@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1918: (2016-03-30 )
MDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIVHIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------.........10........20....---...-.30........40........50...-.-....60........70........80--..-.-..--....90........100--.......110---....-----------.-..120.----......130.......140.......150.....-..160.......170....-.-..180..--------------......190...--------------....200....----...210.......220.......230.......240.......250.....--..260.......270...-....280........----.290.......300.......310.......320.......330.......340......---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------MDTKI
W
D
V
R
E
Y
N
E
D
L
Q
QYPK
I
N
E
I
K
---
D
I
V-LNGGLIGLPTE
T
V
Y
GLAANAT
D
E
E
A
V
-
A
-
K
I
Y
E
AKGRPSDN
P
L
I
V
H
IH
S
K
V
Q
L
K
---
D
F
-
T
-
Y
T--L
D
P
R
V
E
K
L
M
Q
A
FWPG
P
I
--
S
F
I
L
PLKP
G
Y
---
L
C
R
K
-----------V-SGG
L
S
S
----
V
A
V
RMP
S
H
S
V
G
R
Q
L
L
Q
I
I
NEPLAAPSANLSGRPS-P
T
T
F
N
H
V
Y
Q
D
L
N
A
RID
G
I
V
-Q-
A
E
Q
S-EE--------------
G
L
E
S
T
V
L
DCTSF--------------PYKIARPG
S
I
T
----
A
A
M
I
T
E
IL
P
N
S
IAHADYNDTEQPIAPGMKYKHYSPNT
P
L
T
I
I
T
D
I
E
S
KIGN--DGKDW
S
S
I
A
F
I
VPS
N
K
V
A
-FIPS
E
--
A
Q
F
I
Q
L
CQ----DDN
D
V
K
Q
A
S
H
N
L
Y
D
V
L
H
SLDENEN
I
S
A
A
Y
I
Y
G
F
ELND
N
T
E
A
I
M
N
R
M
L
K
A
AGNHIIKGCEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
96.26
38%
-94
- C6 -
2EQA
2
SUA5_SULTO
A:
[11-342]
-------------------------------------------------------------------------------------------------
N
P
E
I
D
K
I
K
I
A
A
---
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
-
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
I
A
D
F
N
Q
L
F
---
E
V
-
A
-
K
D
--
I
P
D
K
V
L
E
I
A
Q
I
V
W
P
G
P
L
--
T
F
V
L
K
K
T
E
-
R
---
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
I
A
A
P
S
A
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
-
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
----
I
E
E
L
K
K
L
F
G
E
I
V
I
----------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
R
N
I
F
K
D
V
V
S
L
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
L
S
K
-
E
F
E
G
L
--
Q
-
Q
I
I
L
G
-----
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
L
-
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
F
S
I
I
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.05
40%
-87
- C6 -
3AJE
8
SUA5_SULTO
A:
[12-343]
-----------------------------------------------------------------------------------------------------
P
E
I
D
K
I
K
I
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
-
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
I
A
D
F
N
Q
L
F
---
E
V
-
A
-
K
D
--
I
P
D
K
V
L
E
I
A
Q
I
V
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
---
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
I
A
A
P
S
A
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
-
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
P
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
I
V
I
P
---------------------
H
Y
A
P
N
T
R
L
L
L
V
E
N
-----
R
N
--
I
F
K
D
V
V
S
L
