@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0690: (2015-12-03 )
MALAISFFITLFIMLSILTQSIEFFKKVSISEFLFCLKWGHSVLTINEEKVRCFGITPLLVGTLVITIVAMLVAVPLGLFSAIYISEYASEKVRYIVNTTLQVLSAIPTVVYGYFSVVFLSSFVKQIASFFGLNIHSESALVAGLSIGIMILPFIISLLEDAIRSVPKSLRYGFMALGATPAETIWHITIPYAMPTILSAILLSISRVIGETMIVLMAVGINSNLTFNPLNSVTTITVQIATLLTGDQDFNSIQTLAAYVLSLVLFIITWLLNAFALFIIKRN
Atome Classification :
(20 SA)
.........10........20........30........40........50..--......60........70........80.....---.----..90-----.........100.......110.......120.---...--------...130..--...---...140.......150----........160.......170.......180.......190..----.....200.......210.......220...-.--...---230.......240.......250.......260.......270.......280.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
L
A
I
S
F
F
I
T
L
F
I
M
L
S
I
L
T
Q
S
I
E
F
F
K
KV
S
I
S
E
F
L
F
C
L
KWGH
S
V
L
T
INEE
K
V
R
C
--FG
I
T
P
L
L
V
G
T
L
V
I
T
I
V
A
M
L
V
A
V
P
L
G
L
F
S
A
I
Y
I
S
---
E
----
Y
A
S
------
E
K
V
R
Y
I
V
N
T
T
L
Q
V
L
S
A
I
P
T
V
V
Y
G
Y
F
S
V
V
F
L
S
S
F
---
V
K
Q
--------
I
A
S
F
-FGL--NIH---SE
S
A
L
V
A
G
L
S
I
G
I
M
I
-----
L
P
F
I
I
S
L
L
E
D
A
I
R
S
V
P
K
S
L
R
Y
G
F
M
ALGA
T
P
A
E
T
I
W
H
I
TI
P
Y
A
M
----
P
T
I
L
S
A
I
L
L
S
I
S
R
V
I
G
E
T
M
I
V
L
M
A
VGINSN
L
-
T
--FNP---LNS
V
T
T
I
T
V
Q
I
A
T
L
LTGDQ
D
F
N
S
I
Q
T
L
A
A
Y
V
L
S
L
V
L
F
I
I
T
W
L
L
N
A
F
A
L
F
I
I
KRN
24
HHSearch
82.12
18%
-177
* C2 *
3TUI
-
METI_ECOLI
A:
[9-213]
---------------------------------------------------------
L
V
R
G
V
W
E
T
L
A
M
T
F
V
S
G
F
F
G
F
V
I
G
L
P
V
G
V
L
L
Y
---
V
----
T
R
P
GQIIAN
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
I
P
F
I
I
L
L
V
W
M
I
P
F
T
R
V
I
-------------------
V
G
-----
T
---
S
I
G
L
Q
A
A
I
V
P
L
T
V
G
A
-----
A
P
F
I
A
R
M
V
E
N
A
L
L
E
I
P
T
G
L
I
E
A
S
R
A
M
G
A
T
P
M
Q
I
V
R
K
V
L
L
P
E
A
L
----
P
G
L
V
N
A
A
T
I
T
L
I
T
L
V
G
Y
S
A
M
G
G
A
V
G
-------------------
A
G
G
L
G
Q
I
G
Y
Q
Y
G
Y
I
G
-----
Y
N
A
T
V
M
N
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
A
V
31
Fugue
79.75
17%
-148
- C2 -
2ONK
-
WTPB_ARCFU
C:
[24-275]
M
R
L
L
F
S
A
L
L
A
L
L
S
S
I
I
L
L
F
V
L
L
P
V
A
A
T
V
T
L
Q
L
F
---------
N
F
D
E
F
L
K
A
A
S
D
--
P
A
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
---
R
----
K
-
S
------
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
----
S
G
L
--------
I
G
S
F
-
S
P
L
--
K
F
----
V
D
A
L
P
G
I
V
V
A
M
L
F
V
S
-----
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
----
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
F
G
A
V
V
V
I
A
Y
---------------
Y
P
M
I
A
P
T
L
I
Y
E
R
Y
L
S
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
F
V
A
L
R
I
I
V
G
----------
18
PsiBlast_PDB
78.94
20%
-147
- C2 -
3PUW
3
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
20
PsiBlast_PDB
78.68
20%
-150
- C2 -
3RLF
2
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
17
PsiBlast_PDB
78.56
20%
-149
- C2 -
3PUV
3
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
15
PsiBlast_PDB
78.44
20%
-150
- C2 -
3PUZ
2
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
19
PsiBlast_PDB
78.38
20%
-145
- C2 -
3PUX
3
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
16
PsiBlast_PDB
78.36
20%
-148
- C2 -
3PV0
2
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
N
--------
13
PsiBlast_PDB
78.13
20%
-153
- C2 -
2R6G
1
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
V
---------
14
PsiBlast_PDB
78.05
20%
-149
- C2 -
3PUY
2
MALF_ECOLI
F:
[280-498]
------------------------------------------------------------
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
