N
K
T
G
V
V
R
S
P
F
E
A
P
Q
Y
Y
L
A
E
----------------
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
-
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
--------
P
P
L
V
G
------
W
S
R
Y
I
P
E
G
M
Q
C
S
C
-
G
I
DYYTPH
E
E
T
----
N
N
E
S
F
V
I
Y
M
F
V
V
---
H
F
--
I
---
I
P
L
I
V
I
F
F
C
Y
G
Q
----
L
V
F
T
V
---
K
E
A
A
A
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
-------
I
A
F
L
I
C
---
W
L
P
Y
A
G
V
A
F
---
Y
-----
I
-----
F
T
H
--
Q
G
S
DFGPIFM
T
------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
---------
C
G
K
N
--
P
S
T
T
V
S
K
T
E
TS
Q
V
A
P
A-------------------
7
PsiBlast_PDB
82.37
22%
-124
- C5 -
3DQB
6
GNAT1_BOVIN (first)
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
6
PsiBlast_PDB
81.93
22%
-115
- C5 -
1F88
7
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VFT
V
K
E
A
A
---
A
----
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
P
S
T
T
V
S
--------------------------
43
Fugue
81.89
17%
-117
- C5 -
4XNV
15
P2RY1_HUMAN (first)
A:
[38-382]
--------------------
S
F
K
C
A
L
T
K
T
G
F
--------------------
Q
F
Y
Y
L
P
A
V
Y
I
L
V
F
I
I
G
F
L
G
N
S
V
A
I
W
M
F
V
F
H
M
K
P
W
S
G
I
S
V
Y
M
F
N
L
A
L
A
D
F
-----
L
Y
V
L
T
L
-
P
A
L
I
F
Y
Y
-
F
N
K
T
D
W
I
F
G
D
A
M
C
K
L
Q
R
F
I
F
H
V
N
L
Y
G
S
I
L
F
L
T
C
I
S
A
H
R
Y
S
G
V
V
Y
P
-
K
S
L
G
R
L
K
K
K
N
A
I
C
I
S
V
L
V
W
L
------
I
V
V
V
A
I
S
P
I
L
F
Y
S
G
T
G
V
R
K
N
--------
K
T
I
T
C
-
Y
-------
D
T
T
SDEY
L
R
S
Y
F
I
Y
S
M
C
T
T
---
V
A
MF
C
---
V
P
L
V
L
I
L
G
C
Y
G
L
----
I
V
R
A
L
I
Y
K
M
K
K
Y
T
C
T
V
-----------------
C
G
Y
I
Y
N
P
E
DGDPDNGVNPG
T
D
F
K
D
I
V
C
-------
P
L
C
G
V
G
---
K
D
Q
F
E
E
V
E
E
---
P
-----
L
-----
R
R
K
--
S
I
Y
-------
L
------
V
I
I
V
L
T
V
F
A
V
S
Y
I
P
F
-
H
V
M
K
T
M
N
L
R
A
R
L
D
F
Q
T
P
---------
A
M
C
A
F
N
D
R
V
Y
A
T
Y
Q
V
T
R
G
L
A
S
L
N
S
C
V
N
P
I
L
Y
F
LAGDTFRRR
10
PsiBlast_PDB
81.72
22%
-120
- C5 -
4J4Q
9
GNAT1_BOVIN (first)
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
16
PsiBlast_PDB
81.37
22%
-118
- C5 -
2I35
3
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPI
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
D
D
E
-----------------------------
8
PsiBlast_PDB
81.25
22%
-123
- C5 -
3PQR
9
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
30
HHSearch
80.96
18%
-105
- C5 -
2LNL
-
CXCR1_HUMAN
A:
[37-322]
--------------------------------------------------
L
N
K
Y
V
V
I
I
A
Y
A
L
V
F
L
L
S
L
L
G
N
S
L
V
M
L
V
I
L
Y
S
R
V
G
R
S
V
T
D
V
Y
L
L
N
L
A
L
A
D
L
-----
L
F
A
L
T
--
L
P
I
W
A
A
S
-
K
V
-
N
G
W
I
F
G
T
F
L
C
K
V
V
S
L
L
K
E
V
N
F
Y
S
G
I
L
L
L
A
C
I
S
V
D
R
Y
L
A
I
V
H
A
T
R
T
L
T
-
Q
K
R
H
L
V
K
F
V
C
L
G
C
W
G
L
S
M
N
L
S
L
P
F
F
L
F
R
Q
A
Y
---
H
-
P
N
N
S
S
P
V
C
Y
E
V
L
G
N
D
------------
T
A
K
----
W
R
M
V
L
R
I
L
P
H
T
F
---
G
F
--
I
---
V
P
L
F
V
M
L
F
C
Y
G
F
----
T
L
R
T
L
---
F
K
A