--
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
LS
K
E
F
E
G
L
Q
Q
I
I
LG
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
-
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
F
S
I
I
K
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.81
39%
-91
- C6 -
2EQA
2
SUA5_SULTO
A:
[12-343]
-----------------------------------------------------------------------------------------------------
P
E
I
D
K
I
K
I
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
-
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
I
A
D
F
N
Q
L
F
---
E
V
-
A
-
K
D
--
I
P
D
K
V
L
E
I
A
Q
I
V
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
---
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
I
A
A
P
S
A
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
-
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
I
V
I
--------------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
-----
R
N
--
I
F
K
D
V
V
S
L
--
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
LS
K
E
F
E
G
L
Q
Q
I
I
LG
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
-
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
F
S
I
I
K
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
95.68
39%
-92
- C6 -
4E1B
2
SUA5_SULTO
A:
[12-343]
-----------------------------------------------------------------------------------------------------
P
E
I
D
K
I
K
I
A
A
D
V
I
-
R
N
G
G
T
V
A
F
P
T
E
T
V
Y
G
L
G
A
N
A
F
D
G
N
A
C
-
L
-
K
I
F
Q
A
K
N
R
P
V
D
N
P
L
I
V
H
I
A
D
F
N
Q
L
F
---
E
V
-
A
-
K
D
--
I
P
D
K
V
L
E
I
A
Q
I
V
W
P
G
P
L
--
T
F
V
L
K
-
K
T
E
R
---
V
P
K
E
-----------
V
-
T
A
G
L
D
T
----
V
A
V
R
M
P
A
H
P
I
A
L
Q
L
I
R
E
S
G
V
P
I
A
A
P
S
A
N
L
A
T
R
P
S
-
P
T
K
A
E
D
V
I
V
D
L
N
G
R
V
D
V
I
I
-
D
-
G
G
H
T
-
F
F
--------------
G
V
E
S
T
I
I
N
V
T
V
E
--------------
P
-
V
L
L
R
P
G
P
F
T
I
E
E
L
K
K
L
F
G
E
I
V
I
--------------------
Y
K
H
Y
A
P
N
T
R
L
L
L
V
E
N
-----
R
N
--
I
F
K
D
V
V
S
L
--
L
S
K
K
Y
K
V
A
L
L
I
P
K
E
LS
K
E
F
E
G
L
Q
Q
I
I
LG
S
D
E
N
L
Y
E
V
A
R
N
L
F
D
S
F
R
E
L
D
K
-
L
N
V
D
L
G
I
M
I
G
F
P
E
R
G
I
G
F
A
I
M
N
R
A
R
K
A
S
G
F
S
I
I
K
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
69.30
30%
-92
- C6 -
1HRU
1
TSAC_ECOLI
A:
[5-188]
--------------------------------------------------------------------------------------------------
L
Q
R
D
A
I
A
A
A
I
---
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
-
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
A
A
N
Y
E
Q
L
K
---
P
Y
-
I
-
D
D
TM
L
T
D
V
Q
R
E
T
I
F
S
R
W
P
G
P
V
--
T
F
V
F
P
A
P
A
-
T
---
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
L
V
S
T
S
A
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
-
V
V
-
P
-
G
E
T
G
-
G
R
--------------
L
N
P
S
E
I
R
D
A
L
T
G
----------------
E
L
F
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
69.08
19%
-66
- C6 -
3TTC
6
?
A:
[12-657]
QIVPDAATC
P
A
C
L
A
E
M
N
TPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAA
F
P
L
C
P
A
C
D
K
E
Y
R
DPLDRRFHAQPVACPE
C
G
P
Y
L
E
-
W
V
S
H
G
E
H
A
E
Q
E
A
A
L
Q
A
A
I
---
A
Q
L
-
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
