@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0239: (2015-11-29 )
MEQDKKGDISSKESTSILGKAKNAALGVRGFLIEGGKILFKGVGRGLFVLFKGTIIYPFQLKSQLKSWDEMWHDIKNGWRYVIGKIPKEYYLPIKTTQASEDLGVHITEQEKGKGGVIFKASRTLVGDIPYLSQEQLDQIKNNLPSVTIFRKKNEAIIEVDVKEITNGIKAGPEYKGKSPEEVKQLIIGKIYDKVNENLKGLAEITGGEFKVHTDQKLLYGIAEKLYRWYREQPSEVVKPIEKSPESNEFITQSNMTDPLGMYHVKAGKTTSKGIELEDKLREAIGNESNLRFEGDVSNSKMESPSSTPVLNPGREKGGRASKA
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10-..--.------.....20........30---------..-..--....40...-.-..-----..50.-------..------...----.-.60...-.....70--------........80..---...-...90......----.-.100------..---.....-110----...-.------....120.....---..130......-.140-----------...----..-------..-.150----...--....----.160------.......-----------.170.......180....---..------..190---.......200.......-..210...-....220.--......230.......240.-......250....-...260-..----..---....270-....-.....280.......290........300.------.......310........320..-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEQDKKGDISS-KE--
S
------
T
S
I
LGKAKN
A
A
LG
V
R
G
F
---------
L
I-EG--
G
K
I
L
F
K
GVG-R-
G
L
-----
F
V
L
F
K-------
G
T
------
I
I
Y
----
P
-
F
Q
L
K
S
Q
-
L
K
S
W
D
E
M
--------
W
H
D
I
K
N
G
W
R
Y
V
I
---GKI-PK
E
Y
Y
L
P
I
KTT----Q-ASED------L
G
---
V
H
I
T
E-QE-----KGK-G------
G
V
I
F
K
ASR
T
L
VG---DIPYL
S
Q
E
Q
L
D
-
Q
I
K
------------NNL----P
S
-------
V
T
-
I
F
R
-----KKN--
E
A
I
I
----
E
V
D
-------
V
K
E
I
T
N
G
-----------
I
KAGPEYKGK
S
P
E
-
E
V
K
Q
---
L
I
------
I
G
K
I
Y
---
D
K
V
N
E
N
L
K
--
G
L
A
E
ITG-G
E
F
K
V
HT
D
-
Q
K
L
L
Y
G
I
A
--
E
K
L
Y
R
W
Y
R
E
Q
P
S
E
V
V
K
P
I
EK-SPESN
E
F
I
TQSNM-TDPL-
G
-
M
Y
----
H
V
---KAGKT---TSKG-I
E
L
E
D
K
L
R
E
AIGNES
N
-
L
R
F
EGDVSNSK-M------ESPSSTPVL-NPGREKGGRASKA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
72.33
21%
9
- C4 -
4Z24
1
YR135_MIMIV
A:
[4-652]
----------------------------------------------------------------------------------------------------------------------------------------------NLTGD
I
V
I
I
G
AG
A
A
G
S
L
L
A
H
Y
L
A
R
F
S
N
M
K
I
I
L
L
E
AGHSHFNDPVVTDPMGFFGKYNPPNENIS
M
S
Q
N
P
S
Y
S
W
Q
G
-
A
Q
EP
N
------
T
G
A
Y
G
N
R
P
I
