@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CSF1R_HUMAN: (2015-06-17 )
MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPSSSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC

Atome Classification :

(87 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570-.----------......580.......590.......600.....--.--.610.........620.......630.......640.......650...-....660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.....----..910.......920.......930.......940.......950.......960.......970
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQEDRRERDYTNLPSSSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC
117 HHSearch 78.8994%-113 - C6 -2I1M A:[13-332] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVRWKIIESY--NSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKSRVLET-------D-------------------------------------------------------STASTRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQEDRRER---------------------------------------------------
4 PsiBlast_PDB 77.7482%-122 - C6 -2I0Y ? A:[14-329] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRWKIIESYE--SYTFI---------E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKR------------------------------------------------------------Q---------LSSRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQE--------------------------------------------------------
3 PsiBlast_PDB 77.0882%-115 - C6 -2I0V A:[10-329] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKYQVRWKIIESYEGNSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKR------------------------------------------------------------Q---------LSSRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQE--------------------------------------------------------
5 PsiBlast_PDB 76.6481%-110 - C6 -2I1M A:[13-332] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVRWKIIESY--NSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKSRVL------------------------------------------ETD-------STAST-------------RDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQEDRRER---------------------------------------------------
2 PsiBlast_PDB 75.9687%-120 - C6 -4HW7 A:[36-338] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--D--AV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCTYGDLLNFLRRKAEAMLGPS------------------------------------------------------------GRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIT----SFLQEQA----------------------------------------------------------
121 HHSearch 72.9169%-113 - C6 -1T46 A:[1-308] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNNYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTI-GGPTLVITEYCCYGDLLNFLRRKRDSF-----------------------------------------------------------------LALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQISESTN-----------------------------------------------------
8 PsiBlast_PDB 72.5360%-106 - C6 -4HVS KIT_HUMAN A:[10-331] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMYEVQWKVVEESNGNNYSYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKS--D--AA--MTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTH-GGPTLVITEYCCYGDLLNFLRRK--------------------------------RDSFHSS-------DTSPASM------------EDDENALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEHAPAEMYDIMKTCWDADPDKRPTFKQIV----QDIEKQISES-------------------------------------------------------
18 PsiBlast_PDB 71.9247%-120 - C6 -1Y6B A:[14-363] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS---KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--A--TC--RTVAVKMLK--ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PY--------------------------------------------------------------FLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF--------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
132 HHSearch 70.8049%-110 - C6 -3VHE A:[8-356] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYK---------------------------------------------------------DLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRK--ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELV----EHLGNLLQANAQ-----------------------------------------------------
40 PsiBlast_CBE 70.2246%-124 - C6 -3B8R B:[7-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PYDAS----------KWEFPRDRLKLGKPLGR---GQVIEADAFGIDKT--A--TC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK--------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA------------------------------------------------------------
17 PsiBlast_PDB 70.2247%-123 - C6 -1Y6A A:[15-362] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----KWEFPRDRLKLGKPLGR----QVIEADAFGIDKT--A--TC--RTVAVKML----THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PY----------------------------------------------------------D---FLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF--------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN-----------------------------------------------------------
20 PsiBlast_PDB 70.1248%-112 - C6 -3VHE A:[9-359] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PYK-----------------------------------------------------DLYKD---FLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRK--ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQ---------------------------------------------------------
45 PsiBlast_CBE 70.0146%-127 - C6 -2QU6 B:[8-301] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDAS----------KWEFPRDRLKLGKPLGR----QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVP-------------------------------------------------------------F---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
66 PsiBlast_CBE 69.9444%-120 - C6 -4F64 FGFR1_HUMAN A:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPL-----GQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
41 PsiBlast_CBE 69.6946%-118 - C6 -3B8R VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
19 PsiBlast_PDB 69.6147%-107 - C6 -3VHK A:[11-365] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PYK-------------------------------------------------------YKD---FLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRK--ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
88 PsiBlast_CBE 69.5643%-111 - C6 -3C4F FGFR1_HUMAN A:[1-291] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
