@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0273: (2016-03-14 )
MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTLFNKDSKEVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESDKSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------.........10......--.-.20........30..-------......40---.---..--......50........60.....-------...70..-.......80........90..-------......100.------......----110--------------....---....120-----....---..---.---130-----..-----.-------...----..140.......150------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------MLM
N
S
V
I
A
L
T
F
L
T
ASSN--N-G
G
L
N
I
D
V
Q
Q
E
E
E
K
R
I-------NN
D
L
N
Q
Y
----
D
---
T
T
--LFNK
D
S
K
E
V
N
D
A
I
A
K
Q
K
K
E
R
Q
Q
Q
-------
I
K
N
D
-
M
F
-
Q
NQASHSTR
L
N
E
T
K
K
V
L
FSKS-------NLEKTSESDK------SPYIQN----KQ---------------EKK
I
---
F
P
Y
I
L
M
S
-----
V
G
A
F
---
L
T
---
L
---
G
F
------
V
I
-----
F
-------
S
IH----KGRRTKNESARKSNI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
76.19
15%
44
- C8 -
1Q8C
11
Y027_MYCGE
A:
[12-151]
--------------------------------------------------------------------------------------------------LT
R
T
Q
R
R
I
A
V
V
E
F
I
F
S
L
----------
L
F
F
L
P
K
E
A
E
V
I
-------
Q
A
D
F
L
E
Y
----
D
---
T
K
ER
Q
L
N
E
W
Q
K
L
I
V
K
A
F
S
E
N
I
F
S
F
Q
K
K
-------
I
E
E
Q
-
Q
L
-
K
N
Q
L
E
I
Q
T
K
I
D
L
L
T
T
A
V
V
L
C
A
-------
L
S
E
Q
K
A
H
N
T
D
------
K
P
L
L
I
S
----
E
A
---------------
L
L
I
M
---
D
H
Y
------------------------------------------------
S
Q
G
----
A
E
K
K
Q
T
H
A
L
L
D
K
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
71.87
32%
76
- C8 -
4D7R
-
?
A:
[148-209]
---------------------------------------------------------------------------------------------------------------------------
L
N
I
D
I
N
S
K
D
A
A
Y
I
-------
L
----
A
Y
----
Q
---
T
I
--
M
L
N
T
D
L
H
--
N
P
S
I
A
K
S
K
K
M
T
F
E
Q
-------
L
K
N
N
-
L
K
-
G
T
N
E
S
K
N
F
N
D
N
F
L
K
K
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
70.91
13%
-4
- C7 -
1FLC
2
?
B:
[4-165]
-----------------------------------------------------------------------------------------------------
I
D
D
L
I
I
G
V
L
F
V
A
I
V
E
T
--
G
I
G
G
Y
L
L
G
S
R
K
E
S
G
G
G
V
-------
T
K
E
S
A
E
K
----
G
---
F
E
--
K
I
G
N
D
I
Q
I
L
K
S
S
I
N
I
A
I
E
K
L
N
D
R
-------
I
S
H
D
-
E
Q
-
A
I
R
D
L
T
L
E
I
E
N
A
R
S
E
A
L
L
G
E
L
-------
G
I
I
R
A
L
L
V
G
N
------
I
S
I
G
L
Q
----
E
S
---------------
L
W
E
L
---
A
S
E
I
T
N
R
-----
A
G
D
L
AVE
V
S
---
P
---
G
C
------
W
I
-----
I
D
NNICD
Q
S
C
Q
----
N
F
I
F
K
F
N
E
T
A
P
V
P
T
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
70.05
25%
-48
- C5 -
3JX8
5
?
