@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0260: (2016-03-13 )
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELIGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKSENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
Atome Classification :
(20 SA)
----------------------------------.........10........--20........30........40........50.---.......60........70..----------..--....80......-..90.-----....---...100...-....110........---120....---...130.......140-------------.--------------------...-----....150-........--160.......170......---.180.......190-------.........200...--....210.......220.......230....--....240....-...250-------.......260.......270.......280.....------------------..290.---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------MS
I
V
A
L
L
I
G
L
G
P
L
I
G
W
G
F
F
--
P
T
V
A
S
KFGG
K
P
V
H
Q
I
I
G
A
T
V
G
T
L
I
F
A
I
I
L
A
V
V
T---SSGFP
T
G
T
N
L
L
F
A
L
L
SGAGWG----------F
G
--
Q
I
I
T
F
K
A
F
E
L
IG-SSRAM-----
P
V
T
T
---
A
F
Q
L
L
G
A
S
L
-
W
G
V
F
AL-GNWPGIG
H
---
K
I
I
G
F
T
A
---
L
V
V
I
L
IGAR
M
T
V
W
S
E
--------------
R
--------------------KEA-----S
N
A
K
N
L
--
R
R
A
V
V
L
L
L--IGEF
G
Y
W
L
YSAAPQATSI
D
---
G
L
T
A
F
L
P
Q
A
M
G
M
---------
V
I
V
A
V
I
Y
G
F
MNMKSE--NPFRN
K
I
T
W
L
Q
I
I
S
G
F
F
F
A
F
G
A
L
T
Y
-
L
ISAQ--PNMNGLA
T
G
F
I
-LSQ
T
S
V
-------
V
L
A
T
L
T
G
I
Y
F
L
K
QHKTS
K
E
M
V
I
T
I
I
G
L
V
L
I
L
V
A
A
S
------------------
V
T
V
F
IK---
16
Fugue
83.30
17%
-151
- C1 -
3VSE
1
?
A:
[1-390]
M
K
I
A
T
L
N
K
GKE
T
K
Y
F
N
GYPLIEEEDIYSQDHLKE
G
D
I
F
Q
I
V
T
D
K
S
Q
Y
V
A
T
A
Y
V
--
G
R
Q
-
H
K
G
L
G
W
V
L
T
Y
D
K
A
Q
E
I
N
T
A
F
F
V
K
L
F
N
T
A
L
A
E
R
D
Y
Y
F
N
I
D
G
T
N
A
F
R
L
F
N
A
E
G
D
G
----------
V
G
G
L
T
I
D
N
Y
D
G
H
L
L
I
Q
W
Y
S
K
G
I
Y
K
F
K
Y
A
I
L
E
---
A
V
R
K
V
-
F
D
Y
-
K
S
I
Y
E
K
-
V
R
F
K
D
S
E
Y
SGG
F
V
E
G
D
A
P
EFP
I
V
I
E
E
N
F
T
F
Y
N
V
D
L
E
DGLMTGIFLDQ
K
E
V
R
--------------------
K
K
L
-----
R
G
Q
Y
A
K
--
E
R
H
V
L
N
L
F
SY
T
G
A
F
S
V
I
A
A
S
E
A
S
S
T
T
S
V
D
LAN
R
S
R
S
L
T
E
E
N
F
G
L
N
AIDPKS
Q
Y
I
Y
V
M
D
T
F
D
F
Y
K
Y
A
A
R
--
H
G
H
S
Y
D
T
I
V
I
D
P
P
S
--
F
A
R
N
K
K
R
T
F
S
V
Q
K
D
Y
--
D
K
L
I
N
G
A
L
N
I
L
-
S
S
E
G
T
L
-------
L
L
C
T
N
A
S
V
Y
P
L
K
Q
F
K
N
T
I
K
K
T
L
E
E
S
G
V
D
Y
E
L
T
E
V
M
G
L
PKDFKTHPHYKPSKY
L
K
A
V
F
V
N
I
R
H
23
Fugue
79.98
17%
-162
* C2 *
3K9G
12
?
