@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0971: (2015-12-19 )
MKKGSLAIVLGSLLASGTFYTALADGMPMKQQHNNMGESVELHFHYPIKGKQEPKNNHLVVLIDPKIEANKVIPENYQKEFEKSLFLQLSNFLERKGYSVSQFKDVSEIPQDIKEKALLVLRMDGNVAILEDIVEESDALSEEKVIDMSSGYLNLNFVEPKSEDIIHSFGIDVSKIKAVIERVELRRTNSGGFVPKTFVHRIKETDHDRAIKKIMNQAYHKVMAHITKELSKKHMERYEKVSSEMKKRK
Atome Classification :
(20 SA)
-------------------------------------.........10-.......----..20........30.......--.40----.....-...50...-...---..60---.....-....70........80........90...----.....100....--...110........120--.........130.---..---..------..140.---.-.--....150.......160.....-..170.--.---......180..----.....190.-......-200.......210....------...220.......230.......240.......-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------MKKG
S
L
A
I
V
L
--
G
S
L
L
ASG----
T
F
Y
T
A
LADGMP
M
K
Q
Q
HNNMG
E
--
S
V
E
----
L
H
F
H
Y-PIKGKQEP-KNN---
H
L
V
----
V
L
IDP-KIEANKVI
P
E
N
Y
Q
K
E
F
E
K
S
L
F
L
Q
L
S
N
F
L
E
----RKGY
S
V
S
Q
F
K
D
V
--
S
E
I
P
-
Q
D
I
K
EK
A
L
L
V
----
L
RMDG
N
V
A
I
L
E
D
I
---
V
E
---
E
S
------DALSEE---
K
-
V
--
I
DMSS
G
Y
L
N
L
N
F
VEPKSE
D
I
I
H
-
S
FG-I
D
--
V
---
S
K
I
K
A
V
I
E
R
V
E
----LRRTNSGGF-V
P
K
T
F
V
-
H
R
I
KET
D
H
D
R
A
I
K
K
I
M
N
------
Q
A
Y
H
K
V
M
A
H
I
T
K
E
L
S
K
K
H
M
E
R
Y
E
K
V
S
S
E
M
KKRK-----------------------
4
PsiBlast_CBE
92.50
94%
-112
- C5 -
3BGH
2
?
B:
[21-221]
------------------------------------------------------------------------------------------
L
H
F
H
Y
-
P
I
K
G
K
Q
E
P
-
K
N
S
---
H
L
V
----
V
L
I
E
P
-
K
I
E
I
N
K
V
I
P
E
S
Y
Q
K
E
F
E
K
S
L
F
L
Q
L
S
S
F
L
E
----
R
K
G
Y
S
V
S
Q
F
K
D
A
--
S
E
I
P
-
Q
D
I
K
E
K
A
L
L
V
----
L
R
M
D
G
N
V
A
I
L
E
D
I
---
V
E
---
E
S
------
D
A
L
S
E
E
---
K
-
V
--
I
D
M
S
S
G
Y
L
N
L
N
F
V
E
P
K
S
E
D
I
I
H
-
S
F
G
-
I
D
--
V
---
S
K
I
K
A
V
I
E
R
V
E
---------------------
H
R
I
K
E
T
D
H
D
Q
A
I
R
K
I
M
N
------
Q
A
Y
H
K
V
M
V
H
I
T
K
E
L
S
K
K
H
M
E
H
Y
E
K
V
S
------------------------------
1
PsiBlast_PDB
71.82
31%
-78
- C5 -
2I9I
-
?
A:
[51-268]
----------------------------------------------------------------------------
E
R
M
K
T
--
S
S
E
HVTP
L
D
F
N
Y
-
P
I
H
I
V
Q
A
P
-
Q
N
H
---
H
V
V
----
G
I
L
T
P
-
R
I
Q
V
S
D
N
L
-
K
P
Y
I
D
K
F
Q
D
A
L
I
N
Q
I
Q
T
I
F
E
----
K
R
G
Y
Q
V
L
R
F
Q
D
E
--
K
A
L
N
-
A
Q
D
K
R
K
I
F
S
V
----
L
D
L
K
G
W
V
G
I
L
E
D
L
K
M
N
L
K
---
D
P
------
N
N
P
N
L
D
---
T
-
L
--
V
D
Q
S
S
G
S
V
W
F
N
F
Y
E
P
E
S
N
R
V
V
H
-
D
F
A
-
V
E
--
V
---
G
T
F
Q
A
M
T
--
Y
T
----
Y
K
H
N
N
S
G
G
L
N
S
S
N
S
I
I
-
H
E
Y
L
E
K
N
K
E
D
A
I
H
K
I
L
N
------
R
M
Y
A
V
V
M
K
K
A
V
T
E
L
T
K
E
N
I
D
K
Y
R
E
A
I
D
R
M
K
G
F
K
-----------------------
15
Fugue
71.38
31%
-74
- C5 -
2I9I
-
?
