@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0668: (2016-03-17 )
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPKAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIRFPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI
Atome Classification :
(20 SA)
--.........10--..---.......20---........30-....---------------.....40..-..----....50.....--.---.---.---------60-----........-.--70.--------.-......80........90.......-.100.......---110---------------------------.---...---.....-----120-------.---.......130......-.--140-.....-.-.150-----.......160..-.....170.......180.......190.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--
M
I
L
V
I
DNND
S
---
F
T
---
Y
N
L
I
D
Y
IKT---Q
T
K
L
T
V
Q
V
V--GI
D
N
---------------
L
L
I
E
D
V
INM-KP----
K
A
I
V
I
SPGPGN--P---D---D---------
Y
------
P
I
L
N
E
V
L
E
-
Q
--
F
Y
Q
--------R-V
P
I
L
G
V
C
L
G
F
Q
C
I
V
S
YFGGN
I
I
H
GY-HPVHG
H
T
T
Q
L
R---H-----------------------------T---N
E
G
---
I
F
QGL-----PQ--------N---F
N
V
M
R
Y
H
S
L
IADGATF-P--
N
C
L
-
K
I
TAK-N-D
E
A
I
-----
I
M
A
F
E
HIRF
P
V
F
-
G
V
Q
YH
P
E
S
I
L
S
EYG
Y
R
Q
V
E
L
F
L
S
K
V
G
D
Y
C
ENRI
2
PsiBlast_PDB
91.59
37%
-138
- C2 -
1I7S
-
TRPG_SERMA
B:
[4-188]
---
I
L
L
L
D
N
V
D
S
---
F
T
---
Y
N
L
V
D
Q
L
R
A
S
G
H
Q
V
V
I
Y
R
N
Q
I
--
G
A
E
----------------
V
I
I
E
R
L
Q
H
M
-
E
Q
----
P
V
L
M
L
S
P
G
P
G
T
--
P
---
S
---
E
---------
A
------
G
C
M
P
E
L
L
Q
-
R
--
L
R
G
--------
Q
-
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
-
E
I
L
H
G
K
A
S
A
I
A
---
H
-----------------------------
D
---
G
E
G
---
M
F
A
G
M
-----
A
N
--------
P
---
L
P
V
A
R
Y
H
S
L
V
--
G
S
N
I
-
P
--
A
D
L
-
T
V
N
A
R
-
F
-
G
E
-
M
-----
V
M
A
V
R
D
D
R
R
R
V
C
-
G
F
Q
F
H
P
E
S
I
L
T
T
H
G
A
R
L
L
E
Q
T
L
A
----------
1
PsiBlast_PDB
91.14
37%
-137
- C2 -
1I7Q
1
TRPG_SERMA
B:
[4-188]
---
I
L
L
L
D
N
V
D
S
---
F
T
---
Y
N
L
V
D
Q
L
R
A
S
G
H
Q
V
V
I
Y
R
N
Q
I
--
G
A
E
----------------
V
I
I
E
R
L
Q
H
M
-
E
Q
----
P
V
L
M
L
S
P
G
P
G
T
--
P
---
S
---
E
---------
A
------
G
C
M
P
E
L
L
Q
-
R
--
L
R
G
--------
Q
-
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
-
E
I
L
H
G
K
A
S
A
I
A
---
H
-----------------------------
D
---
G
E
G
---
M
F
A
G
M
-----
A
N
--------
P
---
L
P
V
A
R
Y
H
S
L
V
--
G
S
N
I
-
P
--
A
D
L
-
T
V
N
A
R
-
F
-
G
E
-
M
-----
V
M
A
V
R
D
D
R
R
R