M
L
P
V
A
D
G
L
--------------
P
D
A
A
R
Q
L
L
T
T
P
-
A
A
P
I
--
V
L
V
D
K
K
Y
V
P
E
---
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
-
I
-
H
N
R
D
I
V
Q
--------------
R
M
D
D
S
V
V
R
E
S
G
E
--------------
M
L
R
R
S
R
-
G
Y
V
P
----
D
A
L
A
--------
L
P
P
G
F
K
N
V
P
P
V
L
C
L
G
A
D
L
K
N
-----------------------------
T
F
C
L
V
R
G
E
Q
V
-
V
L
-------------------------
S
Q
H
L
G
D
L
-----
S
D
D
G
I
-------
Q
T
Q
W
R
E
A
L
R
L
M
Q
N
I
Y
N
F
T
P
Q
Y
V
V
H
D
A
H
P
GY
V
S
C
Q
W
A
S
E
MN
L
P
T
Q
T
V
L
H
H
H
A
H
A
A
A
C
L
A
E
H
QWPLDG
G
D
V
I
A
L
T
L
D
G
I
G
M
G
E
NG
A
L
W
G
GECLRVNYR
E
C
E
H
L
G
GLPAVALPG
G
D
L
A
A
K
Q
P
W
R
N
L
L
A
Q
C
L
R
FVPEWQNYPET
A
S
V
A
A
ANW
S
V
L
A
R
A
I
E
R
GIN
A
P
L
A
SS
C
G
R
L
F
D
A
V
A
A
A
L
GCAPATLSYEG
E
A
A
C
A
L
E
A
L
A
A
S
CD
G
V
T
H
PVTMPRVDNQLD
L
A
T
F
W
Q
Q
W
L
N
WQAP
V
N
Q
R
A
W
A
F
H
D
A
L
A
Q
G
F
A
A
L
M
R
E
Q
A
T
M
R
GIT
T
L
V
F
S
G
GVIHN
R
L
L
R
A
R
L
A
H
Y
L
AD
F
T
L
L
F
P
Q
SLPAGDGG
L
S
L
G
Q
G
V
I
A
A
A
R
W
L
A
GE
32
Fugue
67.57
30%
-91
- C6 -
1HRU
1
TSAC_ECOLI
A:
[3-188]
------------------------------------------------------------------------------------------------
N
N
L
Q
R
D
A
I
A
A
A
I
---
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
--
M
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
A
A
N
Y
E
Q
L
K
---
P
Y
I
D
-
D
T
M-
L
T
D
V
Q
R
E
T
I
F
S
R
W
P
G
P
V
--
T
F
V
F
P
A
P
A
T
----
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
L
V
S
T
S
A
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
-
V
V
-
P
-
G
E
T
G
-
G
R
--------------
L
N
P
S
E
I
R
D
A
L
T
G
--------------
E
L
F
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
65.46
29%
-86
- C6 -
1HRU
1
TSAC_ECOLI
A:
[3-188]
------------------------------------------------------------------------------------------------
N
N
L
Q
R
D
A
I
A
A
A
I
---
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
M
R
-
L
L
E
L
K
-
Q
R
P
V
D
K
G
L
I
L
I
A
A
N
Y
E
Q
L
K
---
P
Y
-
I
D
D
T
M-
L
T
D
V
Q
R
E
T
I
F
S
R
W
P
G
P
V
--
T
F
V
F
P
A
P
A
T
----
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
L
V
S
T
S
A
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
F
G
A
A
F
P
-
V
V
-
P
-
G
E
T
G
-
G
R
--------------
L
N
P
S
E
I
R
D
A
L
----------------
T
G
E
L
F
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
64.87
24%
-98
- C6 -
1K7J
1
YCIO_ECOLI
A:
[9-205]
-----------------------------------------------------------------------------------------------
P
D
N
P
Q
Q
R
L
I
N
Q
A
V
---
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
-
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
C
R
D
L
S
E
L
S
---
T
Y
-
S
-
F
---
V
D
N
V
A
F
R
L
M
K
N
N
T
P
G
N
Y
--
T
F
I
L
K
G
T
K
-
E
---
V
P
R
R
-----------
L
L
Q
E
K
R
K
T
----
I
G
M
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
M
L
S
T
S
L
M
L
P
G
S
E
F
T
E
S
D
P
E
E
I
K
D
R
L
E
K
Q
V
D
L
I
I
-
H
-
G
G
Y
L
--
G
--------------
Q
K
P
T
T
V
I
D
L
T
D
D
--------------
T
P
V
V
V
R
E
G
V
G
D
----
V
K
P
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
63.97
30%
-76
- C6 -
1JCU
-
?