51 PsiBlast_CBE 69.5545%-113 - C6 -2P2I VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID-------TC--RTVAVKML----THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
106 PsiBlast_CBE 69.5443%-122 - C6 -2PVY ? D:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPL------QVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG------------------------------------------------------VPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKNTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
96 PsiBlast_CBE 69.4443%-116 - C6 -4J97 B:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPLGE---GQVVMAEAVGID-------EA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG---------------------------------------------------INRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
35 PsiBlast_CBE 69.4446%-123 - C6 -3CPB B:[6-301] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--A--TC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK---------------------------------------------------------KDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
87 PsiBlast_CBE 69.4243%-112 - C6 -3C4F B:[1-291] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
43 PsiBlast_CBE 69.4246%-114 - C6 -3B8Q VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
97 PsiBlast_CBE 69.3943%-121 - C6 -4J97 FGFR2_HUMAN A:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPLGE---GQVVMAEAVGID----KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG-------------------------------------------------------PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
37 PsiBlast_CBE 69.2746%-123 - C6 -3CP9 B:[5-301] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--A--TC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKV--------------------------------------------------------KDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
94 PsiBlast_CBE 69.1443%-117 - C6 -4J97 ? D:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPL-----GQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PP------------------------------------------------------RVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
86 PsiBlast_CBE 69.1143%-124 - C6 -4J99 FGFR2_HUMAN A:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------P------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDIN--DYYKT--NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
74 PsiBlast_CBE 69.0444%-113 - C6 -1FGI FGFR1_HUMAN A:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
34 PsiBlast_CBE 69.0246%-119 - C6 -3CPC VGFR2_HUMAN A:[6-308] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
104 PsiBlast_CBE 68.9443%-122 - C6 -4J95 ? B:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------P------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKNTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
73 PsiBlast_CBE 68.9444%-122 - C6 -1FGI B:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
105 PsiBlast_CBE 68.9043%-121 - C6 -4J95 FGFR2_HUMAN A:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------P------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI----YYKNTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
36 PsiBlast_CBE 68.9046%-118 - C6 -3CPB VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
56 PsiBlast_CBE 68.8844%-114 - C6 -3RHX FGFR1_HUMAN A:[5-295] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQ----------------------------------------------------
52 PsiBlast_CBE 68.8744%-118 - C6 -4K33 A:[25-314] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAD-P----------KWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKD--R--AAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-GGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTS------------------------------------------------EQ---------LTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLV----EDLDRVLTVT-------------------------------------------------------
48 PsiBlast_CBE 68.8445%-124 - C6 -3EFL B:[7-301] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--A--TC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYK-----------------------------------------------------------F---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
42 PsiBlast_CBE 68.7546%-118 - C6 -3B8Q B:[6-302] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK--------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA------------------------------------------------------------
64 PsiBlast_CBE 68.7344%-118 - C6 -4F65 FGFR1_HUMAN A:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLD--KPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-----------PE--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF----------YYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
95 PsiBlast_CBE 68.7243%-117 - C6 -4J97 ? C:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLG---FGQVVMAEAVGID-------EA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PP----------------------------------------------------INRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
135 HHSearch 68.6454%-113 - C6 -2XIR A:[14-311] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYD-AS---------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPY------------------------------------------------------------YKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELV----EHLGNLLQANA------------------------------------------------------
92 PsiBlast_CBE 68.5943%-116 - C6 -3GQL FGFR1_HUMAN B:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-----------PE--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR----------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
136 HHSearch 68.5346%-110 - C6 -2IVS RET_HUMAN A:[14-311] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED-P----------KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGR--A--GY--TTVAVKMLKENASPSELRDLLSEFNVLKQV-NHPHVIKLYGACSQ-DGPLLLIVEYAKYGSLRGFLRESRKV--GP---------------------GYL--------------------------------------RALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP-ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADIS----KDLEKMMVKR-------------------------------------------------------
85 PsiBlast_CBE 68.4743%-124 - C6 -4J99 ? D:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR---------------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKT---GRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
