@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0491: (2015-12-01 )
MVPSVRRSSKSSIVFFLISLVILMLCFAYASVPLYSIFCKATGYGGTTRKVTSATTNIANQKIRVHFNADVMLDLPWKFNSETNYIDTNIGEQSLTFYYVENLSDQPLLGMAVYNVTPFKAGKYFNKVACFCFEEQILLPKQKVAMPVSFYIDPNIMLDDSTKDLSEITLSYTFFKLKQ
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------....-.....10-...---....----.20........30-.......-..40........50........-60........70--........80...-----.....90...---.....100-------------..--......-.------110.....----....120.---......130---..--.-.-.--....140.......150.......160.......170.......-----------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------MVPS-VRRSSK
S
-
S
I
V
---
F
F
L
I
----
S
L
V
I
L
M
L
C
F
A
Y
A--SVP
L
Y
S
I
-
F
CKATGYGGT
T
R
K
V
T
SATTNIA-N
Q
K
I
R
V
H
FNA
D
V
--
M
L
DL
P
W
K
FNSETN-----
Y
I
DTNIGEQ
S
---
L
T
F
Y
Y
V---------------EN--LSDQP
L
-
L
------
G
--
M
A
V
YN----VTPFKAG
K
---
Y
F
N
K
V
A
C
-----
F
C
--
F
-
E
-
E
--QILLPKQKVA
M
P
V
S
F
Y
IDP
N
I
M
LDDSTK
D
L
S
E
I
T
L
S
Y
T
F
F
K
LKQ-----------------------------------------------------------
2
PsiBlast_PDB
94.83
47%
-93
- C4 -
1SP0
-
COXZ_RHIME
A:
[21-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
Q
A
S
D
L
I
L
-
D
E
K
I
K
V
T
F
D
A
N
V
--
A
A
G
L
P
W
E
F
V
P
V
Q
R
-----
D
I
D
V
R
I
G
E
T
V
---
Q
I
M
Y
R
A
---------------
K
N
--
L
A
S
T
P
T
-
T
------
G
--
Q
A
T
F
N
----
V
T
P
M
A
A
G
A
---
Y
F
N
K
V
Q
C
-----
F
C
--
F
-
T
-
E
--
T
T
L
E
P
G
E
E
M
E
M
P
V
V
F
F
V
D
P
E
I
V
K
P
V
E
T
Q
G
I
K
T
L
T
L
S
Y
T
F
Y
P
R
E
P
-----------------------------------------------------------
1
PsiBlast_PDB
94.72
47%
-93
- C4 -
1SO9
-
COXZ_RHIME
A:
[21-145]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
Q
A
S
D
L
I
L
-
D
E
K
I
K
V
T
F
D
A
N
V
--
A
A
G
L
P
W
E
F
V
P
V
Q
R
-----
D
I
D
V
R
I
G
E
T
V
---
Q
I
M
Y
R
A
---------------
K
N
--
L
A
S
T
P
T
-
T
------
G
--
Q
A
T
F
N
----
V
T
P
M
A
A
G
A
---
Y
F
N
K
V
Q
C
-----
F
C
--
F
-
T
-
E
--
T
T
L
E
P
G
E
E
M
E
M
P
V
V
F
F
V
D
P
E
I
V
K
P
V
E
T
Q
G
I
K
T
L
T
L
S
Y
T
F
Y
P
R
E
P
-----------------------------------------------------------
21
HHSearch
93.81
45%
-87
- C4 -
1SO9
-
COXZ_RHIME
A:
[21-149]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
Q
A
-
S
D
L
