@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2W1_HUMAN: (2016-01-13 )
MDQSNYSSLHGFILLGFSNHPKMEMILSGVVAIFYLITLVGNTAIILASLLDSQLHTPMYFFLRNLSFLDLCFTTSIIPQMLVNLWGPDKTISYVGCIIQLYVYMWLGSVECLLLAVMSYDRFTAICKPLHYFVVMNPHLCLKMIIMIWSISLANSVVLCTLTLNLPTCGNNILDHFLCELPALVKIACVDTTTVEMSVFALGIIIVLTPLILILISYGYIAKAVLRTKSKASQRKAMNTCGSHLTVVSMFYGTIIYMYLQPGNRASKDQGKFLTLFYTVITPSLNPLIYTLRNKDMKDALKKLMRFHHKSTKIKRNCKS
Atome Classification :
(20 SA)
----------.........10---------.........20........30........40---........50...---.....60........70-----......-..80.-.......90........100.......110.......120.......130.......140.......150.......160.....-----..170.......180.......190-----.........200.......210.......220.......230---.--------.-----------------......240.....---..250------------.---........260...---..---..-270..-------....--...280.......290.......300.......310.......320----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MDQSNYSS
L
H
----------
G
F
I
L
L
GFSNH
P
K
M
E
M
I
L
S
G
V
V
A
I
F
Y
L
I
T
L
VG---
N
T
A
I
I
L
A
S
L
L
DSQ---L
H
T
P
M
Y
F
F
L
RN
L
S
F
L
D
L
-----
C
F
T
T
S
I
-
I
P
Q
M
L
-
V
N
LWGPD
K
T
I
S
Y
V
G
C
I
I
Q
L
Y
V
Y
M
W
L
G
S
V
E
C
L
L
L
A
V
MSY
D
R
F
T
A
I
C
K
P
L
H
Y
F
V
V
M
N
P
H
L
C
L
K
M
I
I
M
I
W
S
I
SLAN
S
V
V
L
C
T
L
T
LNLP-----TC
G
N
N
I
L
D
H
F
L
C
EL
P
A
L
V
K
I
A
CV-------DT
T
T
V
E
M
S
V
F
A
L
G
I
I
I
V
L
T
P
L
I
L
I
L
IS
Y
G
Y
I
A
K
A
V
L
R
TK
S
K
----
A
--------
S
-----------------
Q
R
K
A
M
N
TCGS
H
L
T
V
---
V
S
M
--------------
F
---
Y
G
T
I
I
Y
M
Y
LQPGNR---AS---KD-Q--G
K
-------
F
L
T
L
--
F
Y
T
VITPSL
N
P
L
I
Y
T
LRNK
D
M
K
D
A
L
K
K
L
M
R
F
HHKS
T
K
I
KRNCKS------------
36
HHSearch
89.44
18%
-140
- C1 -
2Z73
5
OPSD_TODPA
A:
[32-333]
-----------------------------------------
A
V
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
---
N
G
I
V
I
Y
L
F
T
K
T
K
S
---
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
-----
T
F
S
L
V
N
G
F
P
L
M
T
-
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
T
-----
L
----
E
G
V
L
C
N
C
S
F
D
Y
I
S
------------
R
D
S
T
T
R
S
N
I
L
C
M
F
I
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
M
S
V
S
N
H
E
K
E
----
M
--------
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
M
R
L
A
K
I
S
I
V
I
---
V
S
Q
--------------
F
L
L
S
W
S
P
Y
A
V
V
A
L
L
A
Q
F
G
PLE
W
V
---
T
P
-
Y
--
A
A
-------
Q
L
P
V
--
M
F
A
K
A
S
A
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
P
W
V
L
T
C
C
Q
F
D
D
K
E
T
E
------------
42
Fugue
86.22
17%
-120
- C1 -
1F88
8
OPSD_BOVIN
A:
[1-348]
----------
M
N
G
T
E
G
P
N
F
Y
VPFSNKTGVV
R
S
P
F
E
A
P
Q
Y
Y
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
G
-
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
-------------------
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
S
----
A
--------
T
-----------------
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
---
M
V
I
--------------
A
---
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
---
I
F
---
T
H
-
Q
--
G
S
DFGPIFM
T
I
P
A
--
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
S
T
T
V
S
K
T
E
T
S
Q
V
A
P
A------
4
PsiBlast_PDB
85.98
21%
-146
- C1 -
1F88
7
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
-----------------------------
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
S
T
T
V
S
K
T
E
T
------------
3
PsiBlast_PDB
84.41
21%
-140
- C1 -
3C9L
13
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
D
D
E
-------------------
14
PsiBlast_PDB
83.15
21%
-144
- C1 -
2I35
4
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
D
D
E
-------------------
5
PsiBlast_PDB
82.86
21%
-145
- C1 -
3DQB
4
GNAT1_BOVIN (first)
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
9
PsiBlast_PDB
82.36
21%
-143
- C1 -
4PXF
7
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
6
PsiBlast_PDB
82.11
21%
-144
- C1 -
3PQR
9
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
15
PsiBlast_PDB
82.04
21%
-161
- C1 -
2I37
1
