@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1916: (2016-03-30 )
MKDLTMLLDELKDMSFFNKGDICLIGCSTSEVIGEKIGTVGSMEVAETIFNALDVVSKETGVTFAFQGCEHINRAITIEKSQYNPLTMEEVSVVPDVHAGGSLATYAFQHMKDPIVVEHITVPCGIDIGQTLIGMHIKHVCVPVRTSVKQVGQAIVTIATSRPKKIGGERAKYK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-------.......--20---......------..30.-.......40..-----......-50....----.----...60....-..-..70------..-....--..80----......--...90........100---.---........110...-....120.--...--...----..130.......-140.......150--....-...160.......170..----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK
D
L
T
M
L
L
D
E
L
K
-------
D
MSFFNK--G
D
---
I
C
L
I
GC------
S
T
S
E
V
-
I
G
E
K
IGTVG
S
M
-----
E
V
A
E
T
I
-
F
N
A
L
D
V
----
V
----SKET
G
V
T
F
A
-
F
Q
-
G
C
E
H------IN-
R
A
I
T
--
I
EK-----SQYNPL--
T
M
E
E
V
S
VVPDVHAG-----G---
S
L
A
T
Y
A
F
Q
HMKD
P
I
-
V
V
E
H
I--T--VPC--G
I
D
----
I
G
Q
T
L
I
G
M
H
I
K
H
-VC
V
P
V
R
T
S
V
K
Q
V
G
--
Q
A
I
V
-TIATSR
P
K
KIGGERAKYK----------------------------------
23
Fugue
99.59
40%
-139
* C2 *
1V8D
2
Y214_THET2 (first)
A:
[40-232]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
E
G
I
R
R
A
A
Q
R
A
A
E
E
F
L
-------
Q
A
F
P
M
A
P
--
G
S
---
L
F
V
L
G
G
------
S
T
S
E
V
-
L
G
----
T
R
P
S
L
-----
E
A
A
H
A
V
-
L
E
G
L
L
P
----
P
----
L
L
E
R
G
V
H
V
A
-
V
Q
-
A
C
E
H
------
L
N
-
R
A
L
V
--
V
E
R
-----
E
T
A
R
A
F
--
G
K
E
E
V
A
V
F
P
H
P
K
A
G
-----
G
---
A
K
A
T
A
A
F
L
R
F
R
D
P
V
-
M
V
E
S
L
--
K
AQ
A
H
G
--
G
M
D
----
I
G
G
V
L
I
G
M
H
L
R
P
-
V
A
V
P
L
R
L
S
V
R
K
I
G
--
E
A
V
L
-
L
A
A
K
T
R
P
K
L
V
G
G
A
R
A
V
Y
T
R
E
E
M
L
K
K
L
E
E
F
LP---------------------
2
HHSearch
98.12
40%
-136
- C2 -
1V8D
2
Y214_THET2 (first)
A:
[44-219]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
A
A
Q
R
A
A
E
E
F
L
-------
Q
A
F
P
M
A
P
--
G
S
---
L
F
V
L
G
G
------
S
T
S
E
V
-
L
----
G
T
R
P
S
L
-----
E
A
A
H
A
V
-
L
E
G
L
L
P
----
P
----
L
L
E
R
G
V
H
V
A
-
V
Q
-
A
C
E
H
------
L
N
-
R
A
L
V
--
V
E
R
-----
E
T
A
R
A
F
--
G
K
E
E
V
A
V
F
P
H
P
K
A
G
-----