V
C
-
G
F
Q
F
H
P
E
S
I
L
T
T
H
G
A
R
L
L
E
Q
T
L
A
----------
21
PsiBlast_CBE
90.96
37%
-140
- C2 -
1I7Q
1
TRPG_SERMA
D:
[4-188]
---
I
L
L
L
D
N
V
D
S
---
F
T
---
Y
N
L
V
D
Q
L
R
A
SGH
Q
V
V
I
Y
R
N
Q
I
--
G
A
E
----------------
V
I
I
E
R
L
Q
H
M
-
E
Q
----
P
V
L
M
L
S
P
G
P
G
T
--
P
---
S
---
E
---------
A
------
G
C
M
P
E
L
L
Q
-
R
--
L
R
G
--------
Q
-
L
P
I
I
G
I
C
L
G
H
Q
A
I
V
E
A
Y
G
G
Q
V
G
Q
A
G
-
E
I
L
H
G
K
A
S
A
I
A
---
H
-----------------------------
D
---
G
E
G
---
M
F
A
G
M
-----
A
N
--------
P
---
L
P
V
A
R
Y
H
S
L
V
--
G
S
N
I
-
P
--
A
D
L
-
T
V
N
A
R
-
F
-
G
E
-
M
-----
V
M
A
V
R
D
D
R
R
R
V
C
-
G
F
Q
F
H
P
E
S
I
L
T
T
H
G
A
R
L
L
E
Q
T
L
A
----------
54
Fugue
87.11
34%
-147
* C2 *
1QDL
-
TRPG_SULSO
B:
[1-195]
M
D
L
T
L
I
I
D
N
Y
D
S
---
F
V
---
Y
N
I
A
Q
I
V
G
E
----
L
G
S
Y
P
I
V
I
--
R
N
D
E
---------------
I
S
I
K
G
I
E
R
I
-
D
P
----
D
R
L
I
I
S
P
G
P
G
T
--
P
EKR
E
---
D
---------
I
------
G
V
S
L
D
V
I
K
-
Y
--
L
G
K
---------R
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
-
K
V
F
H
G
K
I
S
N
I
I
L
VN
N
-----------------------------
S
---
P
L
S
---
L
Y
Y
G
I
-----
A
----------K
E
-
F
K
A
T
R
Y
H
S
L
V
V
D
--
E
V
-
H
--
R
P
L
-
I
V
D
A
I
S
A
-
E
D
N
E
-----
I
M
A
I
H
H
E
E
Y
P
I
Y
-
G
V
Q
F
H
P
E
S
V
G
T
S
L
G
Y
K
I
L
Y
N
F
L
N
R
V
--------
31
HHSearch
86.86
34%
-142
- C2 -
1QDL
-
TRPG_SULSO
B:
[3-195]
--
L
T
L
I
I
D
N
Y
D
S
---
F
V
---
Y
N
I
A
Q
I
V
G
E
----
L
G
S
Y
P
I
V
I
--
R
N
D
E
---------------
I
S
I
K
G
I
E
R
I
-
D
P
----
D
R
L
I
I
S
P
G
P
G
T
--
P
---
E
---
K
---------
R
EDI---
G
V
S
L
D
V
I
K
-
Y
--
L
G
K
--------
R
-
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
-
K
V
F
H
G
K
I
S
N
I
I
---
L
-----------------------------
V
NNS
P
L
S
---
L
Y
Y
G
I
-----
A
K
--------
E
---
F
K
A
T
R
Y
H
S
L
V
V
D
--
E
V
-
H
--
R
P
L
-
I
V
D
A
I
-
S
A
E
D
N
E
-----
I
M
A
I
H
H
E
E
Y
P
I
Y
-
G
V
Q
F
H
P
E
S
V
G
T
S
L
G
Y
K
I
L
Y
N
F
L
N
R
V
--------
3
PsiBlast_PDB
85.40
34%
-131
- C2 -
1QDL
-
TRPG_SULSO
B:
[3-195]
--
L
T
L
I
I
D
N
Y
D
S
---
F
V
---
Y
N
I
A
Q
I
V
G
E
---
L
G
S
Y
P
I
-
V
I
--
R
N
D
E
---------------
I
S
I
K
G
I
E
R
I
-
D
P
----
D
R
L
I
I
S
P
G
P
G
T
--
P
---
E
KRE
D
---------
I
------
G
V
S
L
D
V
I
K
-
Y
--
L
G
K
--------
R
-
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
Y
A
F
G
A
K
I
R
R
A
R
-
K
V
F
H
G
K
I
S
N
I
I
---