I
L
D
E
K
I
K
V
T
F
D
A
N
V
--
A
A
G
L
P
W
E
F
V
P
V
Q
R
-----
D
I
D
V
R
I
G
E
T
V
---
Q
I
M
Y
R
A
---------------
K
N
--
L
A
S
T
P
T
-
T
------
G
--
Q
A
T
F
N
----
V
T
P
M
A
A
G
A
---
Y
F
N
K
V
Q
C
-----
F
C
--
F
-
T
-
E
--
T
T
L
E
P
G
E
E
M
E
M
P
V
V
F
F
V
D
P
E
I
V
K
P
V
E
T
Q
G
I
K
T
L
T
L
S
Y
T
F
Y
P
R
E
P
-----------------------------------------------------------
39
Fugue
92.32
43%
-85
- C4 -
1SP0
-
COXZ_RHIME
A:
[21-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
Q
A
S
D
L
I
L
-
D
E
K
I
K
V
T
F
D
A
N
V
--
A
A
G
L
P
W
E
F
V
P
V
Q
R
-----
D
I
D
V
R
I
G
E
T
V
---
Q
I
M
Y
R
A
---------------
K
N
--
L
A
S
T
P
T
-
T
------
G
--
Q
A
T
F
N
----
V
T
P
M
A
A
G
A
---
Y
F
N
K
V
Q
C
-----
F
C
--
F
-
T
-
E
--
T
T
L
E
P
G
E
E
M
E
M
P
V
V
F
F
V
D
P
E
I
V
K
P
V
E
T
Q
G
I
K
T
L
T
L
S
Y
T
F
Y
P
R
E
P
SK---------------------------------------------------------
43
Fugue
64.02
21%
-91
- C3 -
4MFL
7
?
A:
[23-345]
MD
P
E
T
V
R
I
A
L
GLEERT
A
A
W
L
T
E
L
D
E
L
GPPAE
P
V
R
L
P
R
G
E
E
A
R
D
L
L
R
R
L
EVP
E
L
D
A
E
E
I
V
A
A
APDPDRD
P
A
L
W
W
L
L
E
R
T
H
H
A
I
V
R
H
MGDHRAKPRGGPPLPYEGG
A
A
A
R
Y
F
H
V
Y
V
F
L
A
T
V
P
A
-
V
R
R
F
H
A
E
-
R
G
I
---
P
D
E
V
----
G
W
E
T
L
T
-----
Q
--
L
G
E
L
V
A
I
-
H
R
R
K
Y
G
Q
G
G
M
N
M
----------------
Q
W
W
T
T
Y
H
--
L
R
G
I
L
Y
R
L
G
R
---------------------
L
Q
F
S
L
A
---------------
T
G
--
K
D
G
T
P
H
-
L
------
G
--
L
A
V
P
E
WGGP
L
L
P
K
A
Y
D
E
---
S
L
H
R
A
R
P
-----
F
---
F
-
D
-
R
--
H
F
P
E
H
G
A
R
V
A
W
G
S
S
W
M
L
D
P
Q
--
L
E
E
Y
L
T
E
D
S
N
I
I
Q
L
A
R
F
W
T
L
T
D
SAPEPGNADG
D
S
S
I
L
E
F
V
FRYNGQPLDELPQRS
S
L
E
R
A
V
I
A
H
L
K
A
G
R
H
W
H
M
R
T
G
F
V
K
L
P
40
Fugue
63.09
18%
-73
- C2 -
2QZQ
-
AIDA_DANRE
A:
[19-170]
--------------------------------------------------------------------------------------------------------------------G
S
L
L
P
-
R
L
P
S
E
P
G
M
T
L
L
---
T
L
T
I
----
E
K
I
G
L
K
D
A
G
Q
C
I
--
D
-
P
Y
I
T
V
-
S
V
K
D
L
N
G
I
D
L
N
P
V
Q
D
T
P
V
A
T
R
K
-
E
D
T
-
Y
I
H
F
S
V
D
V
--
E
I
Q
R
H
---------------------------------------------------
L
E
K
L
P
K
-
G
------
A
--
A
I
F
F
E
----
F
K
H
Y
K
P
K
K
---
R
F
T
S
T
K
C
-----
F
A
--
F
M
E
M
D
--
E
I
----
K
P
G
P
I
V
I
E
L
Y
K
K
P
---
T
D
F
K
R
K
K
L