G
---
A
K
A
T
A
A
F
L
R
F
R
D
P
V
-
M
V
E
S
L
KA
Q
--
A
H
G
--
G
M
D
----
I
G
G
V
L
I
G
M
H
L
R
P
-
V
A
V
P
L
R
L
S
V
R
K
I
G
--
E
A
V
L
-
L
A
A
K
T
R
P
K
L
V
G
G
A
R
A
V
Y
T
----------------------------------
1
PsiBlast_PDB
91.59
44%
-131
- C2 -
1V8D
2
Y214_THET2 (first)
A:
[63-218]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
---
L
F
V
L
G
G
------
S
T
S
E
V
-
L
----
G
T
R
P
S
L
-----
E
A
A
H
A
V
-
L
E
G
L
L
P
----
P
----
L
L
E
R
G
V
H
V
A
-
V
Q
-
A
C
E
H
------
L
N
-
R
A
L
V
--
V
E
R
-----
E
T
A
R
A
F
--
G
K
E
E
V
A
V
F
P
H
P
K
A
G
-----
G
---
A
K
A
T
A
A
F
L
R
F
R
D
P
V
-
M
V
E
S
L
--
K
--
A
Q
A
H
G
G
M
D
----
I
G
G
V
L
I
G
M
H
L
R
P
-
V
A
V
P
L
R
L
S
V
R
K
I
G
--
E
A
V
L
-
L
A
A
K
T
R
P
K
L
V
G
G
A
R
A
V
Y
-----------------------------------
28
Fugue
53.86
13%
-48
- C1 -
3Q9D
-
Y803_CHLPN
A:
[8-182]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
L
E
D
--
N
V
---
F
L
L
L
E
G
------
N
L
K
R
I
-
F
A
T
P
I
G
Y
T
T
F
R
-----
E
F
Q
N
V
V
-
F
N
C
A
N
----------
G
Q
Q
E
I
A
N
F
F
-
F
E
-
M
L
I
N
GKLT
Q
E
L
A
-
P
Q
Q
K
--
Q
A
A
-----
H
S
L
I
A
E
--
F
M
M
P
I
R
V
A
K
D
I
H
E
R
-----
G
---
E
F
I
N
F
I
T
S
D
M
L
T
Q
Q
E
R
C
I
F
L
--
N
--
R
L
A
--
R
V
D
----
G
Q
E
F
L
L
M
T
D
V
Q
N
-
T
C
H
L
I
R
H
L
L
A
R
L
L
--
E
A
Q
K
N
P
V
G
E
K
N
L
Q
E
I
Q
E
E
I
T
S
L
K
N
H
F
D
E
L
T
K
A-------------------------
29
Fugue
48.48
18%
-67
- C1 -
2PNN
1
TRPV1_RAT
A:
[11-258]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYD
R
R
S
I
F
D
A
V
A
Q
SN
C
Q
E
L
E
S
L
L
P
F
L
Q
R
S
KKRLT
D
S
E
F
K
D
P
ET
G
K
---
T
C
L
L
K
A
M
L
N
LHN
G
Q
N
D
T
-
I
A
L
L
L
D
V
A
R
K
T
-----
D
S
L
K
Q
F
-
V
N
A
S
Y
T
----
D
----
S
Y
Y
K
G
Q
T
A
L
-
H
I
-
A
I
E
R
------
R
N
M
T
L
V
T
L
L
V
E
N
GADVQ
A
A
A
N
G
D
--
F
F
K
K
T
K
G
R
P
G
F
Y
F
G
-----
E
L
P
L
S
L
A
A
C
T
N
Q
L
A
I
V
K
F
-
L
L
Q
N
S
--
W
--
Q
P
A
--
D
I
S
ARDS
V
G
N
T
V
L
H
A
L
V
E
V
-
A
D
N
T
V
D
N
T
K
F
V
T
S
M
Y
N
E
I
L
-
I
L
G
A
K
L
H
P
T
L
K
L
E
E
I
T
N
R
KGLT
P
L
A
L
A
A
S
S
GK
I
G
V
L
A
Y
I
L
Q
R
E
I
H-------
27
Fugue
41.50
12%
-40
- C1 -
4RFS
-
?