L
-----------------------------
V
---
N
N
S
PLS
L
Y
Y
G
I
-----
A
K
--------
E
---
F
K
A
T
R
Y
H
S
L
V
V
D
E
V
H
R
-
P
--
L
I
V
D
A
I
S
A
E
-
D
-
N
E
-------
I
M
A
I
H
H
E
E
Y
P
I
Y
-
G
V
Q
F
H
P
E
S
V
G
T
S
L
G
Y
K
I
L
Y
N
F
L
N
R
V
--------
26
HHSearch
76.14
26%
-118
- C2 -
2A9V
3
GUAAA_THEAC
A:
[15-206]
--
K
I
Y
V
V
D
N
G
G
Q
---
W
T
---
H
R
E
W
R
V
L
R
E
----
L
G
V
D
T
K
I
V
--
P
N
D
I
----------------
D
S
S
E
L
--
D
-
G
L
----
D
G
L
V
L
S
G
G
A
P
N
--
I
---
D
---
E
---------
E
L-----
D
K
L
G
S
V
G
K
-
Y
I
-
D
D
H
--------
N
-
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
L
H
F
G
A
S
V
V
K
A
K
-
H
P
E
F
G
-
K
T
K
V
S
---
V
M----------------------------
H
---
S
E
N
---
I
F
G
G
L
-----
P
S
--------
E
---
I
T
V
W
E
N
H
N
D
E
I
I
--
N
L
-
P
--
D
D
F
-
T
L
A
A
S
-
S
-
A
T
C
Q
-----
V
Q
G
F
Y
H
K
T
R
P
I
Y
-
A
T
Q
F
H
P
E
V
E
H
T
Q
Y
G
R
D
I
F
R
N
F
I
G
I
C
A
S
Y
R
E
I
Q
-
4
PsiBlast_PDB
75.81
29%
-109
- C2 -
2D7J
-
GUAAA_PYRHO
A:
[2-188]
--
M
I
V
I
M
D
N
G
G
Q
---
Y
V
H
R
I
W
R
T
L
R
Y
L
G
V
---
E
T
K
I
I
P
-------
N
T
---------------
T
P
L
E
E
I
K
A
M
-
N
P
----
K
G
I
I
F
S
G
G
P
-
S
--
L
---
E
---
N
---------
T
------
G
N
C
E
K
V
L
E
-
H
--
Y
D
E
F-------
N
-
V
P
I
L
G
I
C
L
G
H
Q
L
I
A
K
F
F
G
G
K
V
G
R
G
E
-
K
A
E
Y
S
L
V
E
I
E
I
---
I
-----------------------------
D
---
E
D
E
---
I
F
K
G
L
-----
P
K
--------
R
---
L
K
V
W
E
S
H
--
M
D
E
V
K
E
L
-
P
--
P
K
F
-
K
I
L
A
R
-
S
-
E
T
C
P
-----
I
E
A
M
K
H
E
E
L
P
I
Y
-
G
V
Q
F
H
P
E
V
A
H
T
E
K
G
E
E
I
L
R
N
F
A
K
L
C
G
E
------
5
PsiBlast_PDB
73.09
25%
-117
- C2 -
2YWB
-
GUAA_THET8
A:
[1-214]
--
M
V
L
V
L
D
F
G
S
Q
---
Y
T
---
R
L
I
A
R
R
L
R
E
---
L
R
A
F
S
L
I
L
P
--
G
--
D
---------------
A
P
L
E
E
V
L
K
H
-
R
P
----
Q
A
L
I
L
S
G
G
P
R
S
VF
D
---
P
---
D
---------
A
------
P
R
P
D
P
R
L
-----
F
S
S
--------
G
-
L
P
L
L
G
I
C
Y
G
M
Q
L
L
A
Q
E
L
G
G
R
V
E
R
A
----
E
Y
G
K
A
L
L
T
R
---
H
-----------------------------
E
---
G
P
----
L
F
R
G
L
-----
E
G
--------
E
---
V
Q
V
W
M
S
H
Q
---
D
A
V
T
A
P
P
--
P
G
W
-
R
V
V
A
E
-
T
-
E
E
N
P
-----
V
A
A
I
A
S
P
D
G
R
A
Y
-
G
V
Q
F
H
P
E
V
A
H
T
P
K
G
M
Q
I
L
E
N
F
L
E
L
A
G
-------
6
PsiBlast_PDB
72.14
25%
-111
- C2 -
2YWC
-
GUAA_THET8
A:
[2-213]
---
V
L
V
L
D
F
G
S
Q
---
Y
T
---
R
L
I
A
R
R
L
R
E
---
L
R
A
F
S
L
I
L
P
--
G
--
D
---------------
A
P
L
E
E
V
L
K
H
-
R
P