A:
[51-271]
-------------------------------------------------------------------
E
R
M
K
T
S
S
E
H
-------
V
T
P
----
L
D
F
N
Y
-
P
I
H
I
V
Q
A
P
-
Q
N
H
---
H
V
V
----
G
I
L
T
P
-
R
I
Q
V
S
D
N
L
-
K
P
Y
I
D
K
F
Q
D
A
L
I
N
Q
I
Q
T
I
F
E
----
K
R
G
Y
Q
V
L
R
F
Q
D
E
--
K
A
L
N
-
A
Q
D
K
R
K
I
F
S
V
----
L
D
L
K
G
W
V
G
I
L
E
D
L
---
K
M
N
LK
D
P
------
N
N
P
N
L
D
---
T
-
L
--
V
D
Q
S
S
G
S
V
W
F
N
F
Y
E
P
E
S
N
R
V
V
H
-
D
F
A
-
V
E
--
V
---
G
T
F
Q
A
M
T
Y
T
Y
K
------
H
N
N
S
G
G
L
N
S
S
N
S
I
I
-
H
E
Y
L
E
K
N
K
E
D
A
I
H
K
I
L
N
------
R
M
Y
A
V
V
M
K
K
A
V
T
E
L
T
K
E
N
I
D
K
Y
R
E
A
I
D
R
M
K
G
F
K
-----------------------
6
HHSearch
69.23
31%
-72
- C5 -
2I9I
-
?
A:
[53-271]
--------------------------------------------------------------------------
M
K
T
S
S
E
H
--
V
T
P
----
L
D
F
N
Y
-
P
I
H
I
V
Q
A
P
-
Q
N
H
---
H
V
V
----
G
I
L
T
P
-
R
I
Q
V
S
D
N
L
-
K
P
Y
I
D
K
F
Q
D
A
L
I
N
Q
I
Q
T
I
F
E
----
K
R
G
Y
Q
V
L
R
F
Q
D
E
--
K
A
L
N
-
A
Q
D
K
R
K
I
F
S
V
----
L
D
L
K
G
W
V
G
I
L
E
D
L
---
K
M
N
LK
D
P
------
N
N
P
N
L
D
---
T
-
L
--
V
D
Q
S
S
G
S
V
W
F
N
F
Y
E
P
E
S
N
R
V
V
H
-
D
F
A
-
V
E
--
V
---
G
T
F
Q
A
M
T
Y
T
Y
K
----
H
--
N
N
S
G
G
L
-
N
S
S
N
S
I
I
H
E
Y
L
E
K
N
K
E
D
A
I
H
K
I
L
N
------
R
M
Y
A
V
V
M
K
K
A
V
T
E
L
T
K
E
N
I
D
K
Y
R
E
A
I
D
R
M
K
G
F
K
-----------------------
17
Fugue
48.09
13%
-31
- C4 -
1LVA
3
A:
[1-258]
----------------------------------------
G
S
P
E
K
I
L
--
A
Q
I
I
Q
E
H
----
R
------
E
G
L
D
W
Q
E
A
A
T
R
A
S
L
--
S
---------
L
E
-
E
T
R
K
L
L
Q
S
M
A
A
A
---
G
Q
V
----
T
L
L
R
V
-
E
-
N
D
L
Y
A
I
S
T
E
R
Y
Q
A
W
W
Q
A
V
T
R
A
L
E
E
F
H
S
R
Y
PL
R
P
G
L
A
R
E
E
L
R
S
R
YF
S
R
L
P
-
A
R
V
Y
Q
A
L
L
E
E
----
W
S
R
E
G
R
L
Q
L
A
A
N
T
---
V
A
---
L
A