S:
[3-200]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R
H
K
T
F
R
L
V
V
D
A
L
L
-------
M
A
I
V
L
L
Q
--
N
L
---
V
P
F
L
G
Y
------
I
P
F
G
P
-
F
S
M
T
L
------------
I
G
L
T
V
-
I
V
A
G
S
A
----
L
----
G
P
R
D
G
L
L
I
G
-
G
F
W
G
L
I
T
------
F
V
-
R
A
F
T
--
W
P
S
-----
S
P
V
A
P
L
IF
T
N
P
L
I
S
I
L
P
R
L
L
M
G
---------
L
V
A
G
S
L
Y
L
W
G
R
H
R
Q
-
W
S
M
R
Q
--
A
--
M
Q
V
--
A
A
G
----
C
A
A
L
T
N
T
V
L
V
L
G
-
L
V
F
L
F
Y
Q
T
P
A
V
L
G
--
Y
V
L
M
-
I
S
L
F
T
N
G
I
P
E
L
I
L
D
V
L
V
A
PLIAMPLRRQWERLKPQ-----------------
10
HHSearch
39.57
12%
-103
- C2 -
3P45
-
CASP6_HUMAN
A:
[94-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
L
L
K
I
H
E
V
S
-------
T
V
-
S
H
A
D
--
A
D
---
C
F
V
C
V
F
------
L
S
H
G
E
-
G
N
H
I
Y
A
Y
D
A
K
I
-----
E
I
-
Q
T
L
-
T
G
L
F
K
G
DKCH
S
----
L
V
G
K
P
K
I
F
I
-
I
Q
-
A
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
38.47
15%
-37
- C1 -
4CR2
-
PSA5_YEAST (first)
S:
[126-478]
K
T
I
E
V
T
A
E
I
N
C
F
M
H
L
L
V
Q
L
F
L
WDSKELEQL
V
E
F
N
R
K
V
V
I
P
N
L
L
C
Y
YNLRSLNLINA
K
L
W
F
Y
I
Y
L
S
H
E
T
LARSSEEINSD
N
Q
N
I
I
L
R
S
T
M
M
K
F
L
K
I
ASLKHD
N
E
T
K
A
M
L
I
N
L
I
L
R
D
F
L
N
NGEVDSA
S
D
F
I
S
K
L
EYPHTDVS
S
S
L
E
A
R
Y
F
F
Y
L
S
K
I
N
A
I
Q
LD
Y
S
T
A
N
E
Y
I
I
A
A
I
RKAPH
N
S
K
S
L
G
F
L
Q
Q
S
N
K
L
H
C
C
I
Q
L
L
M
G
D
I
P
-------
E
L
S
F
F
H
Q
--
S
N
---
M
-
Q
K
S
L
------
L
P
Y
Y
H
-
L
T
K
A
V
K
L
G
D
L
K
-----
K
F
T
S
T
I
-
T
K
Y
K
Q
L
----
L
----
L
K
D
D
----
T
-
Y
Q
-
L
C
V
R
------
L
R
-
S
N
V
I
--
K
T
G
-----
I
R
I
I
S
L
--
T
Y
K
K
I
S
------------------
L
R
D
I
C
L
K
L
N
L
D
S
E
-
Q
T
V
E
Y
--
M
--
V
S
R
--
A
I
R
----
D
G
--
V
I
E
A
K
I
N
H
------
E
D
G
F
I
E
T
T
--
E
L
L
N
-
I
Y
D
S
E
D
P
Q
Q
V
F
D
E
R
I
K
F
A
N
Q
L
H
D
E
Y
L
V
S------------------------
14
HHSearch
37.11
17%
-69
- C2 -
1PYO
1
CASP2_HUMAN
A:
[83-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
M
Q
E
K
L
Q
N
F
A
-------
Q
L
P
A
H
R
V
--
T
D
---
S
C
I
V
A
L
------
L
S
H
G
V
-
E
G
A
I
Y
G
V
D
G
K
L
-----
L
Q
L
Q
E
V
-
F
Q
L
F
D
N
----
A
NCPS
L
Q
N
K
P
K
M
F
F
-
I
Q
-
A
C
R
G
------
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
34.37
16%
-52
- C2 -
3E4C
-
?
A:
[107-198]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
M
T
T
E
L
E
A
F
A
-------
H
R
P
E
H
K
T
--
S
D
---
S
T
F
L
V
F
------
M
S
H
G
I
-
R
E
G
I
C
G
K
K
H
S
E
Q
V
P
D
I
L
Q
L
N
A
I
-
F
N
M
L
N
T
----
K
NCPS
L
K
D
K
P
K
V
I
I
-
I
Q
-
A
A
R
G
------
D
S
-
P
G
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
33.93
27%
-35
- C2 -
3IJW
2
?
A:
[19-67]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
T
N
D
L
-------
R
K
L
G
L
K
K
--
G
M
---
T
V
I
V
H
S
------
S
L
S
S
--
I
G
W
I
S
G
G
-----------
A
V
A
V
-
V
E
A
L
M
E
----
V
----
I
T
E
E
G
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
33.62
13%
-16
- C1 -
4I17
4
?