N
L
L
T
K
K
P
L
Y
L
H
L
N
Q
T
L
H
K-------------------------------------------------------
45
Fugue
56.21
14%
-60
* C3 *
2HF6
-
COPZ1_HUMAN
A:
[1-149]
---------------------------------------------------------------------------------------------------------------------
M
E
A
L
-
I
L
E
P
S
L
Y
-
T
V
K
---
A
I
L
I
----
L
D
--------------------------
N
D
G
D
R
L
F
A
K
Y
Y
D
D
T
Y
P
-
S
V
K
E
Q
K
A
F
E
K
N
I
--
F
N
K
T
H
R
T
D
S
E
I
A
L
-----
L
E
G
L
T
V
V
Y
K
S
S
ID
L
Y
F
Y
V
I
---------------
G
S
--
S
Y
E
N
E
L
-
M
------
L
--
M
A
V
L
N
----
C
L
F
D
S
L
S
Q
---
M
L
R
K
N
V
E
-----------
K
-
R
--
A
L
L
E
N
M
E
G
L
F
L
A
V
D
E
I
V
D
G
G
V
I
L
E
S
D
P
Q
Q
V
V
H
R
V
A
L
R
------------------------------------------------------------------
16
PsiBlast_PDB
55.35
27%
-63
- C5 -
3T7Z
2
Y694_METJA
A:
[2-99]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
V
T
-
F
T
P
Y
G
A
F
G
V
K
D
N
K
E
V
S
G
L
E
D
I
E
-
Y
K
K
L
---
F
N
E
E
E
--
I
P
D
I
M
F
K
L
K
T
Q
P
N
-----
K
I
A
D
E
L
K
E
E
W
---
G
D
E
I
K
L
---------------
E
T
--
L
S
T
E
P
F
N
I
------
G
--
E
F
L
R
N
-----
N
L
F
K
V
G
K
E
L
G
Y
F
N
N
Y
D
E
-----
F
R
--
K
-
K
-
M
--
H
Y
W
S
T
E
L
T
K
K
V
I
K
S
Y
A
---------------------------------------------------------------------------------------
20
PsiBlast_PDB
55.15
29%
-38
- C4 -
4IAU
5
?
A:
[12-98]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
S
S
Q
D
F
T
S
E
Q
T
N
I
T
-
T
D
F
A
R
V
R
V
T
K
G
M
-------
W
I
F
Y
Q
Q
A
N
-----
Y
N
D
A
S
-
G
G
G
S
---
L
W
I
K
L
D
---------------
E
S
S
H
L
M
D
L
P
F
-
T
------
P
--
R
S
F
R
P
----
V
K
T
F
Q
V
G
A
---
T
L
Y
K
H
V
N
-----
F
G
--
G
-
K
-
E
--
L
D
L
P
N
S
N
P
R
I
D
I
G
G
V
S
S
A
L
I
S
Q
G
Q
W
R
L
Y
E
Q
Y
D
Y
A
G
P
S
T
R
R
G
P
G
V
-----------------------------------------------------------
30
HHSearch
52.86
26%
-81
- C4 -
2E6J
-
A:
[22-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
T
G
S
A
H
---
C
Y
E
A
I
L
---------------
Y
N
--
K
G
S
I
D
A
-
L
------------
F
N
----
M
T
P
P
T
S
A
-------
L
G
A
C
-----
F
V
--
F
-
S
-
P
K
E
G
I
I
E
P
S
G
V
Q
A
I
Q
I
S
F
S
S
I
I
L
G
N
F
E
E
E
F
L
V
N
V
N
G
S
P
E
P
V
K
L
T
I
R
G
-----------------------------------------------------------
44
Fugue
52.39
11%
-109
- C3 -
4YN9
2
?