A:
[16-193]
-------------------------------------------------------------------------------------------------------
L
E
E
A
I
---
S
V
M
-
E
G
G
G
I
V
I
Y
P
T
D
T
I
Y
G
L
G
V
N
A
L
D
E
D
A
V
-
R
-
R
L
F
R
V
K
G
R
S
P
H
K
P
V
S
I
C
V
S
C
V
D
E
I
P
---
R
F
-
S
-
R
P
--
S
G
D
A
M
E
-
L
M
E
R
I
L
P
G
P
Y
--
T
V
V
L
E
-
R
N
E
L
---
I
P
D
V
-----------
I
-
T
G
G
S
S
R
----
V
G
I
R
V
P
D
D
E
I
C
R
R
I
A
A
--
R
F
P
V
T
A
T
S
A
N
I
S
G
K
P
P
-
S
P
R
L
E
E
I
V
R
D
L
D
A
-
V
D
L
V
L
-
D
-
A
G
D
C
-
L
D
--------------
M
E
P
S
T
V
I
D
L
T
V
N
--------------
P
P
R
V
L
R
R
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
62.93
20%
-77
* C6 *
3VTH
4
?
A:
[202-390]
----------------------------------------------------------------------------------------------------
D
D
E
I
K
C
V
A
---
K
A
L
-
K
E
G
K
I
V
A
I
K
G
I
G
G
F
H
L
A
V
N
A
L
D
D
E
A
V
-
A
-
T
L
R
R
R
K
K
R
Y
-
G
K
P
F
A
V
M
M
R
D
V
E
E
V
K
---
K
Y
-
C
-
I
---
V
S
P
E
E
E
R
L
L
L
S
-
Q
R
R
P
I
--
V
L
L
K
K
K
G
E
-
K
---
L
A
K
G
-----------
I
-
A
D
D
L
D
T
----
L
G
V
M
L
P
Y
A
P
I
H
Y
L
L
M
E
E
I
D
F
P
I
V
M
T
S
G
N
V
S
E
E
P
I
-
C
K
D
N
E
E
A
L
E
K
L
K
D
I
A
D
V
F
L
-
L
N
N
R
D
I
-
V
N
--------------
R
I
D
D
S
V
T
S
F
N
A
G
--------------
A
E
R
I
I
R
R
A
R
G
Y
----
A
P
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
62.41
23%
-73
- C6 -
3TTC
2
?
A:
[111-292]
----------------------------------------------------------------------------------------------------
E
A
A
L
Q
A
A
I
---
A
Q
L
-
K
M
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
-
A
K
P
L
A
V
M
L
P
V
A
D
G
L
P
--------------
D
A
A
R
Q
L
L
T
T
-
P
A
A
P
I
--
V
L
V
D
K
K
Y
V
P
E
---
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
I
H
-
N
R
D
I
-
V
Q
--------------
R
M
D
D
S
V
V
R
E
S
G
-----------------
E
M
L
R
R
S
R
G
Y
----
V
P
D
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
60.81
34%
-75
- C6 -
1HRU
1
TSAC_ECOLI
A:
[3-160]
-----------------------------------------------------------------------------------------------
N
N
L
Q
R
-
D
A
I
A
A
A
I
---
D
V
L
-
N
E
E
R
V
I
A
Y
P
T
E
A
V
F
G
V
G
C
D
P
D
S
E
T
A
V
-
M
-
R
L
L
E
L
K
Q
R
P
V
D
K
G
L
I
L
I
A
A
N
Y
E
Q
L
K
PYI
D
D
-
T
-
M
L
--
T
D
V
Q
R
E
T
I
F
S
R
-
W
P
G
P
V
--
T
F
V
F
P
-
A
P
A
T
---
T
P
R
W
-----------
L
-
T
G
R
F
D
S
----
L
A
V
R
V
T
D
H
P
L
V
V
A
L
C
Q
A
Y
G
K
P
L
V
S
T
S
A
N
L
S
G
L
P
P
-
C
R
T
V
D
E
V
R
A
Q
F
G
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
60.75
27%
-101
- C6 -
3TTC
2
?
A:
[124-260]
---------------------------------------------------------------------------------------------------------------------
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
M
L
P
V
A
D
G
L
P
---
D
-----------
A
A
R
Q
L
L
T
T
----
P
A
--
A
P
I
V
L
V
D
K
K
Y
VPE
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
60.39
27%
-99
- C6 -
3TTD
1
?