I
A
H
G
-
M
G
F
-------------
G
--
G
S
T
M
I
N
R
------
L
-----
N
L
V
V
G
-------
G
R
------
T
V
F
----
D
-
N
D
W
P
V
G
-
W
K
-------------
Y
D
D
V
K
N
Y
F
R
R
V
L
---
V
D
I
N
P
V
R
D
N
T
K
A
S
I
T
----
S
-
V
A
L
D
------
A
L
---
R
I
I
A
E
-
Q
Q
-----
I
A
S
-
G
------
E
P
V
D
F
L
L
N
K
A
T
G
---
N
V
P
N
V
E
K
T
T
P
D
-
A
V
P
------------
L
N
L
----
N
D
-----------
Y
E
-----
G
V
N
--
S
V
V
A
F
S
S
F
Y
M
G
-------
V
N
Q
L
S
D
G
-------------------------
N
Y
I
R
---
K
Y
------
A
G
N
T
Y
LNR
N
Y
V
D
E
N
G
R
--
G
I
G
K
F
S
G
---
L
R
V
V
S
D
------
A
V
V
--
D
R
I
I
--
F
K
G
N
R
A
V
G
V
N
Y
I
D
R
-
E
G
I
M
H
Y
V
K
V
N
K
E
V
-
V
V
T
S
-
G
-
A
F
----
Y
T
---
P
T
I
L
Q
---
R
S
------------
G
I
G
D
F
T
Y
-
L
S
S
I
G
-
V
K
N
L
V
-
Y
------
N
N
P
L
V
------------
G
T
G
L
K
N
H
Y
S
P
V
T
I
T
R
V
H
G
E
P
S
E
V
S
R
F
L
SNMAANPTNMGFKGLAELGFHRLDPNKPANANT
V
T
Y
R
K
Y
Q
L
M
M
T
A
G
VGIP
A
E
Q
Q
Y
L
S
GLSPSSNN
L
F
T
L
I
ADDIRFA
P
E
G
Y
I
K
I
GTPNIPRDVP
K
I
F
F
N
T
F
V
T
Y
T
P
T
SAPADQQ
W
P
I
A
Q
K
T
L
A
P
L
I
S
A
L
L
G
Y
D
I
I
Y
Q
T
L
M
S
M
N
Q
T
A
R
D
S
GFQ
V
S
L
E
MVYPL
N
D
L
I
Y
K
L
H
N
G
L
A
T
YGANWWHYFVPTLVGDDT
P
A
G
R
E
F
A
D
T
L
S
K
L
S
Y
Y
P
R
VG
A
H
L
D
SHQGCSCSIGRTVDSNLKVIGTQ
N
V
R
V
A
D
LSAAAFPPGGNT
W
A
T
A
S
M
I
G
A
R
A
V
D
L
I
L
GFPYLRDLPVND
V
P
I
L
N
VN
35
Fugue
62.64
16%
18
* C3 *
5A5T
-
?
A:
[7-605]
RP
E
N
A
L
K
R
A
N
E
F
L
E
VG
K
K
Q
P
A
L
D
V
L
Y
D
V
M
K
S
KKHR
T
W
Q
K
I
H
E
P
I
M
L
K
Y
L
E
L
C
V
D
L
R
KSH
L
A
K
E
G
L
Y
Q
Y
K
N
I
CQQV
N
I
K
S
L
E
D
V
V
R
A
Y
L
K
L
A
E
E
K
T
E
A
A
K
E
E
S
Q
Q
M
V
L
D
I
E
D
LDNIQ
T
P
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S
V
L
L
S
A
V
SGEDTQD
R
T
D
R
L
L
L
T
P
W
V
K
F
L
W
E
S
Y
R
Q
C
L
D
LLRN
N
S
R
V
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R
L
Y
H
D
I
A
Q
Q
A
F
K
F
C
L
Q
YT
R
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A
E
F
R
K
L
C
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N
L
R
M
H
L
S
Q
I
Q
R
H
H
N
Q
S
T
A
I
N
L
N
N
-
P
E
--
S
------
Q
S
M
H
L
E
T
R
L
V
Q
L
D
-
S
A
I
---------
S
M
-
E
L
--
W
Q
E
A
F
K
A
V
E
-
D
-
I
H
-----
G
L
F
S
L
-------
S
K
------
K
P
P
----
K
-
P
Q
L
M
A
N
-
Y
Y
N
K
V
S
T
--------
V
F
W
K
S
G
N
A
L