A:
[12-76]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
P
E
T
R
E
I
K
I
S
D
Y
D
E
I
T
F
V
G
S
-------
A
D
F
E
Y
E
Q
S
D
K
------
A
P
Y
L
S
V
----
T
I
---------------
D
E
N
L
---
F
D
Y
L
V
T
E
-----
V
E
G
G
----
T
---
L
---
K
I
------
Y
P
-----
K
-------
S
I
K
----
K
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.57
23%
58
- C9 -
3R24
1
R1AB_CVHSA (first)
A:
[142-197]
---------------------------------------------------------------------------------------------------------------------------------------
V
-------
D
S
D
L
N
D
F
------------
V
S
D
A
D
S
T
L
I
G
D
C
A
T
V
H
T
A
N
K
W
D
L
-------
I
I
S
D
-
M
Y
-
D
P
R
T
K
H
V
T
K
E
N
D
S
K
E
G
F
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
64.89
33%
60
- C8 -
3M31
-
ERO1_YEAST
A:
[259-303]
-------------------------------------------------------------------------------------------------------------------------------
V
N
K
E
I
K
N
K
M
-------
D
N
V
I
S
Q
L
----
D
---
T
K
--
I
F
N
E
D
L
V
F
A
N
D
L
S
L
T
L
K
D
E
F
R
S
R
-------
F
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
64.11
15%
60
- C8 -
2K88
-
VATG_YEAST
A:
[1-60]
----------------------------------------------------------------------------------------------------------------
M
V
S
Q
K
--
N
-
G
I
A
T
L
L
Q
A
E
K
E
A
H
E
I
-------
V
S
K
A
R
K
Y
----
R
---
Q
D
--
K
L
K
Q
A
K
T
D
A
A
K
E
I
D
S
Y
K
I
Q
K
D
K
E
-------
L
K
E
F
-
E
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
63.30
33%
65
- C8 -
1RP4
-
ERO1_YEAST
A:
[260-304]
-------------------------------------------------------------------------------------------------------------------------------
V
N
K
E
I
K
N
K
M
-------
D
N
V
I
S
Q
L
----
D
---
T
K
--
I
F
N
E
D
L
V
F
A
N
D
L
S
L
T
L
K
D
E
F
R
S
R
-------
F
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
62.57
33%
61
- C8 -
3NVJ
-
ERO1_YEAST
A:
[260-304]
-------------------------------------------------------------------------------------------------------------------------------
V
N
K
E
I
K
N
K
M
-------
D
N
V
I
S
Q
L
----
D
---
T
K
--
I
F
N
E
D
L
V
F
A
N
D
L
S
L
T
L
K
D
E
F
R
S
R
-------
F
K
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
62.07
12%
17
- C6 -
4M6T
1
PAF1_HUMAN
A:
[1-183]
-------------------------------------------------------------------------------------------------KD
R
D
S
Q
I
T
A
I
E
K
T
F
E
D
A
Q
K
S
IS
Q
-
H
Y
S
K
P
R
V
T
P
V
E
V
M
P
V
-------
F
P
D
F
K
M
W
I
N
PC
A
---
Q
V
--
I
F
D
S
D
P
A
P
K
D
T
S
G
A
A
A
L
E
M
M
S
Q
A
-------
M
I
R
G
-
M
M
S
G
E
N
L
Y
F
Q
S
G
N
D
L
Y
F
V
K
L
P
N
F
L
-------
S
V
E
P
R
P
F
D
P
Q
YYEDEF
E
E
E
G
R
T
----
R
L
---------------
K
L
K
V
EN
T
I
R
W
R
I
R
R
D
EEG
N
E
I
K
E
---
S
N
---
A
---
R
I
------
V
K
W
SDG
S
M
-------
S
L
H
----
L
G
N
E
V
F
D
V
Y
K
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
60.47
18%
21
* C7 *
3MK7
8
CCON1_PSEST
A:
[5-470]
TSTAYSY
K
V
V
R
Q
F
A
I
M
T
V
V
W
G
I
V
G
M
G
L
G
V
F
I
A
A
Q
L
A
WPFLNFDLPWTS
F
G
R
L
R
P
L
H
T
N
A
V
I
F
A
F
G
G
C
A
L
F
A
T
S
Y
Y
S
V
Q
R
T
CQTTLFA
P
K
L
A
A
F
T
F
W
G
W
Q
L
V
I
L
L
A
A
I
S
L
P
L
-----------
G
F
T
---
S
S
K
E
Y
A
E
L
-------
E
W
P
I
D
I
L
----
I
---
T
I
--
V
W
V
A
Y
A
V
V
F
F
G
T
L
A
K
-
R
K
V
K
H
I
Y
-------
V
G
N
W
-
F
F
-
G
A
F
I
L
T
V
A
I
L
H
V
V
N
N
L
E
I
P
V
T
-------
A
M
K
S
Y
S
-----------
L
Y
A
G
A
----
T
D
---------------
A
M
V
Q
---
W
W
Y
G
H
N
A
-----
V
G
F
F
---
L
T
A
G
F
L
---
G
I
------
M
Y
-----
Y
-------
F
V
P
----
K
Q
A
E
R
P
V
Y
S
Y
R
L
S
I
V
H
F
W
A
L
I
T
V
Y
I
W
AGPHHLHYTALP
D
W
A
Q
S
L
G
M
V
M
S
L
I
L
L
A
P
S
W
G
G
M
I
N
G
M
M
T
L
SGA
W
H
K
L
R
S
D
P
I
L
R
F
L
V
V
S
L
A
F
Y
G
M
S
T
F
E
G
P
M
M
A
I
K
T
V
N
A
LSHYTD
W
T
I
G
H
V
H
A
G
A
LGW
V
A
M
V
S
I
G
A
L
Y
H
L
V
PKVFGREQMHS
I
G
L
I
N
T
H
F
W
L
A
T
I
G
T
V
L
Y
I
A
S
M
W