A:
[124-260]
---------------------------------------------------------------------------------------------------------------------
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
M
L
P
V
A
D
G
L
P
---
D
-----------
A
A
R
Q
L
L
T
T
----
P
A
--
A
P
I
V
L
V
D
K
K
Y
VPE
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
60.29
27%
-100
- C6 -
3TSQ
2
?
A:
[124-260]
---------------------------------------------------------------------------------------------------------------------
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
M
L
P
V
A
D
G
L
P
---
D
-----------
A
A
R
Q
L
L
T
T
----
P
A
--
A
P
I
V
L
V
D
K
K
Y
VPE
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
60.00
27%
-101
- C6 -
3TSP
1
?
A:
[124-260]
---------------------------------------------------------------------------------------------------------------------
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
M
L
P
V
A
D
G
L
P
---
D
-----------
A
A
R
Q
L
L
T
T
----
P
A
--
A
P
I
V
L
V
D
K
K
Y
VPE
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
59.78
27%
-101
- C6 -
3TTF
1
?
A:
[124-260]
---------------------------------------------------------------------------------------------------------------------
G
N
I
V
A
I
K
G
I
G
G
F
H
L
A
C
D
A
R
N
S
N
A
V
-
A
-
T
L
R
A
R
K
H
R
P
A
-
K
P
L
A
V
M
L
P
V
A
D
G
L
P
---
D
-----------
A
A
R
Q
L
L
T
T
----
P
A
--
A
P
I
V
L
V
D
K
K
Y
VPE
L
C
D
D
-----------
I
-
A
P
G
L
N
E
----
V
G
V
M
L
P
A
N
P
L
Q
H
L
L
L
Q
E
L
Q
C
P
L
V
M
T
S
G
N
L
S
G
K
P
P
-
A
I
S
N
E
Q
A
L
E
D
L
Q
G
I
A
D
G
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
58.89
21%
-82
- C6 -
3L7V
7
?
A:
[42-283]
---------------------------------------------------------------------------------------------------
D
G
N
L
S
Q
E
G
F
---
E
I
V
K
G
E
G
G
V
I
V
C
P
T
K
V
G
Y
I
I
M
T
--
S
D
K
K
G
L
-
E
-
R
K
F
E
A
K
K
R
N
R
N
K
P
G
V
V
L
C
G
S
M
E
E
L
R
---
A
L
-
A
-
Q
---
L
T
P
E
I
D
A
F
Y
Q
K
H
W
D
E
D
I
L
L
G
C
I
L
P
W
K
A
-
E
---
A
Y
E
K
L
K
AYGDGREEL
M
-
T
D
I
R
G
T
S
C
F
V
I
K
F
G
V
A
G
E
Q
I
A
K
E
M
W
E
K
E
G
R
M
V
Y
A
S
S
A
N
-----
N
-
R
G
K
V
E
G
I
G
E
R
I
E
S
M
V
D
L
V
I
-
E
-
A
D
D
Y
-
V
A
S
I
Q
PDKTIETRYE
Q
G
V
M
V
S
M
V
D
K
D
G
K
L
I
P
QQGADSRSVEP
C
P
V
V
I
R
K
G
L
-
D
----
I
D
K
I
M
M
H
L
S
D
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
57.57
25%
-98
- C6 -
1KK9
1
YCIO_ECOLI
A:
[32-164]
-------------------------------------------------------------------------------------------------------
I
N
Q
A
V
---
E
I
V
-
R
K
G
G
V
I
V
Y
P
T
D
S
G
Y
A
L
G
C
K
I
E
D
K
N
A
M
-
E
-
R
I
C
R
I
R
Q
L
P
D
G
H
N
F
T
L
M
C
R
D
L
S
E
L
S
---
T
Y
-
S
-
F
---
V
D
N
V
A
F
R
L
M
K
N
N
T
P
G
N
Y
--
T
F
I
L
K
G
T
K
E
V
---
P
R
R
L
-----------
L
-
Q
E
K
R
K
T
----
I
G
M
R
V
P
S
N
P
I
A
Q
A
L
L
E
A
L
G
E
P
M
L
S
T
S
L
M
L
P
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------