@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0279: (2016-03-14 )
MMKDVKRIDYFSYEELTILGGSKLPLVNFELFDPSNFEEAKVALIEKELVTENDKLTDAGFKVATLVREYISAIVNIRINDMYFAPFSYEKDEYILLSRFKNNGFQIRIINKDIAWWSIVQSYPLLMRQEKSNDWDFKQIDDEILENLNNESIDTIGRVLEIEIYNHQGDPQQSLYNIYEQNDLLLIRYPLKDKVLNVHIGVINTFIRELFGFDTDENHINKAEE
Atome Classification :
(20 SA)
---------------------------------------.........10...---.----------....--20........30--------.......---..40......----..50..--.----------.-....60........70...-----.....------------80........90........100----------...-....110----.......--.120.......130...---------.....140......-.--150.....-.----..160------..---------------------.....------170....---...180.....------.----.-190-----------...---.---------.----.--.200......--------..210..------......220...--------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------MMKD
V
K
RIDYFSY
E
---
E
----------
L
T
I
L--GGSK
L
P
L
V
N
F
E
---------LFDPSN
F
---
E
E
A
K
V
A
L
I
E
K
----
E
LVTEN--D----------K-LTDA
G
F
K
V
A
T
L
V
R
E
Y
I
S
A
I
-----
V
N
I
R
I
------------N
D
M
Y
FAPFSYEKD
E
Y
I
L
L
S
RFKN----------N
G
F
-
Q
I
R
I
IN-----KD
I
A
W
W
S
--
I
V
Q
S
Y
P
L
L
M
RQE-KSND---------W
D
F
K
Q
I
D
D
E
I
L
E
NL-N--NE-
S
I
D
T
I-G----
R
V
L
E
I
------
E
I
---------------------YNHQG------
D
P
Q
Q
S
L
Y
---
N
I
YEQN
D
L
L
L
I
------R----Y-PLK-----------D
K
V
---
L
---------
N
----
V
--
H
I
-
G
V
I
N
T
F
I
--------
R
E
L
-FGF------DTDENHINKAEE--------------------------------
43
Fugue
85.24
19%
-8
- C6 -
4D0Y
7
?
A:
[1-184]
----------------------------------------
A
E
V
V
N
K
G
D
Y
Y
S
I
Q
G
KY
D
----------
E
I
I
V
--
A
N
K
H
Y
P
L
----------------
S
K
D
Y
---
N
P
G
E
N
P
T
A
K
A
----
E
L
V
K
L
I
--
K
----------
A
-
M
Q
E
A
G
F
P
---------------------
I
------------
S
D
H
Y
S
G
F
R
S
Y
E
T
Q
T
K
L
Y
Q
D
Y
V
N
Q
----------
D
G
K
-
E
A
A
D
R
Y
-----
S
A
R
P
G
Y
S
--
E
H
Q
T
G
L
A
F
D
V
I
G
-
T
D
G
D
------------
L
V
T
E
E
K
A
A
Q
W
L
-
L
--
D
H
-
A
A
D
Y
----------
G
F
------
V
V
---------------------
R
Y
L
K
G
------
K
E
K
E
T
G
Y
---
M
A
E
E
W
----
H
L
------
R
----
Y
-
V
G
K
-----------
E
---------------
A
----
K
--
E
I
-
A
E
S
G
L
S
L
--------
E
E
Y
-
Y
G
F
------
E
G
G
D
Y
V
D
-------------------------------------
36
Fugue
80.49
16%
-52
- C4 -
4XGC
-
A:
[38-388]
PCRE
R
E
F
E
N
I
Y
A
F
L
E
G
K
I
Q
D
QC
M
Y
V
S
G
V
PGTG
K
T
A
T
V
T
G
V
I
R
T
L
Q
E
Y
L
E
I
N
G
M
---
R
----------
L
T
E
P
--
R
Q
A
Y
V
Q
I
Y