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
----------------------------------------
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
---
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
-------------------
13
PsiBlast_PDB
81.60
21%
-147
- C1 -
2I36
1
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
ICWLP
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
12
PsiBlast_PDB
81.47
21%
-130
- C1 -
1HZX
14
OPSD_BOVIN
A:
[40-318]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
------------------------------
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
S
T
T
V
S
K
------------
8
PsiBlast_PDB
81.27
21%
-141
- C1 -
4J4Q
8
GNAT1_BOVIN (first)
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
7
PsiBlast_PDB
81.22
21%
-138
- C1 -
3PXO
4
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
43
Fugue
81.16
18%
-104
- C1 -
1U19
15
OPSD_BOVIN
A:
[4-349]
MN
G
T
E
G
PNFY
V
P
F
S
N
K
T
G
V
V
----------
R
S
P
F
E
A
P
Q
Y
Y
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
---
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
KK
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
G
-
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
GMQC
S
C
G
---
I
D
Y
Y
T
P
H
-----------------
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
QQES
A
--------
T
-----------------
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
---
M
V
I
--------------
A
---
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
---
I
F
---
T
H
-
Q
--
G
S
DFGPIFM
T
I
P
A
--
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
D
E
A
S
T
T
V
S
K
TETSQVAPA
2
PsiBlast_PDB
81.09
21%
-141
- C1 -
3CAP
4
OPSD_BOVIN
A:
[37-317]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I
------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------------
19
PsiBlast_PDB
80.33
21%
-133
- C1 -
1L9H
14
OPSD_BOVIN
A:
[40-318]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
------------------------------
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
S
T
T
V
S
K
------------
17
PsiBlast_PDB
80.13
21%
-126
- C1 -
2PED
13
OPSD_BOVIN
A:
[40-318]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
D
E
A
S
T
T
------------
20
PsiBlast_PDB
79.88
21%
-125
- C1 -
1U19
13
OPSD_BOVIN
A:
[40-318]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
D
E
A
S
T
T
------------
16
PsiBlast_PDB
79.76
21%
-126
- C1 -
2HPY
13
OPSD_BOVIN
A:
[40-318]
----------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
---
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
-
Y
T
S
L
H
G
Y
F
V
F
G
P
------
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
M
A
L
A
-------------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
G
I
D
YYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
--
K
E
A
A
----
A
--------
Q
-----------------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
---
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
---
A
G
V
A
F
Y
I
F
T
H
Q
G
S
----------
D
-
F
--
G
P
I------
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
D
D
E
A
S
T
T
------------
35
HHSearch
79.47
14%
-144
- C1 -
2KS9
1
NK1R_HUMAN
A:
[34-325]
---------------------------------------------
L
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
---
N
V
V
V
M
W
I
I
L
A
H
K
R
---
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
-----
S
M
A
A
F
N
-
T
V
V
N
F
-
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
N
F
F
P
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
T
T
E
T
----------
M
P
S
R
V
V
C
M
I
E
W
P
E
H
---
P
-------
N
K
I
Y
E
K
V
Y
H
I
C
V
T
V
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
I
T
L
W
A
S
E
I
P
----
G
DSSDRYH
E
Q
-----------------
V
S
A
K
R
K
V
V
K
M
M
I
V
V
V
C
T
F
A
I
--------------
C
---
W
L
P
F
H
I
F
F
L
L
P
Y
I
N
---
P
D
LYL
K
K
F
I
Q
Q
V
Y
-------
L
A
I
M
--
W
L
A
M
S
S
T
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
R
C
C
P
F
I
S
A
G
D
Y
E
G
L
E
------------