G
F
T
P
S
F
S
E
T
Q
K
K
---
L
-
L
--
K
D
L
E
D
K
Y
R
V
S
R
W
Q
P
P
S
F
K
E
V
A
G
-
S
F
N
-
L
D
--
P
---
S
E
L
E
E
L
L
H
Y
L
V
R
E
GV
L
V
K
I
N
D
E
F
Y
-
W
H
R
Q
A
L
-
G
E
A
R
E
V
I
K
N
L
A
S
T
G
P
F
G
------
L
A
E
A
R
D
A
L
G
S
S
R
K
Y
V
L
P
L
L
E
Y
L
D
Q
V
K
F
T
R
R
V
G
D
K
R
V
V
VGN----------------
20
Fugue
41.90
12%
-39
- C4 -
3U61
4
DPA44_BPT4
C:
[5-323]
SMITVNEKEHILEQKYRPSTIDE
C
I
L
P
A
F
D
K
E
T
F
K
S
I
T
S
K
G
K
I
P
H
I
I
--
L
H
S
P
S
P
G
TG
K
T
T
V
A
K
A
L
C
H
D
V
N
A
D
M
M
F
V
N
G
S
D
--
C
K
I
----
D
F
V
R
G
-
P
L
T
N
F
A
S
A
-
A
S
F
DG
R
Q
K
V
----
I
V
I
D
----
E
F
D
R
S
G
L
A
E
S
Q
R
H
L
R
S
F
M
E
A
Y
S
S
N
---------
C
S
I
I
I
T
A
N
N
I
--
D
G
I
I
-
K
P
L
Q
S
R
C
R
V
I
T
F
GQ
P
T
D
E
D
K
I
E
M
M
K
Q
M
---
I
R
---
R
L
------
T
E
I
C
K
H
---
E
-
G
--
I
A
I
A
D
M
K
V
V
A
A
L
V
K
K
N
F
P
D
F
R
K
-
T
I
G
E
L
D
--
S
---
Y
S
S
K
G
V
L
D
A
G
I
----
L
S
L
V
T
N
D
R
G
-
A
I
D
D
V
L
-
E
S
L
K
N
K
D
V
K
Q
L
R
A
L
A
P
K
Y
AAD
Y
S
W
F
V
G
K
L
A
E
E
I
Y
S
R
V
T
P
Q
S
I
I
R
M
Y
E
I
V
G
E
N
N
Q
Y
H
GIAAN
T
E
L
H
L
A
Y
L
F
I
Q
L
A
C
E
MQW
23
Fugue
41.45
18%
-32
- C3 -
4YH8
2
?
A:
[15-194]
-------------------------------------
K
V
N
C
S
F
Y
Y
K
I
--
G
--------------
A
C
R
H
G
E
R
C
S
R
K
H
V
K
-------------------------
P
-
N
F
S
---
Q
T
I
----
L
C
--
P
-
N
M
Y
K
N
P
I
H
E
P
N
G
K
K
F
T
Q
R
E
L
A
E
Q
F
D
A
F
Y
E
----
D
M
F
C
E
F
S
K
Y
G
E
V
--
E
Q
L
V
V
C
D
N
V
G
D
H
L
V
---------
G
N
V
Y
V
R
F
K
Y
---
E
E
---
S
A
------
Q
N
A
I
D
D
L
N
S
R
-
W
--
Y
S
Q
R
P
V
Y
A
E
L
S
P
V
T
---------------------
D
F
R
E
A
C
C
R
Q
H
E
----
T
S
E
C
Q
R
G
G
L
-
C
--
N
F
M
-
H
A
----------------------------
K
K
P
S
P
Q
L
L
R
D
L
V
L
A
Q
R
K
Y
L
A
L
N
A
A
E
E
-----------------------
18
Fugue
39.75
14%
2
- C4 -
3KJH
1
?