K
Q
L
---------
T
G
K
T
V
S
W
---
E
Q
A
H
A
L
L
E
K
R
T
T
V
-
L
L
V
D
E
L
--
D
----------
I
-
L
C
N
R
R
Q
D
V
V
Y
N
L
L
D
W
P
T
K
L
-----
V
V
V
T
I
A
NTMDLPERLG
L
T
R
L
T
F
Q
P
Y
S
H
K
Q
L
Q
E
I
V
T
A
R
L
-
G
----------
K
G
E
-
A
V
Q
L
V
A
-----
R
K
V
A
A
V
S
GD
A
R
R
A
L
D
I
C
R
R
A
T
-
E
I
A
D
T
A
AVKCVT
M
L
H
V
Q
Q
A
L
A
E
M
I
A
S
A
-
K
--
V
Q
-
A
I
R
N
C
-
S
----
R
M
E
Q
I
F
L
Q
A
I
A
A
E
---------------------
V
T
R
T
G
------
V
E
E
T
T
F
M
---
G
V
Y
Q
Q
V
E
T
I
A
A
------
F
M
G
V
T
F
-
P
P
P
-----------
G
R
A
---
L
---------
R
----
L
C
S
K
L
-
G
A
E
R
L
I
I
S
E
HSRNDL
F
Q
K
-
I
L
L
------
N
V
S
A
D
D
I
H
Y
A
L
R
V-------------------------------
37
Fugue
75.47
18%
-49
- C4 -
4R6Y
2
PHNS_SALTY
A:
[1-317]
---------------SME
S
V
V
T
V
Y
S
I
D
GLHDGDNS
W
Y
Q
V
Q
F
D
A
F
T
K
A
T
G
I
T
V
R
---
Y
----------
V
E
G
G
--
G
G
V
V
V
E
R
L
A
K
E
RTNPQAD
V
L
V
T
A
P
P
F
I
---
Q
R
A
A
A
E
K
L
L
A
----
N
F
N
T
D
T
--
A
----------
S
A
I
P
D
A
N
N
L
Y
S
P
L
V
K
N
Y
L
S
F
I
-----
Y
N
S
K
L
--------------
L
K
T
A
P
A
S
W
---
Q
D
L
L
D
G
K
F
K
N
K
L
Q
Y
S
T
PGQA
A
D
G
-
T
A
V
M
L
Q
-----
A
F
H
S
F
G
S
--
K
D
A
G
F
A
Y
L
G
K
L
Q
-
A
N
N
V
---------
G
P
S
A
S
T
G
-
K
L
T
A
L
V
-
N
--
K
G
-
E
I
Y
V
A
-
N
----
G
D
L
Q
M
------
N
L
---------------------
A
Q
M
E
R
------
N
P
N
V
K
I
F
W
P
A
N
D
K
G
E
R
S
A
L
A
I
------
P
----
Y
-
V
I
G
L
V
Q
GAPQ
S
E
N
G
K
K
L
---
I
---------
N
----
F
--
L
L
S
K
E
A
Q
T
R
V
--------
S
E
L
S
W
G
M
PVRSDV
T
P
S
D
E
H
Y
K
A
A
T
A
A
L
EG
V
Q
S
W
Q
P
N
W
D
D
V
A
V
S
L
S
A
D
I
S
R
W
H
K
V
T
E
S
45
Fugue
71.99
16%
-52
- C1 -
3N7X
3
?
A:
[31-329]
------------------------GPDPHR
C
L
Q
F
N
T
G
D
S
I
H
I
T
F
Q
T
R
R
Y
F
E
F
D
---
A
ANDGNFDGK
N
L
Y
C
L
PL
H
W
M
N
L
Y
L
Y
G
L
K
---------
S
S
D
S
S
A
T
---
E
T
Q
R
Y
K
M
V
K
S
----
M
M
K
T
Y
G
--
W
----------
K
-
V
H
K
A
G
V
V
M
H
S
M
V
P
L
M
K
D
L
K
-----
V
S
---------------
G
G
T
S
F
E
T
L
T
F
T
D
T
P
Y
L
E
I
F
K
D
T
T
----------
G
L
H
N
Q
L
S
T
K
E
-----
T
D
V
T
L
A
K
--
W
I
Q
N
P
Q
L
V
T
V
Q
S
-
T
A
A
N
---------
Y
E
D
P
I
Q
Q
F
G
F
M
E
Q
M
-
R
TG
D
R
-
K
A
Y
T
I
-
H
G
DTR
N
W
Y
G
G
------
E
I
PTT
G
P
T
F
I
P
K
W
G
GQ
I
K
W
D
K
P
S
L
G
N
L
V
------
Y
P
A
D
H
H
T
---
N
D
W
Q
Q
---
I
F
M
------
R
----
M
S
P
I
K
-----------
G
P
N
GDE
L
---------
K
----
L
--
G
C
-
R
V
Q
A
D
F
F
--------
L
H
L
-
E
V
R
------
L
P
P
Q
G
C
V
A
S
L
G
M
LQY
L
H
A
P
C
T
G
Q
LN
K
C
Y
I
M
H
TN-----------
39
Fugue
66.13
15%
-40
- C2 -
3B21
-
?