A:
[7-159]
------------------------------------------------------------------------------------------------------------------------
R
-
T
S
I
E
Q
R
S
-
N
A
V
---
S
Q
V
L
----
L
G
I
F
S
Y
V
R
W
P
K
E
--
P
A
V
L
Q
L
C
-
V
V
G
P
T
E
Y
A
D
G
L
L
R
G
M
V
Q
A
N
G
R
--------
R
V
H
A
E
R
--
R
A
V
D
N
P
D
L
G
T
L
S
N
-----
V
I
Y
L
G
V
V
D
E
R
---
E
R
Q
Q
V
F
---------------
R
S
--
L
A
G
H
P
V
-
L
------
S
--
I
S
E
-------------------
R
G
T
E
C
SVGSM
F
C
--
L
-
N
-------
V
G
G
P
R
I
T
F
E
A
----------
N
L
D
S
I
A
R
S
G
V
R
V
H
P
S
V
L
K
L
A
R
R
Q
A
TP------------------------------------------------------
17
PsiBlast_PDB
52.03
30%
-83
- C6 -
1I1I
-
NEUL_RAT
P:
[387-447]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
H
V
W
N
K
S
---
V
S
L
Y
T
V
---------------
K
D
--
K
A
T
G
E
V
-
L
------
G
--
Q
F
Y
L
D
----
L
Y
P
-
R
E
G
K
---
Y
-
N
H
A
A
C
-----
F
G
--
L
-
Q
-
P
--
G
C
L
L
P
D
G
S
R
M
M
S
V
A
A
L
V
V
N
F
S
Q
P
V
A
G
R
P
S
L
L
R
H
D
E
V
R
T
Y
F
H
E
F
G
-----------------------------------------------------------
18
PsiBlast_PDB
52.00
30%
-79
- C6 -
2O3E
-
NEUL_RAT
A:
[387-447]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
H
V
W
N
K
S
---
V
S
L
Y
T
V
---------------
K
D
--
K
A
T
G
E
V
-
L
------
G
--
Q
F
Y
L
D
----
L
Y
P
-
R
E
G
K
---
Y
-
N
H
A
A
C
-----
F
G
--
L
-
Q
-
P
--
G
C
L
L
P
D
G
S
R
M
M
S
V
A
A
L
V
V
N
F
S
Q
P
V
A
G
R
P
S
L
L
R
H
D
E
V
E
T
Y
F
H
E
F
G
-----------------------------------------------------------
48
Fugue
51.46
19%
-67
- C1 -
2XQH
4
?
A:
[23-280]
----------------------------------------------------------------------------------------------------------SDAKASGEF
S
V
A
V
G
N
G
A
R
A
T
E
K
A
-
S
T
A
V
G
S
W
A
A
A
DGKQ
S
T
A
L
G
V
G
T
Y
A
Y
A
NA
S
T
A
L
G
S
V
A
F
V
D
N
T
A
T
Y
G
T
A
A
G
N
R
A
K
V
D
K
D
A
-
T
E
G
T
A
L
G
A
K
A
T
V
TN
K
N
S
V
A
L
G
A
N
S
V
T
T
R
DNEV
Y
I
G
Y
K
T
G
T
E
S
---
D
K
T
Y
G
T
R
V
L
G
GLSDGTRNSDA
A
T
--
V
G
Q
L
N
R
-
K
------
V
--
G
G
V
Y
D
----
D
V
K
A
R
I
T
V
---
E
S
E
K
Q
K
K
-----
Y
---
T
-
D
-
Q
--
K
T
S
E
V
N
E
K
V
E
A
R
T
T
V
G
V
D
S
D
G
K
L
T
R
A
E
G
A
T
K
T
I
A
V
N
D
G
L
V
A
L
S
G
R
T
D
R
I
D
Y
A
V
G
A
I
D
G
R
V
T
R
N
T
Q
S
I
E
K
N
S
K
A
I
A
A
N
T
RT-----------------------
33
HHSearch
51.08
19%
-65
- C4 -
1Z9L
-
VAPA_RAT
A:
[22-94]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
D
V
V
---