A:
[1-254]
---------------------------M
K
L
A
V
A
G
K
GG
V
G
K
T
T
V
A
A
G
L
--
I
K
I
M
A
S
D
----
Y
D
K
I
Y
A
V
D
G
D
P
D
S
C
L
G
Q
T
L
G
L
--
S
I
E
----
E
A
Y
A
I
T
P
L
I
E
M
K
D
E
-
I
R
E
---
K
T
G
DGGL
L
I
L
N
P
-
K
V
D
G
D
---
L
D
K
Y
G
R
Y
I
D
D
K
I
F
L
I
R
M
G
E
I
K
----
K
G
G
------
S
Q
C
--
Y
C
R
E
-
N
S
F
L
G
S
V
V
S
A
----
L
F
L
D
K
K
E
A
V
V
M
D
M
---
G
A
---
G
I
------
E
H
L
T
R
G
---
T
-
A
K
A
V
D
M
M
I
A
V
I
E
P
N
L
N
S
I
K
T
G
L
N
I
E
-
K
L
A
-
G
D
L
G
I
---
K
K
V
R
Y
V
I
N
K
V
R
----
N
I
K
E
E
K
L
I
K
-
K
H
L
P
E
D
-
K
I
L
G
I
I
P
Y
N
E
L
F
I
E
L
S
L
------
K
G
------
E
E
I
W
Q
S
T
N
P
A
F
V
N
L
H
D
I
Y
Q
K
L
R
L
E
V
G----------------------
16
Fugue
38.05
17%
10
- C2 -
4N7R
-
GLUBP_ARATH
C:
[48-299]
--------------------STHKPF
P
A
E
V
S
R
S
I
M
E
L
S
S
V
G
T
L
S
T
L
T
HD
G
W
P
L
G
V
G
----
V
R
F
A
V
D
K
D
G
T
P
V
L
C
L
N
R
S
V
S
P
DK
R
S
A
----
L
H
V
Q
L
-
E
Q
C
G
L
R
T
P
-
Q
C
T
---
I
Q
G
----
S
I
G
R
P
G
D
D
T
V
L
K
R
L
S
A
T
W
R
E
K
F
G
E
E
V
--
K
E
D
S
L
Y
V
----
V
A
V
D
R
V
L
Q
M
E
D
F
--
M
E
D
G
-
I
W
V
A
S
S
D
Y
K
N
----
A
S
P
D
P
L
R
D
I
A
E
D
I
---
V
N
---
Q
I
------
N
A
N
N
M
E
---
D
-
I
--
F
R
F
C
N
V
Y
V
D
L
D
F
V
V
S
E
T
K
M
I
W
M
D
R
L
G
-
F
D
--
L
R
V
W
S
P
R
G
V
Y
D
V
R
I
P
----
F
P
M
E
V
T
--------------
D
E
K
G
A
K
S
S
F
N
G
M
S
Q
------
L
A
W
E
V
E
K
S
Y
C
P
A
D
F
N
K
V
K
L
L
K
Q
V
V
--------------------------------
3
PsiBlast_PDB
37.23
29%
6
- C5 -
3AX6
1
?
A:
[84-137]
------------------------------------------------------------------------------------------------------------------------------
E
G
Y
K
I
H
P
S
P
Y
T
L
E
I
I
Q
D
K
F
V
Q
-
K
E
F
L
K
----
K
N
G
I
P
V
P
E
Y
K
L
V
--
K
D
L
E
-
S
D
V
R
E
F
G
F
P
V
----
V
Q
K
A
R
K
G
G
V
F
I
I
K
---
N
E
---
K
D
------
L
E
N
A
I
K
---
G
-
E
--
T
Y
L
E
E
F
V
E
I
E
K
E
L
A
V
M
V
A
R
N
E
K
-
G
E
I
-
A
C
--
Y
---
P
V
V
E
M
Y
D
T
V
I
A
----
P
A
R
I
E
E
K
Y
S
-
K
I
A
R
E
I
-
A
T
S
V
V
E
A
L
E
G
V
G
I
F
G
I
E
------
M
F
L
T
K
Q
G
E
I
L
V
N
E
I
A
P
R
P
H
N
S
G
H
Y
T
I
E
A
C
V
T
S
Q
-----------------------
7
HHSearch
36.51
14%
-57
- C5 -
1W7W
-
?
A:
[1-54]
-------------------------------------------------------------------------------------------------------
A
-
E
L
E
---
R
T
F
----
I
A
I
K
P
-
D
G
-
V
Q
R
G
------------
L
I
S
E
I
I
S
R
F
E
----
R
K
G
F
K
L
V
G
I
K
V
---
L
I
P
T
-
K
Q
F
A
Q
Q
H
Y
H
D
----
L
K
E
R
P
F
F
N
G
L
C
D
F
---
L
S
---
S
G
------
P
V
I
A
M
V
---
W
-
E
--
G
E
G
V
I
T
Y
G
R
K
L
I
G
A
T
D
P
Q
K
S
A
P
-
G
T
I
-
R
G
--
D
---
L
A
V
V
V
G
R
N
I
I
H
----
G
S
D
G
P
E
T
A
K
-
D
E
I
K
L
W
-
F
K
P
E
E
L
V
S
F
T
S
N
S
E
K
W
I
------
Y
G
------------------------------------------------------
19
Fugue
34.54
15%
40
* C5 *
1FE6
-
?
A:
[1-52]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
-
I
N
E
T
A
D
D
I
V
Y
R
L
T
V
I
I
D
------
D
R
Y
E
S
L
K
N
L
I
T
L
R
A
D
R
L
E
M
I
I
N
D
N
V
S
T
I
L
A
S
G
------------------------
11
HHSearch
34.46
22%
53
- C5 -
2H0A
-
?
