@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2I1_HUMAN: (2016-01-13 )
MLANQASAEERFLLLGFSDWPSLQPVLFALVLLCYLLTLTGNSALVLLAVRDPRLHTPMYYFLCHLALVDAGFTTSVVPPLLANLRGPALWLPRSHCTAQLCASLALGSAECVLLAVMALDRAAAVCRPLRYAGLVSPRLCRTLASASWLSGLTNSVAQTALLAERPLCAPRLLDHFICELPALLKLACGGDGDTTENQMFAARVVILLLPFAVILASYGAVARAVCCMRFSGGRRRAVGTCGSHLTAVCLFYGSAIYTYLQPAQRYNQARGKFVSLFYTVVTPALNPLIYTLRNKKVKGAARRLLRSLGRGQAGQ
Atome Classification :
(20 SA)
.........10........20--------------.....----------------....30........40........50........60........70----.......-..80........90........100.......110.......120.......130.......140.......150.......160......-.170.......180.......190----.......200..--...--.--.210.......220--.........----230--------------------.......240.......250-------........260...------.------.---..270.-------......280.......290.......300....-----------...310....------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLANQASAE
E
R
F
L
L
L
GFSDW---------------PS
L
Q
P
----------------
V
L
F
A
L
V
L
L
C
Y
L
L
T
LTGN
S
A
L
V
L
L
A
VRDPRLH
T
P
M
Y
Y
F
L
C
H
L
A
L
VD-----AGFTTS
V
-
V
P
P
L
L
A
NLRG
P
A
L
W
LPRSH
C
T
A
Q
L
C
A
S
L
ALG
S
A
E
C
V
L
L
A
V
M
A
L
D
R
A
A
A
V
C
R
P
L
R
Y
AGLV
S
P
R
L
C
R
T
L
A
S
A
S
W
L
S
G
L
T
N
S
V
A
Q
T
A
L
LAERPL-
C
A
P
R
L
L
D
H
F
I
C
E
L
P
A
L
L
K
L
ACGGD----GDTTE
N
Q
M
F
A
A
R
--
V
V
I
--
L
--
L
L
P
F
A
V
I
L
A
S
Y
G
----
A
V
A
R
A
V
C
C
M----RFS--------------------GGRRRAVGT
C
G
S
H
L
T
A
V
C
L
--------
F
Y
G
S
A
I
Y
T
Y
L
Q
P
A
Q
------
R
------
Y
---
N
Q
AR
G
K
-------
F
V
S
L
F
Y
T
V
V
T
P
A
L
N
P
L
I
Y
T
L
RNK
K
V
K
G
A
A
R
R
L
L
-----------
R
S
LGRGQAGQ------------------
40
Fugue
87.01
18%
-116
- C3 -
1F88
8
OPSD_BOVIN
A:
[1-348]
---
M
N
G
T
E
G
P
N
F
Y
V
P
F
S
N
K
T
---------------
G
V
V
R
S
PFEAPQYYLAE
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
-----
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
-
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
--
M
F
V
VH
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
----
Q
L
V
F
T
V
K
E
A
----
A
A
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
--------
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
------
Y
------
I
---
F
T
H
Q
G
S
DFGPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
CGKNPSTTVS
K
T
E
T
S
Q
V
A
P
A
------------------
33
HHSearch
82.86
15%
-116
- C3 -
2Z73
5
OPSD_TODPA
A:
[33-333]
-------------------------------------
V
Y
Y
----------------
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
-----
F
T
F
S
L
V
N
G
F
P
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
----
T
-
L
E
G
V
L
C
N
C
S
F
D
Y
I
S
-----
R
D
----
S
T
-
T
R
S
N
I
L
C
M
F
--
I
L
G
--
F
--
F
G
P
I
L
I
I
F
F
C
Y
F
----
N
I
V
M
S
V
S
N
H
----
E
K
E
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
M
R
L
A
K
I
S
I
V
I
V
S
Q
F
L
L
--------
S
W
S
P
Y
A
V
V
A
L
L
A
Q
F
------
G
PLE---
W
---
V
T
P
Y
A
A
-------
Q
L
P
V
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
-----------
P
W
V
L
T
C
C
Q
F
D
------------------
3
PsiBlast_PDB
82.58
21%
-114
- C3 -
3C9L
13
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
D
D
E
--------------------
14
PsiBlast_PDB
82.37
21%
-117
- C3 -
2I35
4
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
D
D
E
--------------------
27
HHSearch
82.12
16%
-118
* C3 *
2KS9
1
NK1R_HUMAN
A:
[34-326]
--------------------------------------------------------
L
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
-----
A
S
M
A
A
F
N
-
T
V
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
N
F
F
P
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
-
S
T
T
----
E
T
-
M
P
S
R
V
V
C
M
I
E
W
P
E
H
P
---
N
K
----
I
Y
-
E
K
V
Y
H
I
C
V
T
--
V
L
I
--
Y
--
F
L
P
L
L
V
I
G
Y
A
Y
T
----
V
V
G
I
T
L
W
A
S
----
E
I
P
GDSSDRYH
E
Q
V
---------
S
A
K
R
K
V
V
K
M
M
I
V
V
V
C
T
F
A
I
--------
C
W
L
P
F
H
I
F
F
L
L
P
Y
I
NPD---
L
------
Y
LKK
F
I
Q
Q
V
Y
-------
L
A
I
M
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
-----------
R
C
C
P
F
I
S
A
G
D
------------------
5