A:
[21-212]
---------------------------------------
N
V
N
V
K
K
L
L
E
S
L
N
S
K
---
S
----------
L
----------------------------
G
D
M
D
---
K
D
S
E
L
A
A
T
L
Q
----
K
M
I
N
P
-----------------
S
G
G
D
G
N
C
S
G
C
A
L
H
A
C
M
A
M
-----
L
G
Y
G
V
------------
R
E
---
A
P
V
P
N
E
I
S
E
Y
--
M
T
G
F
F
H
----------
R
H
L
-
E
Q
I
D
S
E
-----
G
---------
I
V
S
H
P
----------
N
---------
E
T
Y
S
K
F
R
E
R
I
A
E
N
I
-
L
--
Q
N
-
T
--
S
K
-
G
----
S
V
V
M
I
------
S
I
-------------------------
E
------
Q
A
T
H
W
I
A
---
G
F
N
D
G
E
K
I
M
F
L
DVQTGK
G
----
F
-
N
L
Y
-----------
D
P
V
---
E
K
S
PDAFVDE
N
----
S
--
S
V
-
Q
V
I
H
V
S
D
--------
Q
E
F
-
D
H
Y
------
A
N
S
S
S
W
K
S
K
R
L
C
--------------------------------
40
Fugue
63.36
12%
-31
- C6 -
1G61
-
IF6_METJA
A:
[2003-2227]
------------------------------------------
M
I
I
R
K
Y
F
S
G
I
P
---
T
----------
I
G
V
L
--
A
L
T
T
E
E
I
T
L
L
-------------
P
I
F
L
---
D
K
D
D
V
N
E
V
S
E
----
V
L
E
T
K
C
--
L
----------
Q
-
T
N
I
G
G
S
S
L
-------
V
G
S
L
-----
S
V
A
N
K
------------
Y
G
L
L
L
P
K
I
V
E
D
E
E
L
D
R
I
K
N
F
L
K
E
----------
N
N
L
-
D
L
N
V
E
I
IKSKN
T
A
L
G
N
L
I
--
L
T
N
D
K
G
A
L
I
S
P
E
L
K
D
F
K
---------
K
D
I
E
D
S
L
N
V
E
V
E
I
G
-
T
--
I
A
-
E
L
P
T
V
-
G
----
S
N
A
V
V
------
T
N
---------------------
K
G
C
L
T
------
H
P
L
V
E
D
D
---
E
L
E
F
L
K
S
L
F
K
V
------
E
----
Y
-
I
G
K
-----------
G
T
A
---
N
---------
K
GTTS
V
--
G
A
-
C
I
I
A
N
S
K
--------
G
A
V
-
V
G
G
------
D
T
T
G
P
E
L
L
I
I
E
D
A
L
GL----------------------------
30
HHSearch
51.59
31%
5
- C5 -
2PG4
2
?
A:
[49-91]
-------------------------------------------------------------------------------------------------------
M
G
L
K
D
R
L
I
R
A
----
G
L
V
K
E
E
T
L
S
YR
V
K
T
L
----
K
-
L
T
E
K
G
R
R
L
A
E
C
L
E
K
C
R
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
47.95
24%
21
- C5 -
2QVO
-
Y1382_ARCFU
A:
[44-87]
------------------------------------------------------------------------------------------------
H
S
Y
V
---
W
L
I
I
K
K
F
E
E
A
----
K
M
V
E
C
E
--
L
EGR
T
K
I
I
---
R
-
L
T
D
K
G
Q
K
I
A
Q
Q
I
K
S
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
47.35
38%
-8
- C5 -
2BJG
-
CBH_CLOPE
A:
[86-129]
------------------------------------------------
Y
V
S
Y
S
---
K
----------
E
D
I
E
--
G
K
T
N
I
P
V
Y
N
F
L
---------
L
W
V
L
A
N
F
SS
V
E
E
V
K
E
A
L
K
N
A
----
N
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.94
30%
39
- C5 -
2P67
2
ARGK_ECOLI
A:
[271-325]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
Q
Q
-
Q
S
V
E
---------
W
L
R
K
Q
T
E
E
E
V
L
N
H
L
F
A
--
N
E
-
D
F
D
R
Y
-
Y
----
R
Q
T
L
L
------
A
V
---------------------
K
N
N
T
L
------
S
P
R
T
G
L
R
---
Q
L
S
E
-------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
46.72
14%
20
- C5 -
1BJA
1
MOTA_BPT4
A:
[43-87]
----------------------------------------------------------------------------------------------
L
G
N
A
V
V
---
N
S
N
I
G
V
L
I
K
K
----
G
L
V
E
K
S
--
G
D
G
L
-------
I
-
I
T
G
E
A
Q
D
I
I
S
N
A
A
T
L
Y
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
46.01
33%
49
- C5 -
2PUS
-
RDRP_IBDV
A:
[506-566]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
R
Q
P
-
R
P
D
S
---------
E
E
F
K
S
I
E
D
K
L
G
I
N
F
-
K
--
I
E
R
S
I
D
D
I
R
G
----
K
L
R
Q
L
------
V
L
---------------------
L
A
Q
P
G
YLSGGV
E
P
E
Q
S
----------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
45.59
21%
41
- C5 -
2PEX
1
?