33 PsiBlast_CBE 68.4746%-122 - C6 -3CPC B:[6-301] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--A--TC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVP----------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
38 PsiBlast_CBE 68.4546%-115 - C6 -3CP9 VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
68 PsiBlast_CBE 68.3544%-116 - C6 -4F63 FGFR1_HUMAN A:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPL-----GQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
67 PsiBlast_CBE 68.2844%-121 - C6 -4F63 B:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGA-GQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
49 PsiBlast_CBE 68.2745%-110 - C6 -3EFL VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGID-------TC--RTVAVKMLKE--THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG-------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
46 PsiBlast_CBE 68.1846%-114 - C6 -2QU5 A:[5-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA-------------DARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQ--------------------------------------------------------
76 PsiBlast_CBE 68.0644%-117 - C6 -1AGW FGFR1_HUMAN A:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPL-----GQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
103 PsiBlast_CBE 68.0543%-120 - C6 -4J95 ? C:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR---------------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKNTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
102 PsiBlast_CBE 68.0343%-119 - C6 -4J95 ? D:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR---------------------------------------------------------------------QMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-----------GRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
22 PsiBlast_CBE 68.0246%-105 - C6 -3U6J A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID----A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHH----------------------------------------------------
50 PsiBlast_CBE 67.9145%-124 - C6 -2P2I B:[6-304] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLGR---GQVIEADAFGIDKT--A--TC--RTVAVKML----THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYK-----------------------------------------------------------F---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF--------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
32 PsiBlast_CBE 67.9146%-113 - C6 -3DTW VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDK------TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
72 PsiBlast_CBE 67.9044%-119 - C6 -2FGI FGFR1_HUMAN A:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPL-----GQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP----------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-DIHHIDYYKKT-NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
91 PsiBlast_CBE 67.8943%-121 - C6 -3GQL C:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP---------------------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR----------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQEY--------------------------------------------------
39 PsiBlast_CBE 67.8646%-111 - C6 -3BE2 A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID-------TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG-------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHH--------------------------------------------------
83 PsiBlast_CBE 67.8243%-112 - C6 -4J96 FGFR2_HUMAN B:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG-------------MEYSY--------------------------------DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKMTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLTTN-----------------------------------------------------
93 PsiBlast_CBE 67.8043%-112 - C6 -3GQL FGFR1_HUMAN A:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP---------------------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR------------NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQEYLDLSMPLD------------------------------------------
65 PsiBlast_CBE 67.6944%-120 - C6 -4F64 B:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
30 PsiBlast_CBE 67.6844%-108 - C6 -3VO3 A:[9-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLD-EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRN--------------------------------------------EFVPYK----DLYKDF---------LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
80 PsiBlast_CBE 67.6544%-108 - C6 -3JS2 FGFR1_HUMAN A:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGL-------HNPE--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
44 PsiBlast_CBE 67.5546%-110 - C6 -2RL5 A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGR---GQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL--------------DARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHH---------------------------------------------------
71 PsiBlast_CBE 67.4444%-119 - C6 -2FGI B:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
63 PsiBlast_CBE 67.4144%-118 - C6 -4F65 B:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLD--P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRP-----------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF-------HIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSN-----------------------------------------------------
23 PsiBlast_CBE 67.4146%-109 - C6 -3EWH A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID-------TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLAR----DPDYVR-----LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHH--------------------------------------------------
89 PsiBlast_CBE 67.3943%-113 - C6 -2PZP B:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPL------QVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEEDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG--------------------------------------------------------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLTTN-----------------------------------------------------