H
M
G
-
Q
-----------------
K
H
R
A
M
R
V
I
-----------
F
A
V
V
L
I
F
L
-------
L
C
W
L
P
Y
---
N
L
V
L
L
A
D
T
L
M
RT
Q
VIQE
S
C
E
R
---
R
N
N
I
G
R
A
L
-------
D
------
A
T
E
I
L
G
F
L
H
S
C
L
N
P
I
I
Y
A
F
I
G
Q
N
F
R
H
G
F
L
K
I
L
A
---------
M
H
G
--------------------------------------
11
PsiBlast_PDB
80.88
22%
-120
- C5 -
4PXF
7
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
9
PsiBlast_PDB
80.77
22%
-121
- C5 -
3PXO
5
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
4
PsiBlast_PDB
80.55
22%
-120
- C5 -
3CAP
5
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
19
PsiBlast_PDB
80.34
22%
-115
- C5 -
2PED
13
OPSD_BOVIN
A:
[58-326]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
FT
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
P
L
G
D
D
E
--------------------------
3
PsiBlast_PDB
80.26
22%
-112
- C5 -
4A4M
5
OPSD_BOVIN
A:
[58-326]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
----
L
V
F
T
V
---
K
E
A
A
A
Q
Q
Q
-----------------
E
S
A
T
T
Q
K
A
-----------
E
K
E
V
T
R
M
V
-------
I
I
Y
V
I
A
---
F
L
I
C
W
L
P
Y
A
---
G
-----
V
A
F
Y
I
F
T
H
Q
--
G
S
C
-------
F
G
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
20
PsiBlast_PDB
80.11
22%
-116
- C5 -
2G87
13
OPSD_BOVIN
A:
[58-326]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VFT
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
P
L
G
D
D
E
--------------------------
5
PsiBlast_PDB
80.07
22%
-115
- C5 -
3C9L
13
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
D
D
E
-----------------------------
12
PsiBlast_PDB
79.87
22%
-116
- C5 -
3OAX
16
OPSD_BOVIN
A:
[58-326]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
FT
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPI
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
P
L
G
D
D
E
--------------------------
15
PsiBlast_PDB
79.84
22%
-126
- C5 -
2I36
2
OPSD_BOVIN
A:
[55-325]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
ICW
L
P
Y
A
G
V
---
A
F
Y
I
F
-------------------
T
H
Q
--
G
S
D
-------
F
GPIFMT
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------
2
PsiBlast_PDB
79.51
23%
-105
- C5 -
2X72
7
GNAT1_BOVIN (first)
A:
[58-326]
----------------------------------------------------------------------
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
------
G
C
N
L
Q
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
-
T
W
V
M
A
L
A
C
A
A
P
--------
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
G
I
-------
D
Y
Y
----
T
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
---
A
Q
Q
Q
E
S
A
T
-----------------
T
Q
K
A
E
K
E
V
-----------
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
---
A
F
Y
I
F
T
H
Q
G
---
S
-----
C
-----
F
G
P
--
I
F
M
-------
T
------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
---
M
V
T
---------
T
L
C
C
--
G
K
N
--------------------------------