F
H
A
---
S
T
L
-
H
R
L
Y
H
L
S
R
E
M
R
----
K
-
N
L
T
---------------
Q
D
-
E
M
-----
Q
R
M
-
S
------
T
R
V
L
L
A
T
L
S
-------
I
P
I
T
P
E
R
T
D
I
-
A
R
L
------------
L
D
M
----
D
G
-------
I
I
-
V
E
K
-----
Q
R
R
--
L
A
T
L
----
L
---------------
G
-----------
L
Q
A
P
P
T
R
I
G
L
I
N
D
-
M
V
R
F
-------------
N
V
L
---
Q
Y
V
V
P
E
V
K
--
D
L
Y
N
W
L
E
-
V
E
F
----
N
-
P
L
K
L
C
E
R
V
--
T
K
V
L
N
W
V
R
E
Q
P
-------
E
K
-
E
P
E
L
Q
Q
Y
V
P
Q
L
Q
S
-
N
T
I
L
-
R
-
L
L
----
Q
Q
---
V
A
Q
I
Y
---
Q
S
I
E
----
F
S
R
L
T
S
L
V
P
F
V
D
A
-
F
Q
L
E
R
A
I
V
D
A
A
-
R
H
CDLQV
R
I
D
H
T
S
R
T
L
-
S
F
G
S
D
L
N
Y
A
T
R
E
D
APIGPHLQSMPSEQIRNQ
L
T
A
M
S
S
V
L
A
K
A
L
E
V
I
K
PA
H
I
L
Q
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K
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Q
H
Q
L
A
V
T
A
Y
L
K
N
S
R
K
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L
A
R
R
Q
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I
E
E
R
K
E
R
L
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S
L
N
I
Q
R
E
K
E
E
L
E
Q
R
E
A
E
L
Q
K
V
R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
62.29
17%
5
- C5 -
4R1D
-
?
B:
[1-301]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
K
T
G
W
--------
I
------
T
H
C
F
G
R
----------
F
---------
L
I
-
D
L
--
P
P
---
D
A
V
I
-
N
-
A
G
-----
Y
Y
L
W
G
-------
D
R
------
I
E
Y
LDDK
P
-
T
E
L
A
A
R
-
V
D
R
L
E
Q
E
--------
W
R
T
Q
R
H
K
------------
S
K
G
N
M
F
L
R
K
I
D
----
F
-
G
N
E
S
------
V
G
---
L
L
S
W
S
-
S
E
-----
V
---------------
A
S
K
T
Y
L
L
---
D
T
Y
V
T
S
K
---------------------------
P
T
-------
W
H
-
V
Y
R
-----
W
K
G
--
K
V
S
V
----
D
R
E
-------
Q
H
A
V
E
I
S
-----------
R
A
L
A
R
N
L
R
S
R
A
P
K
-
E
I
P
S
E
P
G
F
C
------
I
D
H
A
Y
---
I
-
A
G
D
S
F
Q
--
V
E
R
F
G
V
G
-
V
T
F
P
E
H
P
G
-
A
R
F
E
F
R
S
S
T
G
A
E
L
N
S
L
L
E
R
V
D
G
F
V
Q
N
M
L
S
T
-
F
A
G
M
E
T
L
R
K
G
K
H
P
-
V
G
S
L
P
G
-
E
E
----
Y
L
---
V
A
G
S
D
KG
Q
R
G
Y
T
-
F
M
W
E
V
Q
G
K
E
E
S
L
T
E
P
N
-
L
T
A
G
L
A
V
L
E
R
S
-
N
------
E
N
G
K
P
P
P
P
A
-
F
K
S
D
K
E
A
L
E
L
W
D
T
I
V
D
S
IRVRPTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
62.22
15%
13
- C2 -
3KDR
2
?