A:
[4-226]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTD
P
N
Q
L
K
N
E
G
N
D
A
L
N
A
K
N
Y
A
V
A
F
E
K
Y
S
-------
E
Y
L
K
L
T
N
--
N
Q
D
S
V
T
A
Y
N
C
G
------
V
C
A
D
N
-
I
K
K
Y
K
E
A
A
D
Y
F
-----
D
I
A
I
K
K
N
Y
N
L
A
N
A
----
Y
----
I
G
K
S
A
A
Y
R
D
M
K
N
-
N
Q
E
Y
------
I
A
-
T
L
T
E
--
G
I
K
-----
A
V
P
G
N
A
--
T
I
E
K
L
Y
A
I
Y
Y
L
K
E
G
-----
Q
---
K
F
Q
Q
-
A
G
N
I
E
K
A
E
E
-
N
Y
K
H
A
--
T
---------
D
----
V
T
S
K
K
W
K
T
D
A
L
Y
S
L
G
V
L
F
Y
N
N
G
A
D
V
L
--
R
K
A
T
-
P
L
A
S
S
N
K
E
K
Y
A
S
E
K
A
K
A
D
A
A
F
K
K
A
V
D
Y
L
G
E
A
V
T
L
S
PNR
T
E
I
K
Q
M
Q
D
Q
V
K
A
M
I
22
HHSearch
32.18
20%
-59
- C2 -
3J7Y
-
RM18_HUMAN
P:
[97-141]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
---
K
V
V
V
S
A
------
S
T
R
E
W
A
I
K
K
H
-----
N
V
-----
V
A
C
E
S
I
-
G
R
V
L
A
Q
----
R
----
C
L
E
A
G
I
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
31.92
18%
-15
- C2 -
2YNM
4
CHLB_PROMA
D:
[72-145]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
K
G
H
I
F
E
A
V
-------
E
--
R
F
K
P
--
E
A
---
L
L
V
G
E
S
------
C
T
A
E
L
-
I
Q
D
Q
P
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
31.09
22%
-42
- C2 -
3SMA
1
?
A:
[26-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
A
S
D
L
-------
A
A
L
G
V
R
P
--
G
G
---
V
L
L
V
H
A
------
S
L
S
A
L
--
G
W
V
C
G
G
-----------
A
Q
A
V
-
V
L
A
L
Q
D
----
A
----
V
G
K
E
G
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
30.94
27%
-32
- C2 -
2NYG
1
YOKD_BACSU
A:
[16-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
S
I
T
E
D
L
-------
K
A
L
G
L
K
K
--
G
M
---
T
V
L
V
H
S
------
S
L
S
S
I
--
G
W
V
N
G
G
-----------
A
V
A
V
-
I
Q
A
L
I
D
----
V
----
V
T
E
E
G
T
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
30.14
16%
-29
* C1 *
4MYZ
-
?
A:
[9-75]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
T
E
L
S
E
I
-----
E
L
E
A
S
V
-
L
Q
E
I
E
A
----
L
----
E
K
L
I
S
L
S
---------
A
------
L
Q
-
R
A
L
I
--
A
L
K
-----
D
A
R
S
K
L
--
E
K
Y
E
---------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
27.50
13%
18
- C2 -
2Q0Y
4
?
A:
[103-149]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
G
Q
A
L
-
M
N
R
A
E
A
----
E
----
F
A
E
R
G
I
A
F
A
-
V
L
-
H
A
---------
T
-
E
-----
M
G
Q
-----
P
L
Y
A
R
M
--
G
W
S
P
T
T
E
M
S
K
---------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
26.84
15%
-42
- C2 -
2OKG
2
CGGR_BACSU
A:
[7-75]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
G
L
T
L
--
L
E
K
-----
T
L
K
E
R
L
--
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
SPW
V
K
K
---
E
M
G
R
A
A
V
A
C
M
K
K
R
F
---
S
G
---
K
--
N
I
V
--
A
V
T
----
G
G
T
T
I
E
A
V
A
----------------------------------------------------------------------------
13
HHSearch
26.73
22%
-2
- C2 -
3PDI
-
?
B:
[78-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
V
V
E
A
L
K
T
I
C
-------
E
--
R
Q
N
P
--
S
V
---
I
G
L
L
T
T
------
G
L
S
E
T
-
Q
G
C
D
L
H
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------