A:
[75-101]
-----------------------------------------------------------------------------------------------------------------------------------------
T
E
F
Y
R
R
L
V
E
G
I
E
G
V
L
L
----
E
Q
R
Y
D
L
A
L
F
P
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.02
7%
19
- C5 -
2QUP
1
?
A:
[36-76]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
K
A
Y
E
R
L
Q
A
L
M
S
------
K
I
D
D
Q
-
G
K
L
L
S
E
T
R
T
I
E
E
L
R
K
Y
K
E
L
V
K
E
F
V
G
D
A
-----------------------
12
HHSearch
31.66
15%
-31
- C5 -
3BRQ
1
ASCG_ECOLI
A:
[19-59]
-----------------------------------------------------------------------------------------------------------
T
---
Q
T
L
----
G
L
V
V
T
-
N
T
L
Y
--------
H
--
Y
F
S
E
L
L
F
H
A
A
R
M
A
E
----
E
K
G
R
Q
L
L
L
A
D
G
K
--
H
S
A
E
-
E
E
R
Q
A
I
Q
Y
L
L
----
D
L
R
C
D
A
I
M
I
Y
P
R
F
---
L
S
---
V
D
------
E
I
D
D
I
I
---
D
-
A
--
H
S
Q
P
I
M
V
L
N
R
R
L
R
K
N
S
S
H
S
V
W
C
-
D
H
K
-
Q
T
--
S
---
F
N
A
V
A
E
L
I
N
A
G
----
H
Q
E
I
A
F
L
T
G
-
S
M
D
S
P
T
-
S
I
E
R
L
A
G
Y
K
D
A
L
A
Q
H
G
I
------
A
L
N
E
K
L
I
A
N
G
K
W
T
P
A
S
G
A
E
G
V
E
M
L
L
E
R
K
F
S
A
L
V
-----------------------
2
PsiBlast_PDB
30.95
34%
-39
- C5 -
1J5Y
1
NIAR_THEMA
A:
[82-139]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
S
R
L
V
A
V
--
K
H
A
P
-
E
E
I
K
E
E
L
L
C
V
----
V
R
N
G
G
R
I
V
---
D
V
---
I
V
---
E
H
------
P
V
Y
G
E
I
---
R
G
I
--
I
D
V
S
S
E
E
E
V
L
K
F
V
N
L
M
E
M
A
K
T
E
-
P
L
L
-
T
L
--
S
---
G
G
V
H
L
H
T
I
E
A
P
----
D
E
E
T
M
E
R
I
M
-
R
E
L
K
K
K
-
G
F
L
I
E
E
-------------------------------------------------------------------------
8
HHSearch
28.34
24%
-1
- C5 -
2LCI
-
?
A:
[11-44]
--------------------------------------------------------------------------------------------------------------------------------------------
N
D
E
L
I
K
K
I
K
K
E
V
E
----
N
Q
G
Y
Q
V
R
D
V
N
D
S
--
D
E
L
K
-
K
E
M
K
K
L
A
E
E
K
----
N
F
E
K
I
L
I
I
S
N
D
K
Q
---
L
L
---
K
E
------
M
L
E
L
I
S
---
K
-
L
--
G
Y
K
V
F
L
L
L
Q
D
Q
D
E
N
E
L
E
E
F
K
R
K
-
I
E
S
-
Q
G
--
Y
---
E
V
R
K
V
T
D
D
E
E
A
----
L
K
I
V
R
E
F
M
Q
-
K
A
G
S
L
E
-
H
H
H
H
H
H
-------------------------------------------------------------------------
14
HHSearch
27.67
18%
27
- C5 -
3D8U
-
?
A:
[71-107]
---------------------------------------------------------------------------------------------------------------
Y
S
I
----
A
L
I
I
P
-
S
L
F
----------
E
K
A
C
A
H
F
L
P
S
F
Q
Q
A
L
N
----
K
A
G
Y
Q
L
L
L
G
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
19.53
36%
213
- C4 -
1OT0
1
RL1_HELPY
A:
[1-19]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
K
V
F
K
R
L
E
K
L
F
S
K
I
Q
N
W
K
-----------------------
21
Fugue
19.53
36%
213
* C4 *
1P0J
1
RL1_HELPY
A:
[1-19]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
K
V
F
K
R
L
E
K
L
F
S
K
I
Q
N
W
K
-----------------------