A:
[7-297]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
T
T
-
R
A
--
E
------
A
L
T
I
P
A
V
L
R
A
R
N
L
L
S
T
T
---------
V
A
-
R
T
---
P
L
V
C
D
G
T
L
-
P
-
P
F
-----
V
P
V
A
A
-------
P
P
------
G
A
A
----
T
M
Q
T
P
F
H
R
M
L
A
T
A
D
D
L
--------
L
F
N
G
V
A
C
W
A
L
D
R
D
ES
G
T
C
-
I
G
A
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I
P
L
D
T
W
----
Q
-
I
E
E
N
-------
T
---
V
R
V
N
G
-
K
A
-----
V
D
P
M
E
------
V
C
I
F
V
G
I
H
---
G
---
G
L
L
T
H
A
S
E
T
F
T
-
D
A
R
------------
N
L
V
----
R
A
-------
A
A
-
R
V
A
-----
Q
N
P
--
A
A
L
I
----
E
L
R
-------
Q
---
T
N
N
------------------
A
Q
L
S
P
D
-
D
V
D
R
---
I
I
------
N
G
Y
V
A
---
A
R
R
G
R
N
-
S
--
G
V
G
F
S
S
S
-
G
L
E
V
H
E
H
E
M
A
K
-----
E
--
N
L
L
I
E
G
R
N
A
A
A
V
D
V
A
R
A
-----------------
M
N
V
P
A
-
A
-
F
I
----
D
A
---
T
V
G
Q
N
---
A
A
S
R
M
I
E
L
V
T
-----
F
G
V
E
P
L
M
S
A
I
E
A
R
L
N
Q
P
D
M
H
------
A
D
H
L
A
N
P
L
K
F
D
P
A
A
L
L
D
A
I
P
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
59.80
19%
0
- C1 -
1A6Q
3
PPM1A_HUMAN
A:
[2-368]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
F
L
D
K
P
K
M
E
K
-
H
N
--
A
------
Q
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
W
---------
R
V
-
E
M
E
D
A
H
T
A
V
I
G
L
P
-
S
-
G
L
ES
W
S
F
F
A
V
Y
D
-------
G
H
AGS
Q
V
A
K
Y
C
----
C
-
E
H
L
L
D
H
-
I
T
N
N
Q
D
F
KGSAGAPS
V
E
N
V
K
N
G
I
R
T
G
F
---
L
E
I
--
D
E
H
M
R
V
M
S
E
K
----
K
-
H
G
A
D
R
S
G
S
T
A
V
G
---
V
L
I
S
P
-
Q
H
T
Y
F
I
N
C
G
D
-
S
------
R
G
L
L
C
R
N
R
K
V
H
F
F
T
Q
D
H
K
P
S
N
P
L
E
K
E
-
R
I
Q
------------
N
A
G
----
G
S
-------
V
M
-
I
Q
R
VNGSL
A
V
S
--
R
A
L
G
----
D
F
D
-------
Y
K
C
V
H
G
K
--------------
G
P
T
E
Q
L
V
S
P
E
P
E
V
H
D
---
I
E
---------------
R
S
E
E
D
D
Q
--
F
I
I
L
A
C
D
-
G
I
W
D
V
M
G
N
-
E
E
L
C
D
F
V
R
--
S
R
L
---------
E
V
T
D
D
L
E
K
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
-
R
D
N
M
-
S
-
V
I
----
L
I
C
F
P
N
A
P
K
V
---
S
P
E
A
-
V
K
K
E
A
E
L
D
K
Y
L
E
C
R
V
E
-
E
I
I
K
G
V
P
D
L
V
H
-
V
------
M
R
T
L
A
S
E
N
I
-
P
S
L
P
P
G
G
E
L
A
S
K
R
N
V
I
E
A
V
Y
N
R
L
N
PY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
55.85
22%
-47
- C6 -
3UEB
-
?
A:
[15-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
E
L
S
E
E
Q
L
I
-
E
I
G
E
L
A
Q
E
T
I
I
D
Y
V
F
D
H
L
----
T
R
SEVK
D
I
E
V
T
M
R
I
N
-----
R
E
E
--
T
L
D
L
----
E
I
E
-------
V
Y
L
E
V
P
-----------------
I
F
V
K
V
D
V
D
-
K
L
I
D
---
E
A
------
V
E
R
A
Y
---
E
I
V
E
R
K
L
R
--
E
I
A
N
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
55.13
12%
1
- C4 -
3JZ0
6
?