98 PsiBlast_CBE 67.2943%-111 - C6 -4J98 FGFR2_HUMAN B:[23-313] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------KWEFPRDKLTLGKPLGEGAFGQVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------PPG-------------MEYSY--------------------------------DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKQTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLT-------------------------------------------------------
31 PsiBlast_CBE 67.2744%-109 - C6 -3VNT A:[9-315] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLD-EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRN--------------------------------------------EFVPYK------YKDF---------LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
81 PsiBlast_CBE 67.2344%-120 - C6 -3TT0 B:[57-347] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA-----------------PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSN-----------------------------------------------------
75 PsiBlast_CBE 67.2244%-121 - C6 -1AGW B:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
55 PsiBlast_CBE 67.2144%-119 - C6 -3RHX B:[5-295] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---P-N--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARR------------------------------------------------------------Q---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA------DYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
47 PsiBlast_CBE 67.1146%-114 - C6 -2P2H A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGR----QVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLAR---------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHH---------------------------------------------------
82 PsiBlast_CBE 67.0144%-103 - C6 -3TT0 FGFR1_HUMAN A:[57-347] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPE--------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
28 PsiBlast_CBE 66.8845%-110 - C6 -4AG8 A:[11-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPY---------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
29 PsiBlast_CBE 66.8445%-111 - C6 -2XIR A:[11-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPY---------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
90 PsiBlast_CBE 66.7143%-116 - C6 -2PZP FGFR2_HUMAN A:[24-313] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------KWEFPRDKLTLGKPL------QVVMAEAVGIDKD--KPKEA--VTVAVKMLKDDATEEDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLRARR--------P----------------------------------------------------------EEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRILTLTTN-----------------------------------------------------
79 PsiBlast_CBE 66.3144%-109 - C6 -3JS2 B:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPN--RV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP---------------------------------------------------------EQ---------LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
25 PsiBlast_CBE 66.1543%-106 - C6 -4ASD A:[39-350] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPDELPLD-EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--A--TC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPY---------------------------------------------------------YKDF---LTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
119 HHSearch 65.6737%-109 - C6 -4AOJ NTRK1_HUMAN A:[33-322] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-C----------VHHIKRRDIVLKWELGEGAFGKVFLAECHNLLP-------K--MLVAVKALKE-ASESARQDFQREAELLTML-QHQHIVRFFGVCTE-GRPLLMVFEYMRHGDLNRFLRSHGPD-----------------------------------------------------------------PGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFG----------------TMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS-NTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVH----ARLQALAQA---PP---------------------------------------------------
129 HHSearch 62.0243%-102 - C6 -1QCF HCK_HUMAN A:[180-454] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-D----------AWEIPRESLKLEKKLGAGQFGEVWMATYNK----------H--TKVAVKTMKPGS--MSVEAFLAEANVMKTL-QHDKLVKLHAVVT--KEPIYIITEFMAKGSLLDFLKSDE-------------------------------------------------------------------GSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIE-DNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMS-NPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQ----SVLDDFYT--ATESQYEEIP---------------------------------------------
10 PsiBlast_PDB 58.3650% -70 - C6 -3G0E A:[4-331] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSA----------------HLTEREALMSELKVLSY-LGNHM---------NIVNLL--GACTIGGPTLVITEYCCYG-DLLNF-LRRK---RDSFICSKTSPAIMEDDELALDLEDLLS-------------------FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQISES-------------------------------------------------------
11 PsiBlast_PDB 57.3250% -69 - C6 -3G0F ? A:[25-331] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSA----------------HLTEREALMSELKVLSY-LGNHM---------NIVNLL--GACTIGGPTLVITEYCCYG-DLLNF-LRRK---RDSF----------------LDLEDLLS-------------------FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARHIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQISE--------------------------------------------------------
21 PsiBlast_CBE 57.2750% -71 - C6 -3G0F ? B:[23-331] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGNNYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSA----------------HLTEREALMSELKVLSY-LGNHM---------NIVNLL--GACTIGGPTLVITEYCCYG-DLLNF-LRRK---RDSF----------------LDLEDLLS-------------------FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARHIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQISE--------------------------------------------------------
16 PsiBlast_PDB 57.2450% -71 - C6 -1T46 A:[1-308] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNNYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSA----------------HLTEREALMSELKVLSY-LGN---------HMNIVNLL--GACTIGGPTLVITEYCCYG-DLLNF-LRRK---RDSF--------------LALDLEDLLS-------------------FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQISESTN-----------------------------------------------------
14 PsiBlast_PDB 55.9150% -69 - C6 -1PKG KIT_HUMAN A:[19-321] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYVYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--D--AA--MTVAVKMLKPSA----------------HLTEREALMSELKVLSY-LGN---------HMNIVNLL--GACTIGGPTLVITEYCCYG-DLLNF-LRRK---RDSFICSK-----------ALDLEDLLS-------------------FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIV----QLIEKQ-----------------------------------------------------------