A:
[26-267]
---------------------------------K
P
K
I
I
T
I
------------------
A
S
I
K
G
G
------
V
G
K
S
T
S
A
I
I
L
A
T
L
L
S
-----------
K
N
N
K
V
L
L
I
D
M
D
T
Q
A
----------------
S
I
T
S
Y
F
Y
E
K
I
E
K
-
L
G
I
N
F
-----
T
K
F
N
---
I
Y
E
I
L
K
E
N
------------
V
D
I
D
S
---
T
I
I
N
V
D
N
N--
L
D
L
I
P
S
Y
L
T
L
H
N
F
S
E
--------------
D
--------------------
K
I
E
-----
H
K
D
F
L
L
--
K
T
S
L
G
T
L
Y
---
Y
K
Y
D
Y
I
V
I
D
T
N
P
---
S
L
D
---
V
T
L
K
N
A
L
L
C
S
D
Y
---------
V
I
I
P
M
T
A
E
K
W
A
V
E
S
L
--
D
L
F
N
F
F
V
R
K
L
---
N
L
F
L
P
I
F
L
I
I
T
R
-
F
K
K
N
R
--
T
H
K
-------------
T
L
-------
F
E
I
L
K
T
K
D
R
F
L
G
T
I
S
E
N
K
D
Y
I
K
E
Y
E
N
I
L
E
I
F
L
K
K
I
---------------------------
2
PsiBlast_PDB
65.49
29%
-153
- C1 -
2HIM
5
ASPG1_ECOLI
A:
[242-342]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
D
---
V
V
R
N
F
L
R
Q
P
V
K
A
---------
L
I
L
R
S
-
Y
G
V
G
N
A
P
Q
N
--
K
A
F
---
L
Q
E
L
Q
E
A
S
D
R
G
I
V
V
V
N
L
T
Q
-
C
M
S
G
K
--
V
N
M
G
-----
N
A
-
L
A
H
A
G
V
IGGADMT
V
E
A
T
L
T
K
L
H
Y
L
L
S
Q
E
L
D
T
E
T
I
-----------------------------------------
24
Fugue
64.14
16%
-119
- C2 -
1HV9
1
GLMU_ECOLI
A:
[4-251]
--------------------------------N
A
M
S
V
V
I
L
A
A
G
K
G
T
R
M
Y
S
---DL
P
K
V
L
H
T
L
A
G
K
A
M
V
Q
H
V
I
D
A
A
N
E
L
G
A
A
H
V
H
L
V
Y
G
---
H
-
G
---
G
D
L
L
K
Q
A
L
K
D
D
------------------
N
L
N
W
V
L
Q
A
E
Q
L
G
-
T
G
H
A
M
-----
Q
Q
-----
A
A
P
F
F
A
D
-
D
-
E
D
I
L
M
L
Y
G
D
V
P
L
I
S
V
---
E
T
L
Q
R
L
R
---
D
A
K
P
--
Q
G
G
I
G
L
L
T
V
--------------
K
L
DDPTG
Y
G
R
I
T
R
E
NGKVT
G
I
V
E
H
-----
K
D
A
T
D
E
--
Q
R
Q
I
Q
E
I
N
--
T
G
I
L
I
A
N
G
A
D
M
K
R
W
L
A
K
L
T
---
N
N
N
A
Q
G
E
Y
Y
I
T
D
---------
I
I
A
L
A
Y
Q
E
G
R
E
I
V
A
V
H
P
Q
R
L
S
E
V
---
E
G
V
N
N
--
R
L
Q
L
S
R
L
E
R
-
V
Y
Q
S
E
--
Q
A
E
K
L
L
L
A
G
------------------------------------------------------------------------------
3
PsiBlast_PDB
63.07
29%
-155
- C1 -
2P2D
1
ASPG1_ECOLI
A:
[242-342]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
D
---
V
V
R
N
F
L
R
Q
P
V
K
A
---------
L
I
L
R
S
-
Y
G
V
G
N
A
P
Q
N
--
K
A
F
---
L
Q
E
L
Q
E
A
S
D
R
G
I
V
V
V
N
L
T
Q
-
C
M
S
G
K
--
V
N
M
------
N
A
-
L
A
H
A
G
V
IGGADMT
V
E
A
T
L
T
K
L
H
Y
L
L
S
Q
E
L
D
T
E
T
I
-----------------------------------------
4
PsiBlast_PDB
61.05
29%
-162
- C1 -
2P2N
7
ASPG1_ECOLI
A:
[242-342]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
D
---
V
V
R
N
F
L
R
Q
P
V
K
A
---------
L
I
L
R
S
-
Y
G
V
G
N
A
P
Q
N
--
K
A
F
---
L
Q
E
L
Q
E
A
S
D
R
G
I
V
V
V
N
L
T
Q
-
C
M
S
G
K
--
V
--------
N
A
-
L
A
H
A
G
V
IGGADMT
V
E
A
T
L
T
K
L
H
Y
L
L
S
Q
E
L
D
T
E
T
I
-----------------------------------------
7
HHSearch
55.18
14%
-125
- C- -
3B5D
1
EMRE_ECOLI
A:
[34-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
-
A
Q
T
L
A
--
Y
--
I
P
T
G
I
A
Y
A
I
W
S
G
V
G
I
-------
V
L
I
S
L
L
S
W
G
F
F
G
Q
R
L
D
L
P
A
I
----
I
G
M
M
L
I
C
A
G
V
L
------------------
I
I
N
L
L
----
17
Fugue
47.60
19%
-111
- C1 -
1QGT
-
?