----
Q
A
L
I
L
S
G
G
P
R
S
VF
D
---
P
---
D
---------
A
------
P
R
P
D
P
R
L
-----
F
S
S
--------
G
-
L
P
L
L
G
I
C
Y
G
M
Q
L
L
A
Q
E
L
G
G
R
V
E
R
A
G
-
R
A
E
Y
G
K
A
L
L
T
R
---
H
-----------------------------
E
---
G
P
----
L
F
R
G
L
-----
E
G
--------
E
---
V
Q
V
W
M
S
H
Q
---
D
A
V
T
A
P
P
--
P
G
W
-
R
V
V
A
E
-
T
-
E
E
N
P
-----
V
A
A
I
A
S
P
D
G
R
A
Y
-
G
V
Q
F
H
P
E
V
A
H
T
P
K
G
M
Q
I
L
E
N
F
L
E
L
A
G
-------
36
HHSearch
71.13
24%
-137
- C2 -
3TQI
-
GUAA_COXBU
A:
[9-241]
--
R
I
L
I
L
D
F
G
S
Q
---
Y
A
---
Q
L
I
A
R
R
V
R
E
----
I
G
V
Y
C
E
L
M
--
P
C
D
I
----------------
D
E
E
T
I
R
D
F
-
N
P
----
H
G
I
I
L
S
G
G
P
E
---------------------------------
A
P
A
-
F
I-
F
E
I
--------
G
-
C
P
V
L
G
I
C
Y
G
M
Q
T
M
A
Y
Q
L
G
G
K
V
N
------
E
F
G
H
-
A
Q
L
R
---
V
L
----------------------------
N
---
P
A
F
---
L
F
D
G
I
-----
E
D
QVSPQG
E
P
L
---
L
D
V
W
M
S
H
G
D
I
V
S
--
E
L
-
P
--
P
G
F
-
E
A
T
A
C
-
T
-
D
N
S
P
-----
L
A
A
M
A
D
F
K
R
R
F
F
-
G
L
Q
F
H
P
E
V
T
H
T
P
Q
G
H
R
I
L
A
H
F
V
I
H
---------
30
HHSearch
71.11
24%
-121
- C2 -
2YWB
-
GUAA_THET8
A:
[1-216]
--
M
V
L
V
L
D
F
G
S
Q
---
Y
T
---
R
L
I
A
R
R
L
R
E
----
L
R
A
F
S
L
I
L
--
P
G
D
A
----------------
P
L
E
E
V
L
K
H
-
R
P
----
Q
A
L
I
L
S
G
G
P
R
S
--
V
---
F
---
D
---------
P
------
D
A
-
P
R
P
D
P
-
R
L-
F
S
S
--------
G
-
L
P
L
L
G
I
C
Y
G
M
Q
L
L
A
Q
E
L
G
G
R
V
E
R
A
----
E
Y
G
K
-
A
L
L
T
---
R
-----------------------------
H
---
E
G
P
---
L
F
R
G
L
-----
E
G
--------
E
---
V
Q
V
W
M
S
H
Q
D
A
V
T
--
A
P
-
P
--
P
G
W
-
R
V
V
A
E
-
T
-
E
E
N
P
-----
V
A
A
I
A
S
P
D
G
R
A
Y
-
G
V
Q
F
H
P
E
V
A
H
T
P
K
G
M
Q
I
L
E
N
F
L
E
L
A
G
V
K
-----
7
PsiBlast_PDB
70.73
24%
-90
- C2 -
2A9V
3
GUAAA_THEAC
A:
[16-204]
---
I
Y
V
V
D
N
G
G
Q
---
W
T
---
H
-----------
R
E
W
R
V
L
R
E
L
--
G
V
D
T
---------------
K
I
V
P
N
D
I
D
S
-
S
E
LDGL
D
G
L
V
L
S
G
G
A
-----------------------------
P
N
I
D
E
E
L
D
-
K
--
L
G
S
V
G
K
Y
I
D
D
H
N
-
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
L
H
F
G
A
S
V
V
K
A
K
-
H
P
E
F
G
K
T
K
V
S
V
---
M
-----------------------------
H
---
S
E
N
---
I
F
G
G
L
-----
P
S
--------
E
---
I
T
V
W
E
N
H
N
--
D
E
I
I
N
L
-
P
--
D
D
F
-
T
L
A
A
S
-
S
-
A
T
C
Q
-----
V
Q
G
F
Y
H
K
T
R
P
I
Y
-
A
T
Q
F
H
P
E
V
E
H
T
Q
Y
G
R
D
I
F
R
N
F
I
G
I
C
A
S
Y
R
E
---
35
HHSearch
69.97
21%
-130
- C2 -
3UOW
-
?