A:
[22-287]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
Q
-
K
E
--
L
------
I
A
N
V
K
N
L
T
E
S
D
E
R
I
T
A
C
---------
M
M
-
Y
G
------------------------------------------------------
S
F
-
T
K
G
E
G
D
Q
--------
Y
S
D
-----
I
E
F
Y
---
I
F
L
-
K
H
S
I
T
S
N
F
D
S
S
----
N
-
W
L
F
D
------
V
A
---
P
Y
L
M
L
-
Y
K
-----
N
E
Y
-
G
------
T
E
V
V
I
F
D
N
L
I
R
G
---
E
F
H
F
L
S
E
K
D
M
N
-
I
I
P
------------
S
F
K
----
D
S
-------
G
Y
-
I
P
D
-----
T
K
A
--
M
L
I
Y
----
D
E
T
-------
G
Q
L
E
N
Y
L
-----------
S
E
I
S
G
A
R
P
N
R
L
T
E
-
E
N
A
N
---
F
L
------
L
C
N
F
S
---
N
L
W
L
M
G
I
N
--
V
L
K
R
------
G
E
Y
A
R
S
-
L
E
L
L
S
Q
L
Q
--
K
N
T
L
Q
L
I
R
M
A
E
K
N
A
D
N
W
L
N
M
-
S
K
N
L
E
K
E
I
S
L
E
N
Y
-
K
K
F
A
-
K
-
T
T
ARLD
K
V
---
E
L
F
E
A
---
Y
K
N
S
-
L
L
L
V
M
D
L
Q
S
H
L
I
E
Q
Y
N
-
L
K
V
T
H
D
I
L
E
R
L
-
L
------
N
Y
I
S
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
54.43
30%
13
- C6 -
4GRS
2
AROF_THEMA
A:
[23-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
N
------
L
K
---
C
H
I
S
K
G
Q
E
-----
R
T
V
-
I
------
G
I
I
-
G
D
D
R
Y
V
V
A
---
D
----
K
F
E
S
L
D
-
C
V
E
------------
S
V
V
R
V
LK
P
Y
-------
K
L
-
V
S
R
-----
E
F
H
P
E
D
T
V
I
----
D
L
G
-------
D
V
K
I
G
N
G
YF
T
--------
I
I
A
G
P
----
C
S
I
E
-
S
R
D
Q
---
I
M
---------------
K
V
A
E
F
L
A
E
V
G
I
K
V
L
R
G
-
G
A
F
K
P
R
T
S
-
P
Y
S
F
Q
G
Y
G
--
E
K
A
L
R
W
M
R
E
A
A
D
E
Y
G
L
V
T
V
T
-
E
V
M
D
T
R
H
V
E
L
V
A
K
-
Y
S
D
I
-
L
-
Q
I
----
G
A
---
R
N
S
Q
N
---
F
E
L
L
-
K
E
V
G
K
V
E
N
P
V
L
L
K
R
G
M
-
G
N
T
I
Q
E
L
L
Y
S
A
-
E
------
Y
I
M
A
Q
G
N
E
N
-
V
I
L
C
E
R
G
I
R
T
F
E
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
54.00
24%
-47
* C4 *
2WB6
2
Y102_AFV1Y
A:
[11-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
--
S
------
T
S
L
Y
K
K
A
G
S
E
N
L
Y
F
Q
G
I
VDKN
K
I
V
I
P
M
S
-
E
F
--
L
D
S
M
F
L
V
I
E
-
K
L
G
V
-----
H
A
E
K
K
-------
G
S
------
M
I
F
----
L
-
S
S
E
R
V
K
-
L
A
D
W
K
Q
L
--------
G
A
M
C
S
D
C
Y
---
H
---
C
K
L
-
P
L
S
S
F
I
E
I
V
T
R
----
K
-
A
K
D
K
------
F
L
---
V
M
Y
N
E
-
K
E
V
T
L
--
V
A
R
-
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
53.86
10%
19
- C3 -
3MSV
-
ETT1_SCHPO
A:
[13-392]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A
S
L
K
K
Q
Q
Q
L
E
K
Q
K
Q
E
A
S
Y
E
L
S
E
E
D