W--
E
----
A
L
R
------
G
K
A
V
Y
------
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
---
F
N
Q
SFGEINMM
L
S
A
L
-
F
G
V
--
K
P
A
---
W
F
S
D
P
T
T
A
R
T
M
L
I
I
V
NTWLG
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
KPLT
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
---
L
I
Q
L
L
T
N
G
G
P
D
R
L
G
T
--
T
T
P
AGY
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
G
G
Q
D
F
G
----
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
----------
21
HHSearch
75.78
12%
-137
- C2 -
3RLF
2
MALF_ECOLI
F:
[258-503]
--------------------------------------
T
T
G
W
K
N
F
T
R
V
F
T
D
E
G
IQ
K
P
F
L
A
I
F
V
W
T
V
V
F
S
L
I
T
V
F
L
T
V
A
V
G
M
V
L
A
C
L
V
Q
---
W
----
E
A
-------
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
V
P
S
F
I
S
I
L
I
F
K
G
L
F
N
Q
S
FGE
I
N
M
--------
M
L
S
A
L
F
G
V
KP
A
W
F
SDP
T
T
A
R
T
M
L
I
I
V
N
T
W
L
G
-----
Y
P
Y
M
M
I
L
C
M
G
L
L
K
A
I
P
D
D
L
Y
E
A
S
A
M
D
G
A
G
P
F
Q
N
F
F
K
I
T
L
P
L
L
I
----
K
P
L
T
P
L
M
I
A
S
F
A
F
N
F
N
N
F
V
L
I
Q
L
L
T
N
G
G
P
D
R
-
L
GT
T
T
P
---
A
G
Y
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
G
G
--
G
G
Q
D
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
---------
23
HHSearch
75.54
17%
-164
- C2 -
2ONK
-
WTPB_ARCFU
C:
[70-275]
---------------------------------------------------------
V
W
K
V
V
L
T
T
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
G
T
P
L
A
Y
I
L
A
---
R
----
K
S
-------
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
I
P
H
T
V
A
G
I
A
L
L
V
V
F
G
S
S
GL-
I
G
S
--------
F
S
----
P
L
--
K
-
F
---
V
D
A
L
P
G
I
V
V
A
M
L
F
V
S
-----
V
P
I
Y
I
N
Q
A
K
E
G
F
A
S
V
D
V
R
L
E
H
V
A
R
T
L
G
S
S
P
L
R
V
F
F
T
V
S
L
P
L
S
V
----
R
H
I
V
A
G
A
I
M
S
W
A
R
G
I
S
E
F
G
A
V
V
V
I
A
Y
Y
-----------------
P
M
I
A
P
T
L
I
Y
E
R
Y
L
S
------
E
G
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
F
V
A
L
R
I
I
V
G
--
32
Fugue
74.06
15%
-160
- C2 -
4YMU
2
?
C:
[1-214]
---------------------------------------------
M
T
V
D
F
L
S
M
--
V
K
Y
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
---
L
----
M
K
M
SSI---
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
----------
L
L
V
Q
L
---
L
L
I
--------
Y
N
G
L
-
M
Q
F
--
G
M
N
---
I
P
A
F
T
A
G
V
S
A
L
A
I
N
S
-----
S
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
-------------------
G
F
A
D
L
T
R
Q
A
D
I
I
Q
S
V
T
Y
R
----
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
6
PsiBlast_PDB
73.47
22%
-158
- C2 -
4YMS
-
?
D:
[12-163]
----------------------------------------------------------
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
LMK
M
----
S
S
I
------
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
L
L
V
----
Q
L
L
L
I
Y
N
G
---
L
M
Q
-------------
F
G
M
--
N
I
P
---
A
F
T
A
G
V
S
A
L
A
I
N
S
S
-------
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
G
F
A
D
L
T
R
-
Q
--
A
D
I
---
I
Q
S
V
T
Y
R
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
R
----------------
8
PsiBlast_PDB
73.02
22%
-152
- C2 -
4YMU
2
?
D:
[12-163]
----------------------------------------------------------
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
LMK
M
----
S
S
I
------
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
L
L
V
----
Q
L
L
L
I
Y
N
G
---
L
M
Q
-------------
F
G
M
--
N
I
P
---
A
F
T
A
G
V
S
A
L
A
I
N
S
S
-------
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
G
F
A
D
L
T
R
-
Q
--
A
D
I
---
I
Q
S
V
T
Y
R
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
R
----------------
9
PsiBlast_PDB
73.00
22%
-151
- C2 -
4YMV
-
?