PsiBlast_PDB
80.82
21%
-114
- C3 -
3DQB
4
GNAT1_BOVIN (first)
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
13
PsiBlast_PDB
80.67
21%
-113
- C3 -
2I36
1
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
ICWLP
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
7
PsiBlast_PDB
80.61
21%
-114
- C3 -
3PXO
4
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
8
PsiBlast_PDB
79.79
21%
-113
- C3 -
4J4Q
8
GNAT1_BOVIN (first)
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
4
PsiBlast_PDB
79.76
21%
-110
- C3 -
1F88
7
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VF
T
V
K
E
A
A
A
--------
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
P
S
T
T
V
------------------
39
Fugue
79.75
19%
-87
- C3 -
1U19
15
OPSD_BOVIN
A:
[4-349]
--
M
N
G
T
E
G
P
N
F
Y
V
P
F
S
N
K
T
G
VVRSPFEAPQYYLAE
P
W
Q
F
S
----------------
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
-----
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
---------
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
-
V
G
---
W
S
R
Y
I
P
E
G
---
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
--
M
F
V
--
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
----
Q
L
V
F
T
V
K
E
A
AAQQ
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
--------
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
------
Y
------
I
---
F
T
H
Q
G
S
DFGPIFM
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
-
C
G
K
N
P
L
G
D
DEA
S
T
T
V
S
K
TETSQVAPA
2
PsiBlast_PDB
79.52
21%
-113
- C3 -
3CAP
4
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
9
PsiBlast_PDB
79.37
21%
-114
- C3 -
4PXF
7
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
6
PsiBlast_PDB
78.82
21%
-117
- C3 -
3PQR
9
OPSD_BOVIN
A:
[42-315]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
-----------------------
10
PsiBlast_PDB
78.75
21%
-92
- C3 -
3OAX
16
OPSD_BOVIN
A:
[45-316]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
P
L
G
D
D
------------------
29
HHSearch
78.49
18%
-105
- C3 -
2LNL
-
CXCR1_HUMAN
A:
[38-323]
-------------------------------------
N
K
Y
----------------
V
V
I
I
A
Y
A
L
V
F
L
L
S
L
L
G
N
S
L
V
M
L
V
I
L
Y
S
R
V
G
R
S
V
T
D
V
Y
L
L
N
L
A
L
A
D
-----
L
L
F
A
L
-
T
-
L
P
I
W
A
A
S
K
V
-
N
G
W
I
F
G
T
F
L
C
K
V
V
S
L
L
K
E
V
N
F
Y
S
G
I
L
L
L
A
C
I
S
V
D
R
Y
L
A
I
V
H
A
T
R
T
L
T
-
Q
K
R
H
L
V
K
F
V
C
L
G
C
W
G
L
S
M
N
L
S
L
P
F
F
L
F
R
Q
A
--
Y
--
H
-
P
N
N
S
S
P
V
C
Y
E
V
L
G
N
D
----
T
A
----
K
W
-
R
M
V
L
R
I
L
P
H
--
T
F
G
--
F
--
I
V
P
L
F
V
M
L
F
C
Y
G
----
F
T
L
R
T
L
F
K
A
----
H
M
---------------------
G
Q
K
H
R
A
M
R
V
I
F
A
V
V
L
I
F
L
L
--------
C
W
L
P
Y
N
L
V
L
L
A
D
T
L
M
RTQVI
Q
E
S
C
E
R
R
N
---
N
I
G
R
A
L
-------
D
A
T
E
I
L
G
F
L
H
S
C
L
N
P
I
I
Y
A
F
I
G
Q
N
F
R
H
G
F
L
K
I
L
-----------
A
M
H
G
------------------------
15
PsiBlast_PDB
78.47
21%
-90
- C3 -
2HPY
13
OPSD_BOVIN
A:
[45-316]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
P
L
G
D
D
------------------
11
PsiBlast_PDB
78.40
21%
-91
- C3 -
1GZM
15
OPSD_BOVIN
A:
[45-316]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
D
D
E
--------------------
16
PsiBlast_PDB
78.37
21%
-91
- C3 -
2PED
13
OPSD_BOVIN
A:
[45-316]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
P
L
G
D
D
------------------
19
PsiBlast_PDB
78.17
21%
-92
- C3 -
1U19
13
OPSD_BOVIN
A:
[45-316]
-----------------------------------------------------------
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
-----
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
-
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
----------------
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTP
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
--
F
--
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
VF
T
V
K
E
A
A
A
Q
Q
----
Q
E
S
--------------------
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
Q
G
S
------
D
------
F
---
G
P
I
F
M
T
--------
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
-----------
C
C
G
K
N
P
L
G
D
D
------------------