A:
[1-142]
-----------------------------------------------------------------------------------------------------------------------------------------------------
M
D
I
D
---
P
Y
K
E
F
G
A
T
----
V
E
L
L
-
S
F
L
P
---------
S
D
F
F
P
---
S
V
R
D
L
L
D
T
A
S
A
L
Y
R
E
--------------
A
--------------------
L
E
S
PEHCS
P
H
H
T
A
L
--
R
Q
A
I
L
C
W
G
E
-
L
M
T
L
A
T
W
V
G
N
N
L
E
D
P
A
S
R
D
---
L
V
V
N
Y
V
N
T
N
M
G
L
---------
K
I
R
Q
L
L
W
F
H
I
S
C
L
T
F
--
G
--------
R
E
T
V
L
E
Y
L
V
S
F
G
V
W
I
R
-
T
P
P
A
Y
RP
P
N
A
P
I
L
S
T
-------------------------------------------------------------------------------
5
PsiBlast_PDB
40.37
32%
-97
- C1 -
3HUR
2
?
A:
[30-90]
------------------------------------------------------------------------------------------------
T
K
A
K
K
V
Y
A
V
L
K
A
D
G
Y
G
----------
L
G
--
A
I
P
L
A
K
A
F
Q
E
T
A
-
S
A
D
A
L
-----
I
V
S
N
L
D
E
A
L
E
L
R
Q
A
D
L
T
L
P
I
W
V
L
-
G
A
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
40.29
8%
-93
- C2 -
2XZ8
3
PGPLF_DROME
A:
[7-141]
------------------------------------------------------------------------------------------------------
V
K
I
V
T
R
P
Y
W
L
AQPPI
V
P
L
T
P
L
K
--
L
P
I
E
S
V
R
F
V
A
T
N
-
T
P
S
C
F
-----
T
Q
A
E
---
C
T
F
R
V
R
L
L
Q
-
N
W
H
I
E
S
-
N
G
Y
K
D
I
N
Y
---
N
------------
F
V
A
A
G
D
E
N
I
Y
E
A
--------------
R
--------------------
G
W
D
-----
H
S
C
E
P
P
KD
A
D
E
L
V
V
A
F
--
I
G
----------
P
S
S
S
N
K
K
---
I
A
L
E
L
I
K
Q
G
I
K
L
---------
G
H
I
S
K
N
Y
S
L
I
D
D
L
E
K
--------------------------------------------------------------------------------------------------------------------------
9
HHSearch
35.37
12%
-138
- C- -
3B5D
1
EMRE_ECOLI
A:
[29-105]
---------------------------------------------------------------------------------------------------
R
L
W
P
S
V
G
T
I
I
C
Y
C
----------
A
S
--
F
W
L
L
A
Q
T
L
A
Y
I
P
-
T
G
I
A
Y
-----
A
I
W
S
---
G
V
G
I
V
L
I
S
L
-
L
S
W
G
F
F
-
G
Q
R
L
D
L
P
A
---
I
----
I
G
---
M
M
L
I
C
A
G
V
L
I
I
N
L
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
34.54
42%
35
- C1 -
4IVF
1
?
A:
[63-96]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
P
N
F
K
G
V
D
G
G
L
V
-
L
S
Q
T
G
A
-------
I
L
Q
Y
L
A
D
T
Y
-
D
K
E
H
K
F
S
---------------------------------------------
10
HHSearch
28.37
12%
156
- C1 -
2JO1
-
PLM_HUMAN
A:
[21-37]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
I
A
G
I
L
F
I
L
G
I
L
------------------
I
V
L
S
-----
22
Fugue
26.73
25%
76
- C1 -
2LX0
-
?
A:
[1-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
H
-----
T
I
W
E
V
I
--
A
G
L
V
A
L
L
T
--
F
L
A
F
G
F
W
L
F
K
Y
L
Q
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
25.02
17%
187
- C1 -
2ZXE
-
?
G:
[24-41]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
V
A
A
V
L
C
V
I
G
I
I
------------------
I
L
L
A
G
----
14
HHSearch
24.72
17%
182
- C1 -
2JP3
-
FXYD4_RAT
A:
[22-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
F
G
G
L
L
C
I
A
G
I
A
------------------
L
A
L
S
G
----
6
HHSearch
22.85
14%
-61
- C1 -
2I68
-
EMRE_ECOLI
A:
[34-104]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
-
A
Q
T
L
A
---------
I
A
Y
A
I
W
S
G
V
G
I
-------
V
L
I
S
L
L
S
W
G
F
F
G
------
A
I
----
I
G
M
M
L
I
C
A
G
V
L
------------------
I
I
N
L
L
----
19
Fugue
14.20
21%
325
* C1 *
2YKA
-
B:
[1-23]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
L
G
S
S
C
K
T
S
W
A
D
--------------
R
--------------------
V
R
E
-----
A
A
A
Q
R
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
12.69
21%
328
- C1 -
4XGC
-
F:
[38-56]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
Y
E
I
W
K
A
--------------
R
--------------------
M
L
A
-----
K
A
Q
A
K
L
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
10.47
13%
362
- C1 -
2HAC
-
CD3Z_HUMAN
A:
[12-27]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
V
I
L
T
A
L
F
L
R
V
K
F
S
R
---------------------------------------------