N
--
I
------
S
Q
L
W
G
L
Y
E
M
S
R
E
K
L
E
N
D
---------
D
I
-
D
A
--
S
V
S
L
V
F
G
T
I
-
H
-
E
A
-----
D
R
I
L
R
-------
N
T
-------------------
E
D
-
I
S
T
L
P
K
D
--------
F
H
A
A
Y
S
S
A
L
L
A
V
---
S
E
L
-
F
E
I
A
Q
K
R
L
K
E
T
----
N
T
E
E
S
Y
------
I
D
---
A
A
I
E
R
-
A
Q
-----
L
G
L
-
D
APGNE
S
R
L
F
L
A
L
A
R
A
Y
L
E
---
K
V
R
V
L
V
W
R
H
D
N
E
E
S
L
------------
A
N
I
----
P
V
-------
T
Q
-
L
V
N
-----
P
Y
I
--
E
K
A
I
----
Q
Y
L
-------
R
P
L
A
Q
D
S
TEYFDALTPDS
L
R
P
L
Y
I
L
S
S
Y
L
F
Q
-
F
G
D
Q
---
F
S
------
E
A
F
L
L
---
D
V
C
S
I
I
T
A
--
L
W
L
K
S
V
V
-
D
P
N
T
P
A
Y
Y
-
K
L
I
A
Q
E
A
V
--
L
N
N
Y
T
T
F
A
E
Y
Y
M
D
L
L
D
N
S
E
S
-
N
V
D
D
L
I
N
K
A
S
S
W
L
-
N
N
S
V
-
D
-
T
W
----
N
V
---
I
Y
T
L
D
---
K
S
P
-----
E
R
L
L
K
L
A
D
I
K
M
D
L
-
A
Q
I
V
Q
D
E
A
S
Q
D
-
N
------
Y
L
K
E
A
C
N
A
I
-
K
E
A
Q
G
S
G
V
E
L
S
P
D
Y
V
E
F
V
E
A
Y
S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
52.67
15%
11
- C3 -
3C8F
3
PFLA_ECOLI
A:
[1-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
I
G
R
I
H
S
-
F
E
--
S
------
C
G
T
V
D
G
P
-----
G
I
R
F
I
---------
T
F
F
Q
G
--
C
L
M
R
C
L
Y
C
H
N
R
-
D
T
-----
W
D
T
H
G
-------
G
K
------
E
V
T
----
V
-
E
D
L
M
K
E
-
V
V
T
Y
R
H
F
--------
M
N
A
S
G
G
G
V
T
A
S
G
---
G
E
A
-
I
L
Q
A
E
F
V
R
D
W
F
----
R
-
A
C
K
K
------
E
G
---
I
H
------------------------------
T
C
L
D
---
T
N
G
F
V
R
R
Y
D
-
P
-
V
I
D
------------
E
L
L
----
E
V
-------
T
D
----------------
L
V
----
M
L
D
-------
L
K
Q
M
N
-------------------------
D
-
E
I
H
Q
---
N
L
------
V
G
V
S
N
---
H
R
T
L
E
F
A
K
--
Y
L
A
N
K
--------
N
V
K
-
V
W
I
R
Y
V
V
V
--
P
G
W
------------------
S
D
D
D
D
S
A
H
R
L
G
E
F
-
T
R
D
M
-
G
N
V
E
----
K
I
---
E
L
L
P
Y
---
H
E
L
G
-
K
H
K
W
V
A
M
------
G
E
E
-
Y
K
L
D
G
V
K
P
P
K
K
-
E
------
T
M
E
R
V
K
G
I
L
-
E
Q
Y
G
H
K
V
M
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
50.77
10%
-1
* C5 *
4DVZ
-
CAGA_HELPY
A:
[308-829]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
G
S
H
N
G
K
V
S
L
-
L
Y
--
A
GDKHD
W
N
A
T
V
G
Y
K
D
N
V
A
T
L
I
N
V
H
---------
M
K
-
N
G
--
S
G
L
V
I
A
G
G
E
-
K
-
G
I
NN
P
S
-
F
Y
L
Y
K
E
D
QLTG
S
Q
R
------
A
L
S
----
Q
-
E
E
I
R
N
K
-
V
D
F
M
E
F
L
--------
A
Q
N
N
T
K
L
D
N
L
S
E
---
K
E
K
-
E
K
F
Q
N
E
I
E
D
F
Q
K
DS
K
A
-
Y
L
D
A
------
L