T
T
N
L
K
L
---------------
Q
N
--
P
S
D
R
K
V
-
C
F
K
V
K
T
T
A
--
P
R
R
Y
C
----
V
R
P
N
S
-----------------------------
G
V
I
D
P
G
S
I
V
T
V
S
V
-
L
Q
P
F
D
Y
---
D
P
N
E
K
S
K
H
K
F
M
V
Q
T
I
F
A
P
P
N
I
-----------------------------------------------------------
36
HHSearch
50.63
18%
-77
- C4 -
2CRI
-
VAPA_MOUSE
A:
[29-101]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
D
V
V
---
T
T
N
L
K
L
---------------
Q
N
--
P
S
D
R
K
V
-
C
------------
F
K
----
V
K
T
T
A
P
R
R
---
Y
C
V
R
P
N
--------------
S
--
G
I
I
D
P
G
S
I
V
T
V
S
V
M
L
Q
P
F
D
Y
---
D
P
N
E
K
S
K
H
K
F
M
V
Q
T
I
F
A
P
P
N
I
-----------------------------------------------------------
19
PsiBlast_PDB
50.39
30%
-79
- C6 -
4FXY
-
NEUL_RAT
P:
[399-459]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
H
V
W
N
K
S
---
V
S
L
Y
T
V
---------------
K
D
--
K
A
T
G
E
V
-
L
------
G
--
Q
F
Y
L
D
----
L
Y
P
-
R
E
G
K
---
Y
-
N
H
A
A
C
-----
F
G
--
L
-
Q
-
P
--
G
C
L
L
P
D
G
S
R
M
M
S
V
A
A
L
V
V
N
F
S
Q
P
V
A
G
R
P
S
L
L
R
H
D
E
V
R
T
Y
F
H
E
F
G
-----------------------------------------------------------
27
HHSearch
47.74
11%
-98
- C4 -
2QSV
-
?
A:
[15-70]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
P
E
D
E
G
---
V
V
R
L
V
V
---------------
N
N
--
T
D
E
S
D
L
-
Q
------
V
--
A
--------
V
V
S
--
L
P
S
---
F
V
S
-
L
--------
D
--
D
-
R
-
A
--
F
R
L
Q
A
R
E
P
R
E
L
N
L
S
L
A
V
P
R
N
M
P
P
G
M
K
D
E
P
L
V
L
E
V
T
S
P
E
T
G
K
K
A
V
-----------------------------------------------------------
28
HHSearch
45.62
12%
-88
- C4 -
3QIS
-
A:
[41-107]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
K
F
R
Q
L
Q
---
K
E
K
F
Q
I
---------------
S
N
--
N
G
Q
V
P
C
-
H
------
F
--
S
F
I
P
K
----
L
N
---
D
S
Q
---
Y
C
K
--
P
W
-----
L
R
AE
P
-
F
-
E
--
G
Y
L
E
P
N
E
T
V
D
I
S
L
D
V
Y
V
S
K
D
S
V
T
I
L
N
S
G
E
D
K
I
E
D
I
L
V
L
H
L
D
R
G
K
-----------------------------------------------------------
35
HHSearch
45.02
17%
-89
- C4 -
2KUT
-
?
A:
[12-71]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
E
G
E
E
I
---
T
V
S
A
R
V
---------------
T
N
--
R
G
A
A
E
A
-
H
------
N
V
P
V
A
V
Y
L
----
G
N
P
A
Q
G
G
V
---
E
I
G
R
D
T
I
----------------
S
R
I
P
V
G
G
T
G
L
A
R
V
Q
W
K
A
T
R
K
L
A
G
R
A
A
N
P
G
V
P
V
Y
A
V
V
D
P
D
N
R
V
A
E
-----------------------------------------------------------