D:
[12-163]
----------------------------------------------------------
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
LMK
M
----
S
S
I
------
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
L
L
V
----
Q
L
L
L
I
Y
N
G
---
L
M
Q
-------------
F
G
M
--
N
I
P
---
A
F
T
A
G
V
S
A
L
A
I
N
S
S
-------
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
G
F
A
D
L
T
R
-
Q
--
A
D
I
---
I
Q
S
V
T
Y
R
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
R
----------------
10
PsiBlast_PDB
72.78
22%
-153
- C2 -
4YMW
2
?
D:
[12-163]
----------------------------------------------------------
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
LMK
M
----
S
S
I
------
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
L
L
V
----
Q
L
L
L
I
Y
N
G
---
L
M
Q
-------------
F
G
M
--
N
I
P
---
A
F
T
A
G
V
S
A
L
A
I
N
S
S
-------
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
G
F
A
D
L
T
R
-
Q
--
A
D
I
---
I
Q
S
V
T
Y
R
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
R
----------------
22
HHSearch
72.42
14%
-159
- C2 -
3D31
-
?
C:
[80-283]
---------------------------------------------------------
V
I
S
S
I
F
L
S
L
Y
A
G
F
L
A
T
L
L
A
L
L
L
G
A
P
T
G
Y
I
L
A
---
R
----
F
D
-------
F
P
G
K
R
L
V
E
S
I
I
D
V
P
V
V
V
P
H
T
V
A
G
I
A
L
L
T
V
F
G
S
R
GL-
I
G
E
--------
P
L
E
S
-
Y
----
I
Q
F
---
R
D
A
L
P
G
I
V
V
A
M
L
F
V
S
-----
M
P
Y
L
A
N
S
A
R
E
G
F
K
S
V
D
P
R
L
E
N
A
A
R
S
L
G
A
P
L
W
K
A
F
F
F
V
T
L
P
L
S
A
----
R
Y
L
L
I
G
S
V
M
T
W
A
R
A
I
S
E
F
G
A
V
V
I
L
A
Y
Y
-----------------
P
M
V
G
P
T
L
I
Y
D
R
F
I
S
------
Y
G
L
S
A
S
R
P
I
A
V
L
L
I
L
V
T
L
S
I
F
L
V
I
R
------
7
PsiBlast_PDB
72.38
22%
-149
- C2 -
4YMT
2
?
C:
[12-163]
----------------------------------------------------------
T
P
L
F
I
S
G
L
I
M
T
L
K
L
T
F
L
A
V
T
I
G
V
L
M
G
L
F
I
A
LMK
M
----
S
S
I
------
K
P
I
K
L
V
A
S
S
Y
I
E
V
I
R
G
T
P
L
L
V
----
Q
L
L
L
I
Y
N
G
---
L
M
Q
-------------
F
G
M
--
N
I
P
---
A
F
T
A
G
V
S
A
L
A
I
N
S
S
-------
A
Y
V
A
E
I
I
R
A
G
I
Q
A
V
D
P
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
A
M
R
Y
V
I
I
P
Q
A
I
----
K
N
I
L
P
A
L
G
N
E
F
I
V
M
L
K
E
S
A
I
V
S
V
I
G
F
A
D
L
T
R
-
Q
--
A
D
I
---
I
Q
S
V
T
Y
R
Y
F
E
P
Y
I
I
I
A
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
E
R
R
L
R
----------------
2
PsiBlast_PDB
71.55
23%
-175
- C2 -
3TUI
-
METI_ECOLI
A:
[12-159]
--------------------------------------------------------
G
V
W
E
T
L
A
M
T
F
V
S
G
F
F
G
F
V
I
G
L
P
V
G
V
L
--
L
Y
V
T
---
R
PGQI
I
A
N
------
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
I
P
F
I
I
L
----
L
V
W
M
I
P
F
---
T
R
V
--------
I
V
----
G
T
--
S
I
G
---
L
Q
A
A
I
V
P
-
L
T
V
G
A
A
-------
P
F
I
A
R
M
V
E
N
A
L
L
E
I
P
T
G
L
I
E
A
S
R
A
M
G
A
T
P
M
Q
I
V
R
K
V
L
L
P
E
A
L
----
P
G
L
V
N
A
A
T
I
T
L
I
T
L
V
G
Y
S
A
M
G
G
A
V
G
A
G
G
L
G
Q
-
I
--
G
Y
Q
---
Y
G
Y
I
G
Y
N
A
T
V
M
N
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
A
V
T
R
----------------