G
N
D
R
I
A
F
V
S
-
K
K
-----
D
T
K
-
H
------
S
A
L
I
T
E
F
N
N
G
D
L
---
S
Y
T
L
K
D
Y
E
K
N
V
-
T
L
Q
------------
G
S
L
----
K
H
-------
D
G
-
V
M
F
V
D
Y
S-
F
N
K
--
V
A
V
F
----
N
L
P
DLNNLAI
T
S
F
V
R
R
N
-----------
L
E
N
K
L
T
A
K
G
L
S
L
Q
-
E
A
N
K
---
L
I
K
D
F
L
S
S
N
K
E
L
A
---
G
K
A
L
N
F
N
K
--
A
V
A
E
A
K
S
T
G
N
Y
D
E
V
K
K
-
A
Q
K
D
L
E
K
S
--
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
G
-
N
K
K
A
Q
A
N
S
Q
K
D
E
I
-
F
A
L
I
-
N
-
K
E
----
A
N
---
R
D
A
R
A
---
I
A
Y
T
-
Q
N
L
K
G
I
K
R
E
L
S
D
K
L
E
K
-
I
S
K
D
L
K
D
F
S
K
S
-
F
------
D
E
F
K
N
F
S
K
A
-
E
E
T
L
K
A
L
K
G
S
V
K
D
L
GIN
P
E
W
I
S
K
V
E
N
L
N
A
A
L
N
E
F
K
N
GDF
S
K
V
T
Q
A
K
S
D
L
E
N
S
V
K
D
V
I
I
N
Q
K
V
T
D
K
V
D
N
L
N
Q
A
V
S
V
A
K
A
M
GDF
S
R
V
E
Q
V
L
A
D
L
K
N
F
S
K
E
Q
L
A
Q
Q
A
Q
K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
40.23
23%
-9
* C7 *
1JBJ
-
A:
[127-182]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
C
G
L
T
--
D
K
T
I
K
W
L
K
D
--
G
S
I
I
S
P
L
N
A
-
T
--
K
N
T
W
N
L
G
N
N
A
-
K
D
P
R
-
G
-
T
Y
----
Q
C
---
Q
G
A
K
E
---
T
S
N
P
-
L
Q
V
Y
Y
R
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
40.22
26%
39
- C7 -
3FG6
1
ADSV_HUMAN
A:
[127-212]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
V
S
----
Q
-
G
K
E
P
-----------
V
H
L
L
S
-
L
F
-----
K
D
K
-
P
------
L
I
I
Y
-----------------
P
T
R
L
F
-
Q
V
R
------------
R
N
L
----
A
S
-------
I
T
---------------
R
I
V
----
E
V
D
-------
V
D
--
A
N
S
-----------
L
N
S
N
D
V
F
V
L
K
L
P
Q
-
N
S
G
Y
---
I
W
------
V
G
K
G
A
---
S
Q
E
E
E
K
G
A
--
E
Y
V
A
S
V
L
-
K
C
K
T
L
R
I
Q
-
E
G
E
E
P
E
E
F
--
W
N
S
L
G
G
K
K
D
Y
Q
T
S
P
L
L
E
T
Q
A
-
E
D
H
P
P
R
L
Y
G
C
S
N
K
-
T
G
R
F
-
V
-
I
E
----
E
I
---
P
G
E
F
T
---
Q
D
D
L
-
A
E
D
D
V
M
L
L
D
A
W
E
Q
I
F
I
-
W
I
G
K
D
A
N
E
V
E
K
-
K
------
E
S
L
K
S
A
K
M
Y
-
L
T
P
I
V
I
I
K
Q
G
H
E
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
40.10
14%
16
- C6 -
3AEI
2
?
A:
[32-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
E
G
I
I
T
-
S
L
K
-------------------
S
E
-------
R
R
-
I
Y
R
-----
A
F
S
--
D
L
L
V
----
E
I
T
-------
K
D
E
A
I
E
H
-----------
I
E
R
S
R
L
V
Y
K
R
E
I
E
-
K
L
K
K
---
R
E
------
K
E
I
M
E
---
E
L
S
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
39.58
20%
16
- C6 -
3MLG
-
?