A:
[74-121]
-----------------------------------------------------------------------------------------------
D
S
A
T
L
---
T
P
L
L
K
R
L
Q
A
A
----
G
L
V
T
R
T
--
R
V
I
I
-------
A
-
L
T
E
T
G
R
A
L
R
S
K
A
G
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
44.97
38%
18
- C5 -
2BJF
1
CBH_CLOPE
A:
[86-129]
------------------------------------------------
Y
V
S
Y
S
---
K
----------
E
D
I
E
--
G
K
T
N
I
P
V
Y
N
F
L
---------
L
W
V
L
A
N
F
SS
V
E
E
V
K
E
A
L
K
N
A
----
N
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
44.70
38%
3
- C5 -
2RF8
-
CBH_CLOPE
A:
[86-129]
------------------------------------------------
Y
V
S
Y
S
---
K
----------
E
D
I
E
--
G
K
T
N
I
P
V
Y
N
F
L
---------
L
W
V
L
A
N
F
SS
V
E
E
V
K
E
A
L
K
N
A
----
N
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
44.36
22%
52
- C5 -
3BRO
1
?
A:
[63-109]
-----------------------------------------------------------------------------------------------
K
S
S
T
A
---
T
V
L
L
Q
R
M
E
I
K
----
K
L
L
Y
R
K
--
V
SGKDSR
Q
K
C
L
K
-
L
T
K
K
A
N
K
L
E
T
I
I
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
43.61
23%
13
* C4 *
2KSL
-
TXI1_ERAAG
A:
[1-51]
------------------------------------------------------------------------------------------------
S
E
P
D
---
E
I
C
R
A
R
M
T
H
K
----
E
F
N
Y
K
S
--
N
----------
V
-
C
N
G
C
G
D
Q
V
A
A
C
E
A
E
C
F
R
------------------------
N
D
V
Y
T
A
C
H
E
A
Q
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
42.83
38%
15
- C5 -
2RG2
-
CBH_CLOPE
A:
[85-128]
------------------------------------------------
Y
V
S
Y
S
---
K
----------
E
D
I
E
--
G
K
T
N
I
P
V
Y
N
F
L
---------
L
W
V
L
A
N
F
SS
V
E
E
V
K
E
A
L
K
N
A
----
N
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
42.29
33%
49
- C5 -
2PGG
-
RDRP_IBDV
A:
[506-571]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
R
Q
P
-
R
P
D
S
---------
E
E
F
K
S
I
E
D
K
L
G
I
N
F
-
K
--
I
E
R
S
I
D
D
I
R
G
----
K
L
R
Q
L
------
V
L
---------------------
L
A
Q
P
G
YLSGGV
E
P
E
Q
S
----------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.26
23%
7
- C5 -
1H54
-
?
A:
[612-701]
--------------------------------------------
K
K
A
N
F
D
F
Y
E
---
P
----------
L
T
V
H
--
E
S
S
L
S
P
A
I
H
S
V
---------
L
A
A
D
L
H
Y
---
E
D
K
A
V
E
L
Y
S
R
TARL
D
L
D
N
Y
N
--
N
----------
D
-
T
T
D
-
G
L
H
I
T
S
M
T
G
A
W
I
A
V
V
QGFAG
M
R
V
R
D
------------
G
Q
L
H
Y
A
P
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------