A:
[9-256]
--
K
I
L
V
L
N
F
G
S
Q
---
Y
F
---
H
L
I
V
K
R
L
N
N
----
I
K
I
F
S
E
T
K
--
D
Y
G
V
----------------
E
L
K
D
I
K
D
M
-
N
I
----
K
G
V
I
L
S
G
G
P
Y
S
--
V
---
T
---
E
---------
A
GSP---
H
L
K
K
E
V
F
E
-
Y
F
-
L
E
K
--------
K
-
I
P
I
F
G
I
C
Y
G
M
Q
E
I
A
V
Q
M
N
G
E
V
K
K
S
K
-
T
S
E
Y
G
C
T
D
-
V
N
---
I
L
R
NDNINNITYCRNFSS
A
M
D
L
Y
S
N
Y
K
L
M
N-----
C
C
---
L
F
E
N
I
-----
K
S
D-------
I
---
T
T
V
W
M
N
H
N
D
E
V
T
--
K
I
-
P
--
E
N
F
-
Y
L
V
S
S
-
S
-
E
N
C
L
-----
I
C
S
I
Y
N
K
E
Y
N
I
Y
-
G
V
Q
Y
H
P
E
V
Y
E
S
L
D
G
E
L
M
F
Y
N
F
A
Y
N
---------
33
HHSearch
67.90
20%
-120
- C2 -
1GPM
1
GUAA_ECOLI
A:
[9-223]
--
R
I
L
I
L
D
F
G
S
Q
---
Y
T
---
Q
L
V
A
R
R
V
R
E
----
L
G
V
Y
C
E
L
W
--
A
W
D
V
----------------
T
E
A
Q
I
R
D
F
-
N
P
----
S
G
I
I
L
S
G
G
P
E
S
--
T
---
T
---
E
---------
E
------
N
-
S
P
R
A
P
Q
-
Y
V-
F
E
A
--------
G
-
V
P
V
F
G
V
C
Y
G
M
Q
T
M
A
M
Q
L
G
G
H
V
E
A
S
N
-
E
R
E
F
G
Y
-
A
Q
V
E
---
V
-----------------------------
V
N--
D
S
A
---
L
V
R
G
I
-----
E
D
ALTADG
K
P
L
---
L
D
V
W
M
S
H
G
D
K
V
T
--
A
I
-
P
--
S
D
F
-
I
T
V
A
S
-
T
-
E
S
C
P
-----
F
A
I
M
A
N
E
E
K
R
F
Y
-
G
V
Q
F
H
P
E
V
T
H
T
R
Q
G
M
R
M
L
E
R
F
V
R
D
I
--------
34
HHSearch
64.99
20%
-135
- C2 -
2VPI
-
GUAA_HUMAN
A:
[27-214]
--
A
V
V
I
L
D
A
G
A
Q
---
Y
G
---
K
V
I
D
R
R
V
R
E
----
L
F
V
Q
S
E
I
F
--
P
L
E
T
----------------
P
A
F
A
I
K
E
Q
-
G
F
----
R
A
I
I
I
S
G
----------------------------------
A
P
W
F
D
-
P
AI
F
T
I
--------
G
-
K
P
V
L
G
I
C
Y
G
M
Q
M
M
N
K
V
F
G
G
T
V
H
K
K
S
-
V
R
E
D
G
-
V
F
N
I
S
---
V
D----------------------------
N
---
T
C
S
---
L
F
R
G
L
-----
Q
K
--------
E
---
E
V
V
L
L
T
H
G
D
S
V
D
--
K
V
-
A
--
D
G
F
-
K
V
V
A
R
-
S
-
G
-
N
I
-----
V
A
G
I
A
N
E
S
K
K
L
Y
-
G
A
Q
F
H
P
E
V
G
L
T
E
N
G
K
V
I
L
K
N
F
L
Y
D
I
A
G
C
S
----
37
HHSearch
63.21
21%
-138
- C2 -
2VXO
-
GUAA_HUMAN
A:
[31-222]
--
A
V
V
I
L
D
A
G
-----
Y
G
---
K
V
I
D
R
R
V
R
E
----
L
F
V
Q
S
E
I
F
--
P
L
E
T
----------------
P
A
F
A
I
K
E
Q
-
G
F
----
R
A
I
I
I
S
G
G
P
--------------------------------
A
P
W
F
D
P
A
I-
F
T
I
--------
G
-
K