A:
[19-84]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
------
D
I
I
F
H
A
S
K
K
L
S
----------
K
K
E
L
E
-
R
L
L
------------
E
L
L
----
A
L
-------
L
E
-
T
F
I
-----
E
K
E
--
D
L
------
E
E
K
-------
F
E
S
F
A
K
A
-----------
L
R
I
D
E
E
L
Q
Q
K
I
E
S
-
R
K
T
D
---
I
V
------
I
Q
S
M
A
---
N
I
L
S
G
G
N
P
--
L
D
K
W
N
D
I
-
I
F
H
A
S
K
K
L
-
S
K
K
E
L
E
R
L
--
L
E
L
L
A
L
L
E
T
F
I
E
K
E
D
L
E
E
K
F
-
E
S
F
A
K
A
L
R
I
D
E
E
L
-
Q
Q
K
I
-
E
-
S
R
----
K
T
---
D
I
V
I
Q
---
S
M
A
N
-
I
L
S
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
39.34
41%
58
- C6 -
2BAM
2
T2BA_BACAM
A:
[61-84]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
C
Y
T
L
L
--
E
D
T
Y
N
W
Y
R
E
K
P
L
D
I
L
K
L
E
K
K
-
K
G
G
P
I
D
V
Y
K
E
F
I
E
-
N
S
E
L
-
K
-
R
V
----
G
M
---
E
F
E
T
G
---
N
I
S
S
-
A
H
R
S
M
N
K
L
L
L
G
L
K
H
G
E
-
I
D
L
A
I
I
L
M
P
I
K
-
Q
------
L
A
Y
Y
L
T
D
R
V
-
T
N
F
E
E
L
E
P
Y
F
E
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
39.19
20%
16
* C6 *
3MLG
-
?
A:
[20-84]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
I
F
H
A
S
K
K
L
S
----------
K
K
E
L
E
-
R
L
L
------------
E
L
L
----
A
L
-------
L
E
-
T
F
I
-----
E
K
E
--
D
L
------
E
E
K
-------
F
E
S
F
A
K
A
-----------
L
R
I
D
E
E
L
Q
Q
K
I
E
S
-
R
K
T
D
---
I
V
------
I
Q
S
M
A
---
N
I
L
S
G
G
N
P
--
L
D
K
W
N
D
I
-
I
F
H
A
S
K
K
L
-
S
K
K
E
L
E
R
L
--
L
E
L
L
A
L
L
E
T
F
I
E
K
E
D
L
E
E
K
F
-
E
S
F
A
K
A
L
R
I
D
E
E
L
-
Q
Q
K
I
-
E
-
S
R
----
K
T
---
D
I
V
I
Q
---
S
M
A
N
-
I
L
S
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
36.91
41%
65
- C6 -
3BAM
1
T2BA_BACAM
A:
[61-84]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
C
Y
T
L
L
--
E
D
T
Y
N
W
Y
R
E
K
P
L
D
I
L
K
L
E
K
K
-
K
G
G
P
I
D
V
Y
K
E
F
I
E
-
N
S
E
L
-
K
-
R
V
----
G
M
---
E
F
E
T
G
---
N
I
S
S
-
A
H
R
S
M
N
K
L
L
L
G
L
K
H
G
E
-
I
D
L
A
I
I
L
M
P
I
K
-
Q
------
L
A
Y
Y
L
T
D
R
V
-
T
N
F
E
E
L
E
P
Y
F
E
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
36.49
41%
59
- C6 -
1BHM
1
T2BA_BACAM
A:
[61-84]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
L
C
Y
T
L
L
--
E
D
T
Y
N
W
Y
R
E
K
P
L
D
I
L
K
L
E
K
K
-
K
G
G
P
I
D
V
Y
K
E
F
I
E
-
N
S
E
L
-
K
-
R
V
----
G
M
---
E
F
E
T
G
---
N
I
S
S
-
A
H
R
S
M
N
K
L
L
L
G
L
K
H
G
E
-
I
D
L
A
I
I
L
M
P
I
K
-
Q
------
L
A
Y
Y
L
T
D
R
V
-
T
N
F
E
E
L
E
P
Y
F
E
L
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------