V
N
G
I
A
Q
G
L
M
W
R
AINDDGTLTYS
F
V
E
S
L
E
A
S
H
P
G
F
V
V
R
M
I
G
G
A
I
F
F
A
G
M
L
V
M
A
Y
N
T
W
R
T
V
Q
AAKPAEYDAA
42
Fugue
59.40
13%
18
- C3 -
4A0T
2
FIBER_BPT7
A:
[44-227]
------------------------------------------------------------------------------------------------------
M
G
H
V
L
Q
L
E
---
S
A
S
D
--
K
-
A
H
Y
I
L
S
K
D
G
N
R
N
N
W
Y
I
G
RGSDN
N
N
D
C
T
F
H
----
S
YVH
G
T
--
T
L
T
L
K
Q
D
Y
A
V
V
N
K
H
F
H
V
G
Q
A
V
V
A
-------
T
D
G
N
-
I
Q
-
G
T
K
W
G
G
K
W
L
D
A
Y
L
R
D
S
F
V
A
K
S
-------
K
A
W
T
Q
V
W
S
G
S
------
A
G
G
G
V
S
----
V
T
V
SQDLRF
R
N
I
W
I
K
C
A
N
N
S
W
---
N
F
F
R
T
G
P
-----
D
G
I
Y
---
F
I
---
A
SDG
G
W
------
L
R
-----
F
-------
Q
I
H
S---
N
G
L
G
F
K
N
I
A
D
S
R
S
V
P
N
A
I
M
V
E
N
E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
59.16
23%
76
* C9 *
2XYQ
1
A:
[96-151]
---------------------------------------------------------------------------------------------------------------------------------------
V
-------
D
S
D
L
N
D
F
----
V
---
S
-----
D
A
D
S
T
L
I
G
D
C
A
T
V
H
T
A
N
K
W
D
L
-------
I
I
S
D
-
M
Y
-
D
P
R
---
V
T
K
E
N
D
S
K
E
G
F
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
58.28
23%
76
- C9 -
2XYR
2
R1AB_CVHSA
A:
[96-151]
---------------------------------------------------------------------------------------------------------------------------------------
V
-------
D
S
D
L
N
D
F
----
V
---
S
-----
D
A
D
S
T
L
I
G
D
C
A
T
V
H
T
A
N
K
W
D
L
-------
I
I
S
D
-
M
Y
-
D
P
R
----
T
K
E
N
D
S
K
E
G
F
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
58.16
10%
-1
- C2 -
4BMD
2
A:
[11-198]
---------------------------------------------------------------------------------------------------K
L
F
K
N
L
T
F
Y
L
Y
----------------
E
F
P
N
T
K
V
S
R
L
-------
H
K
C
L
S
D
N
----
G
---
G
Q
--
I
S
E
F
L
S
S
T
I
D
F
V
V
I
P
H
Y
F
P
V
D
E
L
PIFS
F
P
T
V
N
E
W
-
W
I
-
E
R
C
L
Y
Y
K
K
I
F
G
I
D
E
H
A
L
A
K
P
F
-------
F
R
P
S
L
V
P
Y
F
N
------
G
L
S
I
H
L
T
GFK
G
E
---------------
E
L
S
H
---
L
K
K
A
L
T
I
-----
L
G
A
V
---
V
H
---
E
---
F
L
GVQRSI
L
L
-----
V
-------
N
T
N
EPFS
M
K
T
R
F
K
I
Q
H
A
T
E
W
N
V
R
V
V
G
V
A
W
L
W
N
I
I
Q
S
GKFIDQVSPWAID---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
55.78
23%
79
- C9 -
2XYV
1
A:
[96-151]
---------------------------------------------------------------------------------------------------------------------------------------
V
-------
D
S
D
L
N
D
F
----
V
---
S
-----
D
A
D
S
T
L
I
G
D
C
A
T
V
H
T
A
N
K
W
D
L
-------
I
I
S
D
-
M
Y
-
D
P
------
K
E
N
D
S
K
E
G
F
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.74
26%
73
- C8 -
4E0S
-
CO6_HUMAN
B:
[363-422]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
-------
L
K
N
S
G
L
T
-
E
E
E
A
K
H
C
V
R
I
E
T
K
K
R
V
L
F
A
K
K
TKVEHRC
T
T
N
K
L
S
E
K
H
E
------
G
S
F
I
Q
G
----
A
E
---------------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
54.68
26%
89
- C8 -
3T5O
1
CO6_HUMAN
A:
[363-443]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
-------
L
K
N
S
G
L
T
-
E
E
E
A
K
H
C
V
R
I
E
T
K
K
R
V
L
F
A
K
K
T
K
V
E
HRC
T
T
N
K
L
S
E
K
H
E
------
G
S
F
I
Q
G
----
A
E
---------------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
49.32
26%
89
- C4 -
4A5W
-
CO6_HUMAN
B:
[363-435]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
-------
L
K
N
S
G
L
T
-
E
E
E
A
K
H
C
V
R
I
E
T
---------HRC----
T
T
N
K
L
S
E
K
H
E
------
G
S
F
I
Q
G
----
A
E
---------------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
47.28
26%
-48
- C8 -
2JO1
-
PLM_HUMAN
A:
[20-46]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
V
I
-----
A
G
I
L
---
F
I
---
L
---
G
I
------
L
I
-----
V
-------
L
S
R
----
R
C
R
C
K
F
N
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------