P
V
L
G
I
C
Y
G
M
Q
M
M
N
K
V
F
G
G
T
V
H
K
---------
V
F
N
I
S
---
V
D----------------------------
N
---
T
C
S
---
L
F
R
G
L
-----
Q
K
--------
E
---
E
V
V
L
L
T
H
G
D
S
V
D
--
K
V
-
A
--
D
G
F
-
K
V
V
A
R
-
S
-
G
N
-
I
-----
V
A
G
I
A
N
E
S
K
K
L
Y
-
G
A
Q
F
H
P
E
V
G
L
T
E
N
G
K
V
I
L
K
N
F
L
Y
----------
42
HHSearch
61.01
20%
-129
- C2 -
2H2W
-
META_THEMA
A:
[37-240]
--
E
I
L
I
L
N
L
M
P
D
K
I
K
T
E
---
I
Q
L
L
R
L
L
G
N
----
T
P
L
Q
V
N
V
T
L
L
Y
T
E
T
HKPKHTP
I
E
H
I
L
K
FY
T
T
F
S
A
V
K
D
R
-
K
F
----
D
G
F
I
I
T
G
A
P
V
E
--
L
---
L
---
P
---------
F
EEVDY
W
E
E
L
T
E
I
M
E
-
W
S
-
R
H
N
--------
V
-
Y
S
T
M
F
I
C
W
A
A
Q
A
G
L
Y
Y
F
Y
G
I
P
K
Y
E
L
P
Q
K
L
S
G
-
V
Y
K
H
R
---
V
A----------------------------
K
---
D
S
V
---
L
F
R
G
H
-----
D
D
--------
F
---
F
W
A
P
H
S
R
Y
T
E
V
K
K
E
D
I
-
D
K
V
P
E
L
-
E
I
L
A
E
-
S
-
D
E
A
G
-----
V
Y
V
V
A
N
K
S
E
R
Q
I
-
F
V
T
G
H
P
E
Y
D
R
Y
----------------------
20
PsiBlast_PDB
60.79
23%
-113
- C2 -
3R74
-
?
A:
[448-622]
----
L
I
V
D
A
E
D
H
---
F
T
----
A
M
I
A
Q
Q
L
S
---
S
L
G
L
A
T
E
V
C
--
G
V
--------------------
H
D
A
V
D
L
A
R
Y
----
D
V
V
V
M
G
P
G
P
G
D
--
P
---
S
---
D
AGD
P
R
I
A
R
L
Y
------
A
W
L
R
H
L
I
D
------
E
--------
G
-
K
P
F
M
A
V
C
L
S
H
Q
I
L
N
A
I
L
G
I
P
L
V
R
R
E
-
V
P
N
Q
G
I
Q
V
E
I
----------------------------------------
D
---
L
F
G
--------
Q
--------
R
---
E
R
V
G
F
Y
N
T
Y
V
A
Q
--
T
V
-
R
--
D
E
M
-
D
V
D
G
V
-
G
-
T
V
A
I
S
R
DPR
T
G
E
V
H
A
L
R
G
P
T
F
S
S
M
Q
F
H
A
E
S
V
L
T
V
D
G
P
R
-----------------
16
PsiBlast_PDB
59.58
27%
-141
- C2 -
3TQI
-
GUAA_COXBU
A:
[44-239]
-----------------------------------------------------------------
E
T
I
R
D
F
-
N
P
----
H
G
I
I
L
S
G
G
P
E
--------------------------------
A
P
A
F
-
I
--
F
E
I
--------
G
-
C
P
V
L
G
I
C
Y
G
M
Q
T
M
A
Y
Q
L
G
G
K
V
N
------
E
F
G
H
A
-
Q
L
R
---
V
-----------------------------
L
---
N
P
A
F--
L
F
D
G
I
EDQVS
P
Q
--------
G
E
P
L
L
D
V
W
M
S
H
G
D
I
V
--
S
E
L
-
P
--
P
G
F
-
E
A
T
A
C
-
T
-
D
N
S
P
-----
L
A
A
M
A
D
F
K
R
R
F
F
-
G
L
Q
F
H
P
E
V
T
H
T
P
Q
G
H
R
I
L
A
H
F
V
-----------